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MOD invites all qualified scientists with faculty appointments or the equivalent, at universities, hospitals and research institutions (not for profit or profit), to submit applications for research grants relevant to our mission. This encompasses basic biological processes governing differentiation and development, genetics and genomics of these processes, clinical studies, reproductive health and environmental toxicology, and social and behavioral studies concerning cognitive and behavioral risks that affect outcomes of pregnancy, the perinatal period, and subsequent child development. Applications will be directed to one of three committees whose respective foci are:    * Cell Lineage and Differentiation  * Gene Discovery and Translational Medicine  * Social and Behavioral Sciences. This involves family units and includes genes, toxicants, social  determinants that adversely affect language or behavior, especially if involving premature  infants or children with birth defects.

This award is designed to support young scientists just embarking on their independent research careers.  The applicants' research interests should be consonant with those of the March of Dimes' mission: The  Mission of the March of Dimes is to improve the health of babies by preventing birth defects, premature birth and infant mortality. The March of Dimes defines a birth defect as any abnormality of structure or function, whether inherited, or acquired in utero and presenting in infancy or early childhood. Deviations from reproductive health of women and men as an underlying basis of birth defects, i.e. preconceptional events, perinatal course, and premature births, are appropriate subjects for research support. Relevance is interpreted broadly to include fundamental cell biology (embryogenesis, cell lineage, differentiation), genetics and genomics, fundamental cellular and clinical pathogenesis of disorders of importance to mothers and infants, biomedical engineering and imaging, and social and behavioral aspects. Each application should be accompanied by a Letter of Support from a Nominator (see below). The award is $150,000 for two years, including 10 percent indirect costs to sponsoring institutions.

The Foundation accepts applications for grants to conduct research on the effects of alcohol consumption on health and behavior. The following areas are of greater interest: Studies on how particular patterns of consumption (quantity of alcohol consumed, types of alcoholic beverages consumed, frequency of consumption and context) are related to health and behavioral outcomes. Interdisciplinary, bio-informatics, and other approaches to elucidate genetic and environmental factors that influence the patterns of consumption of alcoholic beverages and related consequences. The Foundation encourages basic and clinical research, including epidemiology. Examples of research topics include factors influencing underage drinking, mechanisms of alcohol-related organ injury, fetal alcohol spectrum disorders, and effects of alcohol on general health.   The Foundation gives preference to young investigators, but does not support students or trainees in pre- or post-doctoral programs. It does not fund thesis or dissertation research. Grants are made to academic and research institutions in the United States, Canada and South Africa, not to individuals. Evidence of support for the investigator from the institution is desirable. 

The ADAA Career Development Travel Awards are given to help early career professionals who have a research interest in anxiety disorders and depression, such as basic and clinical neurobiology, psychopharmacology, anxiety comorbidities, clinical psychology, genetics, neuroimaging, epidemiology, comparative effectiveness, multicultural issues, public health, as well as other areas. The awards also familiarize and engage aspiring professionals with the membership and work of the association.

This FOA encourages R01 applications from institutions/organizations that propose to study the neurobiological and behavioral mechanisms that might explain how alcohol and stimulants interact at genetic, epigenetic, cellular, neurocircuitry and behavioral levels to promote co-addiction.

This FOA encourages R01 applications from institutions/organizations that propose to study the neurobiological and behavioral mechanisms that might explain how alcohol and stimulants interact at genetic, epigenetic, cellular, neurocircuitry and behavioral levels to promote co-addiction.

This Funding Opportunity Announcement (FOA) aims to stimulate the broader research community to utilize a resource funded through the American Recovery and Reinvestment Act of 2009 (Recovery Act) to generate and evaluate hypotheses about the complex interrelationships and multi-directional influences among genetics, brain maturation, neurocognitive function, and psychiatric symptoms during development. This FOA is a strategic effort to disseminate this data resource, stimulate the broader research community to use the resource, and accelerate research on neurodevelopment and trajectories of risk for mental illness. Secondary goals of this initiative are to foster collaborations among researchers from diverse fields of expertise, enhance diversity of research questions and analytic approaches, advance methods for integration across data modalities and levels of analyses (i.e., imaging, genomics, behavior), and encourage inclusion of early stage investigators among these collaborations.

CHADD is now accepting applications for the 2014 Young Scientist Research Fund Awards.  The program recognizes researchers new to the ADHD field who are making contributions to the understanding of ADHD.  Through the Fund, CHADD supports researchers with: an unrestricted cash award of $5,000 each recognition at CHADD's Annual International Conference an allowance to cover most conference related expenses (travel, hotel, registration)  a one-year CHADD professional membership. Applicants must be in the process of completing a doctoral degree or must have completed such a degree within the last three years with the doctoral degree awarded no earlier than January 2011.  They must be involved in conducting research addressing an area of ADHD that will further understanding of the disorder.  Research may address any area relevant to ADHD, including, but not limited to: biological/genetic underpinnings of the disorder; treatment efficacy; impact on the individual or family; school or workplace accommodations; social stigma and discrimination; public health; and epidemiology.

The purpose of this Funding Opportunity Announcement (FOA) and the companion FOA is to solicit applications for computational and functional analysis of gene networks and complex pathways that confer susceptibility to severe mental illnesses. These studies should leverage existing diverse multi-scale datasets and apply a combination of cutting-edge bioinformatics, computational predictive modeling, and systems biology approaches to identify and begin to evaluate novel genetic factors and molecular networks underlying functional pathways relevant to psychiatric disorders to verify their relationship or causality with disease/disease risk.  The computational model predictions should be further replicated through independent datasets and confirmed using biological measures from existing and/or new experimental data.

The purpose of this Funding Opportunity Announcement (FOA) and the companion FOA is to solicit applications for computational and functional analysis of gene networks and complex pathways that confer susceptibility to severe mental illnesses. These studies should leverage existing diverse multi-scale datasets and apply a combination of cutting-edge bioinformatics, computational predictive modeling, and systems biology approaches to identify and begin to evaluate novel genetic factors and molecular networks underlying functional pathways relevant to psychiatric disorders to verify their relationship or causality with disease/disease risk.  The computational model predictions should be further replicated through independent datasets and confirmed using biological measures from existing and/or new experimental data.

The annual program is designed to support research on suicide from a variety of disciplines, including psychiatry, medicine, psychology, genetics, epidemiology, neurobiology, sociology, nursing, health services administration, social work, and many others. Grants of up to $300,000 over two years will be awarded to investigators at any level performing research involving two or more unique sites, with each site contributing unique expertise as well as data collection.

This FOA invites applications that propose the comprehensive functional validation of newly identified therapeutic target candidates for Alzheimer's Disease-Related Dementias (ADRDs). This FOA seeks to promote critical target validation approaches to help de-risk subsequent translational research and accelerate the advancement of novel therapies for ADRD. Target(s) or molecular pathway(s) to be considered for validation must have been already identified using tissue expression or genetic data generated in human samples. In its initial phase, this FOA provided support for up to two years (UG3 stage) for the development of customized technologies, models, and protocols to modulate the expression or activity of target candidate(s) in cells or tissues and monitor their functional biological consequences in in vitro or in vivo disease models. Upon demonstration of technical feasibilities, a second phase (UH3 stage) will carefully and reproducibly measure and cross-validate the impact of the target modulation in different modalities across collaborating laboratories using the NIH rigor and reproducibility guidelines. Applicants responding to this FOA must address objectives for both the UG3 and UH3 phases and are expected to have a substantial collaborative effort between independents laboratories. This FOA is not specific for any one or group within the ADRD spectrum of disorders. Disorders covered in these applications are frontotemporal degeneration (FTD), Lewy body dementias (LBD) (including dementia with Lewy bodies (DLB)), Parkinson disease dementia (PDD), vascular contributions to cognitive impairment and dementia (VCID), mixed dementias including the associated diagnostic challenges of multiples etiology dementias (MED).

Tþffþffhis FOA invites applications that propose the comprehensive functional validation of newly identified therapeutic target candidates for Alzheimer's Disease-Related Dementias (ADRD).  This FOA seeks to promote critical target validation approaches to help de-risk subsequent translational research and accelerate the advancement of novel therapies for ADRD. Target(s) or molecular pathway(s) to be considered for validation must have been already identified using tissue expression or genetic data generated in human samples. In its initial phase, this FOA provides support for up to two years (UG3 stage) for the development of customized technologies, models, and protocols to modulate the expression or activity of target candidate(s) in cells and/or tissues and monitor their functional biological consequences in in vitro or in vivo disease models.  Upon demonstration of technical feasibilities, a second phase (UH3 stage) will carefully and reproducibly measure and cross-validate the impact of the target modulation in different modalities across collaborating laboratories using the NIH rigor and reproducibility guidelines. Applicants responding to this FOA must address objectives for both the UG3 and UH3 phases and are expected to have a substantial collaborative effort between independent laboratories.

The purpose of this Funding Opportunity Announcement (FOA) is to encourage institutions to propose creative and innovative institutional research career development programs which prepare clinically-trained vision scientists for independent research careers. This initiative is intended to expand and strengthen the community of investigators engaged in clinical research. Such an increase in the number of well-trained clinical researchers is necessary to achieve a pool of scientists with contemporary, multidisciplinary expertise able to leverage recent advances in ocular genetics, therapeutics, bioengineering, and bio-behavioral research in order to enhance patient treatment and to increase scientific momentum in these fields. This Funding Opportunity Announcement (FOA) allows appointment of Scholars (K12) proposing a separate ancillary study to an existing trial or proposing to gain research experience in a clinical trial led by another investigator, as part of their research and career development. Applications supported by this FOA that meet the NIH definition of a clinical trial (see NOT-OD-15-015) must also fulfill the NIH requirements for either a mechanistic or minimal risk trial. A mechanistic trial is designed to understand a biological or behavioral process, the pathophysiology of a disease, or the mechanism of action of an intervention. A minimal risk trial is one in which the probability and magnitude of harm or discomfort anticipated in the research are not greater in and of themselves than those ordinarily encountered in daily life or during the performance of routine physical or psychological examinations or tests. A proposed research career development program that includes a clinical trial that is not a mechanistic trial and/or involves a level of risk beyond that defined as minimal, will not be supported.

The annual program is designed to support research on suicide from a variety of disciplines, including psychiatry, medicine, psychology, genetics, epidemiology, neurobiology, sociology, nursing, health services administration, and social work. Grants of up to $300,000 over two years will be awarded to investigators at any level performing research involving two or more unique sites, with each site contributing unique expertise as well as data collection.

Each ACT Fellowship will provide up to $220,000 for up to thirty-three months in support of a systematic and sustained course of study in an empirical science such as physics, psychology, biology, genetics, cognitive science, neuroscience, or sociology. Acceptable courses of study might include a plan to audit undergraduate and graduate-level courses, a plan to spend time in residence at a research lab, or a plan to earn a degree in an empirical science. This iteration of the program also will permit applicants to request that up to one year of the ACT Fellowship be used to support a small-scale pilot scientific research project that improves or enhances the capacity, skill, and talent of the fellow to investigate the above-described Big Questions. Fellows may undertake their study at their home institution or another institution. All fellows must have a faculty mentor in their cross-training discipline.

his Funding Opportunity Announcement (FOA) invites applications for specialized Alcohol Research Centers using the P50 mechanism. The overall purpose of the NIAAA Alcohol Research Center program is to provide leadership in conducting and fostering interdisciplinary, collaborative research on a wide variety of topics relevant to the Institutes mission. These topics include, but are not limited to: the nature, etiology, genetics, diagnosis, treatment, and prevention of alcohol use disorders and their biomedical, psychosocial, and economic consequences across the lifespan. Centers also are regional or national resources that contribute to the development of new research methods, technologies and approaches that sustain innovative goal-directed research.

 This Funding Opportunity Announcement (FOA) invites applications for specialized Alcohol Research Centers using the P50 mechanism.  The overall purpose of the NIAAA Alcohol Research Center program is to provide leadership in conducting and fostering interdisciplinary, collaborative research on a wide variety of topics relevant to the Institute's mission.  These topics include, but are not limited to: the nature, etiology, genetics, diagnosis, treatment, and prevention of alcohol use disorders and their biomedical, psychosocial, and economic consequences across the lifespan.  Centers also are regional or national resources that contribute to the development of new research methods, technologies and approaches that sustain innovative goal-directed research

The foundation encourages basic and clinical research, including epidemiology. Examples of research topics include factors influencing underage drinking, mechanisms of alcohol-related organ injury, fetal alcohol spectrum disorders, and the effects of alcohol on general health. Areas of particular interest include studies on how particular patterns of consumption (quantity of alcohol consumed, types of alcoholic beverages consumed, frequency of consumption, and context) are related to health and behavioral outcomes; and interdisciplinary, bioinformatics and other approaches to genetic and environmental factors that influence the patterns of consumption of alcoholic beverages and related consequences.

The Autism Science Foundation is inviting applications for its Pre- and Postdoctoral Training Awards from graduate students, medical students, and postdoctoral fellows interested in pursuing careers in basic and clinical research relevant to autism spectrum disorders. The proposed training must be scientifically linked to autism and may be broadened to include training in a closely related area of scientific research, including but not limited to human behavior across the lifespan (language, learning, behavior, communication, social function, motor skills & planning, epilepsy, sleep, repetitive disorders), neurobiology (anatomy, development, neuroimaging), pharmacology, neuropathology, genetics, epigenetics, genomics, epigenomics, immunology, molecular and cellular mechanisms, studies employing model organisms and systems, and studies of treatment and service delivery. Special consideration will be given to projects focused on gender issues in autism. This includes studies examining the female protective effect, neurobiological and neuroanatomical examination of the female autism brain, diagnostic differences and challenges in females, the female phenotype, and health and lifespan issues, including vocational services and employment. ASF also invites studies focused on unaffected siblings and recurrence risk in the offspring of unaffected siblings. ASF is also interested in supporting research on the neurobiology and molecular biology of autism using post-mortem brain tissue. The one-year awards include $25,000 for predoctoral and medical students and $35,000 for postdoctoral students.