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This flipped clicker case study explores the fascinating relationship between the Arizona Bark Scorpion (the most venomous scorpion in North America) and the Southern Grasshopper Mouse. Initially it would seem that the grasshopper mouse is no match for the scorpion's venom; however, the grasshopper mouse is easily able to eat the scorpion and is largely immune to the scorpion's sting. By working through this case study, students learn about neuron anatomy and physiology as they explore how the grasshopper mouse is able to survive the scorpion's venom. This case study was developed for an introductory biology course for majors, but it could also be used in an introductory biology course for non-majors or in an anatomy and physiology course. The case requires that students learn basic neuron anatomy and action potential physiology prior to class by reading their textbook or by watching videos on the subjects. An optional set of guided questions tailored to Campbell Biology (10th ed.) is included in the teaching notes.

The most venomous animal on the planet isn't a snake, a spider, or a scorpion; it's a snail-a cone snail, to be precise. The Conus genus boasts a large variety of marine snails that have adopted an equally diverse assortment of venoms. Online today in the Proceedings of the National Academy of Sciences, researchers report an especially interesting addition to the animals' arsenal: insulin. According to the paper, this marks the first time insulin has been discovered as a component of venom.

So how do animals play a role in this research? Well, in a couple of ways. First, the chlorotoxin in Tumor Paint was derived from scorpion venom. Second, researchers worked with dogs before moving into human trials to determine the likelihood of success. After promising results in canines, human trials are now underway at Cedars Sinai Medical Center! Right now, the study is aimed at proving that Tumor Paint is able to reach the brain tumor successfully. If all goes well, it's possible that this could lead to more successful surgical outcomes.

Venom - information on protein structure and function, following scenario of a scorpion bite.  Interactive game and activities included on site.