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MiamiOH OARS on 17 Dec 12The National Heart, Lung, and Blood Institute invites cooperative agreement (U01) applications to investigate and define cellular and molecular events, including host genetic factors, underlying the pathogenesis of HIV-associated lung diseases (e.g., COPD and pulmonary hypertension). Biospecimens and clinical data from HIV-infected patients and controls should be utilized. Clinical translation is encouraged to the extent that it is possible. Both independent (site-specific) and collaborative research with other groups funded by this FOA will be conducted under this program. The goals are to identify disease sub-phenotypes, potential biomarkers to predict risk, progression, and outcome, and molecular targets to help design therapeutic interventions.