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Common Core Standards for Science and Technical Subjects focus mainly literacy.   Teachers of science are expected to promote skills in students that allow them to read technical nonfiction texts.  Reading standards can be summarized as follows:

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List of cloning lessons

Worksheet: codominance lethal genes multiple alleles polygenic traits

Students can manipulate mutations in bunnies, such as fur color and teeth length. By altering the environmental factors, students can see how the bunny populations change over time. For example, in a warm environment, more bunnies will have brown fur, but in the cold environment, more bunnies will have white fur. The student worksheet includes instructions on how the simulator works. Then students perform a variety of "experiments" to explore mutations in the populations. I include this as part of a unit on evolution, so students are familiar with VIDA charts. Students complete a chart at the end of the activity to summarize how variations in populations lead to adaptation.