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Cancer usually begins with one tumor in a specific area of the body. But if the tumor is not removed, cancer has the ability to spread to nearby organs as well as places far away from the origin, like the brain. How does cancer move to these new areas and why are some organs more likely to get infected than others? Ivan Seah Yu Jun explains the three common routes of metastasis.

Decades ago, few pediatricians had heard of autism. In 1975, 1 in 5,000 kids was estimated to have it. Today, 1 in 68 is on the autism spectrum. What caused this steep rise? Steve Silberman points to "a perfect storm of autism awareness" - a pair of doctors with an accepting view, an unexpected pop culture moment and a new clinical test. But to really understand, we have to go back further to an Austrian doctor by the name of Hans Asperger, who published a pioneering paper in 1944. Because it was buried in time, autism has been shrouded in misunderstanding ever since. (This talk was part of a TED2015 session curated by Pop-Up Magazine: popupmagazine.com or @popupmag on Twitter.)

Your genome, every human's genome, consists of a unique DNA sequence of A's, T's, C's and G's that tell your cells how to operate. Thanks to technological advances, scientists are now able to know the sequence of letters that makes up an individual genome relatively quickly and inexpensively. Mark J. Kiel takes an in-depth look at the science behind the sequence.

For 10,000 years, humanity suffered from the scourge of smallpox. The virus killed almost a third of its victims within two weeks and left survivors horribly scarred. But Simona Zompi commends the brave souls - a Buddhist nun, a boy, a cow, a dairymaid and physician Edward Jenner - who first stopped the spread of this disastrous disease, to make us smallpox-free today.

Diabetes has a history dating back to Ancient Greece. Our treatment of it, however, is more recent and was originally made possible with the help of man's best friend. Due to physiological traits shared with humans, dogs have saved countless lives through the discovery of insulin. Duncan C. Ferguson shares the story of the canine's great contribution to man -- and how we can all reap the medical benefits.

Within every cell in our body, two copies of a tumor suppressor gene called BRCA1 are tasked with regulating the speed at which cells divide. Michael Windelspecht explains how these genes can sometimes mutate, making those cells less specialized and more likely to develop into cancer.

Cells are everywhere. Even though most can't be seen with the naked eye, they make up every living thing. Your body alone contains trillions of cells. Students will be able to explain why cells are small and calculate a cell's surface area to volume ratio.

Published on Feb 19, 2015 View full lesson: http://ed.ted.com/lessons/what-does-t... Beneath your ribs, you'll find, among other things, the pancreas -- an organ that works a lot like a personal health coach. Emma Bryce explains how this organ controls your sugar levels and produces a special juice that releases the nutrients from your food to help keep you in the best possible shape. Lesson by Emma Bryce, animation by Tremendousness.

Today, about one-tenth of the world's population are southpaws. Why are such a small proportion of people left-handed -- and why does the trait exist in the first place? Daniel M. Abrams investigates how the uneven ratio of lefties and righties gives insight into a balance between competitive and cooperative pressures on human evolution. Lesson by Daniel M. Abrams, animation by TED-Ed.

6:12 video, short quiz, open response

4:30 video View full lesson: http://ed.ted.com/lessons/why-it-s-so...↵↵In 2008, something incredible happened: a man was cured of HIV. In over 70 million HIV cases, this was a first, and, so far, a last, and we don't yet understand exactly how he was cured. But if we can cure people of various diseases, like malaria and hepatitis C, why can't we cure HIV? Janet Iwasa examines the specific traits of the HIV virus that make it so difficult to cure.↵↵Lesson by Janet Iwasa, animation by Javier Saldeña.

The DNA in just one of your cells gets damaged tens of thousands of times per day. Because DNA provides the blueprint for the proteins your cells need to function, this damage can cause serious issues-including cancer. Fortunately, your cells have ways of fixing most of these problems, most of the time. Monica Menesini details the processes of DNA damage and repair.

5:11 video Chat with a friend about an established scientific theory, and she might reply, "Well, that's just a theory." But a conversation about an established scientific law rarely ends with "Well, that's just a law." Why is that? What is the difference between a theory and a law... and is one "better"? Matt Anticole shows why science needs both laws and theories to understand the whole picture.

This case study is designed to teach basic concepts of genetics by focusing on a rare disease, pseudoxanthoma elasticum (PXE).  Chromosome 16 is the narrator at the beginning of the case and introduces students to genes, chromosomes and mutations. The focus then shifts to the patient and his mother as she finds out about her son's disease and her subsequent efforts to connect with patient advocacy groups for support. The case concludes with students watching a TED talk given by Sharon Terry, the real-life mother on whom this story is loosely based, so that students can connect on an emotional and human level with someone who has intimate experience as a parent of children with a rare genetic disease. The case is suitable for high school general biology classes, but it can also be used by biology major or non-major undergraduates in a lower-division biology class, or in any lower-division non-major class focused on human disease.

More than 40 million people worldwide suffer from Alzheimer's disease, and that number is expected to increase drastically in the coming years. But no real progress has been made in the fight against the disease since its classification more than 100 years ago. Scientist Samuel Cohen shares a new breakthrough in Alzheimer's research from his lab as well as a message of hope. "Alzheimer's is a disease," Cohen says, "and we can cure it."

The highly virulent Ebola virus has seen a few major outbreaks since it first appeared in 1976 -- with the worst epidemic occurring in 2014. How does the virus spread, and what exactly does it do to the body? Alex Gendler details what Ebola is and why it's so hard to study.

15min How do vaccines prevent disease - even among people too young to get vaccinated? It's a concept called "herd immunity," and it relies on a critical mass of people getting their shots to break the chain of infection. Health researcher Romina Libster shows how herd immunity contained a deadly outbreak of H1N1 in her hometown. (In Spanish with subtitles.)

You may remember neuroscientist Miguel Nicolelis - he built the brain-controlled exoskeleton that allowed a paralyzed man to kick the first ball of the 2014 World Cup. What's he working on now? Building ways for two minds (rats and monkeys, for now) to send messages brain to brain. Watch to the end for an experiment that, as he says, will go to "the limit of your imagination."