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Sure, we know insufficient serotonin levels get a bad rap when it comes to depression, but that's like blaming one person in a full-scale riot. Depression isn't caused by only one factor. In fact, study co-author Elyse Aurbach says we're probably not getting to the core of why people are depressed because "the brain is immensely complex." In this study, the research team conducted eight experiments (four on animal brains, four on brains of the deceased human kind) of varying sample sizes - from 20 to 90 brains in each - and found that the brains of deceased humans who'd been depressed had increased levels of hippocampal FGF9 and that live animals with increased FGF9 levels demonstrated depressive, anxious behavior. "This is not just a correlation," study leader Huda Akil of the University of Michigan says. Less really may be more, at least when it comes to FGF9.

Plant species belonging to divergent branches of the evolutionary tree are known to have independently evolved caffeine production. According to scientists at Western Michigan University, caffeine-producing plants have taken a number of different biochemical routes to synthesize the stimulant. Coffee, tea, cocoa, orange, and guaraná plants make caffeine using an array of enzymes and substrates, the researchers reported in PNAS this week (September 20).

However, new research led by Michigan State University psychology professor David Z. Hambrick suggests that, unfortunately for many of us, success isn't exclusively a product of determination - that despite even the most hermitic practice routine, our genes might still leave greatness out of reach.

A new study shows that gene editing using CRISPR/Cas9 technology can work in rhesus monkey embryos. The results, published in the current issue of Human Molecular Genetics, open the door for pursuing gene editing in nonhuman primates as models for new therapies, including pharmacological, gene-, and stem cell-based therapies, says Keith Latham, animal science professor at Michigan State University and lead author of the study.

imaging of embyro collection