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This Funding Opportunity Announcement (FOA) seeks to stimulate research on mid-life adults (those 50 to 64 years of age) that can inform efforts to optimize health and wellness as individuals age, and prevent illness and disability in later years.

The goal of this FOA is to support basic and clinical research on the influence of alcohol on susceptibility and progression of Alzheimer's disease and its related dementias. Recent longitudinal studies have provided strong evidence that alcohol use disorder is associated with the high risk of all types of dementias, and frequent heavy drinking increases risk of both Alzheimer's disease and vascular dementia. Even moderate alcohol consumption may be a risk factor for adverse brain outcomes and cognitive decline. Although these studies link heavy and frequent alcohol drinking to dementias in aging populations, mechanisms contributing to this relationship are not well understood. With this FOA, we solicit research projects that combine diverse expertise and use innovative approaches to investigate mechanisms by which alcohol affects brain aging processes to produce dementias and influences development of Alzheimer's disease. This FOA strongly encourages collaborations between alcohol researchers and experts in Alzheimer's disease and its related dementia research

The Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Substance Abuse Prevention (CSAP), is accepting applications for fiscal year (FY) 2013 Strategic Prevention Framework Partnerships for Success cooperative agreements (SPF-PFS). The SPF-PFS is designed to address two of the nation's top substance abuse prevention priorities: 1) underage drinking among persons aged 12 to 20; and 2) prescription drug misuse and abuse among persons aged 12 to 25.

The goal of this FOA is to support research that will lead to a greater understanding of complex mechanisms by which the brain glymphatic system and meningeal and peripheral lymphatic systems change in normal and pathological brains. This knowledge is critical to determine whether a functional impairment or disruption of these systems may be involved in neurological disorders that are associated with immune system dysfunction, such as Alzheimer's disease.

The purpose of this FOA is to support an initial series of activities over a 3-year period to build the foundation for enhanced collaborations across NIA's 6 centers programs. These collaborations are intended to leverage NIA's substantial investments by fostering the development of novel interdisciplinary efforts in aging research. This opportunity will provide resources to build additional infrastructure and establish specific collaborative activities that could include, but are not limited to, information and data exchange, meetings and conferences, pilot studies, research opportunities for beginning investigators, visiting scholar programs, dissemination, and other collaborative efforts. The successful awardee will involve all 6 centers programs.

AFAR provides up to $100,000 for a one- to two-year award to junior faculty (M.D.s and Ph.D.s) to conduct research that will serve as the basis for longer term research efforts. AFAR-supported investigators study a broad range of biomedical and clinical topics including the causes of cellular senescence, the role of estrogen in the development of osteoporosis, the genetic factors associated with Alzheimer's disease, the effects of nutrition and exercise on the aging process, and much more. Since 1981, over 680 AFAR Research Grants have been awarded.

This Funding Opportunity Announcement (FOA) encourages innovative, hypothesis-driven R01 research grant applications that can expand understanding of the role and impact of families and interpersonal relationships on health and well-being in midlife and older age.

The purpose of the National Chronic Disease Self-Management Education (CDSME) Resource Center will be to provide leadership, expert guidance, and resources to promote the value of and increase access to evidence-based self-management programs; and to serve as a national clearinghouse and disseminate resources and best practices to increase the capacity of states, aging, disability and public health networks and their partners to implement and sustain CDSME programs.

The purpose of the National Chronic Disease Self-Management Education (CDSME) Resource Center will be to provide leadership, expert guidance, and resources to promote the value of and increase access to evidence-based self-management programs; and to serve as a national clearinghouse and disseminate resources and best practices to increase the capacity of states, aging, disability and public health networks and their partners to implement and sustain CDSME programs.

The purpose of the National Chronic Disease Self-Management Education (CDSME) Resource Center will be to provide leadership, expert guidance, and resources to promote the value of and increase access to evidence-based self-management programs; and to serve as a national clearinghouse and disseminate resources and best practices to increase the capacity of states, aging, disability and public health networks and their partners to implement and sustain CDSME programs.

The purpose of the National Chronic Disease Self-Management Education (CDSME) Resource Center will be to provide leadership, expert guidance, and resources to promote the value of and increase access to evidence-based self-management programs; and to serve as a national clearinghouse and disseminate resources and best practices to increase the capacity of states, aging, disability and public health networks and their partners to implement and sustain CDSME programs.

The goal of this FOA is to test whether or not the ages of laboratory animals is an important consideration in experimental outcomes in the study of disease pathology, degenerative condition, response to therapy, intervention or environmental exposure. The majority of studies of human conditions and diseases in laboratory animals are done using young animals. 

The National Institute for Occupational Safety and Health (NIOSH)/Centers for Disease Control and Prevention (CDC) invites applications for Centers for Agricultural Safety and Health (Ag Centers). Ag Centers are expected to conduct high quality research and help translate scientific discoveries into practical applications to improve worker safety and health in the areas of agriculture, forestry, and fishing. 

The purpose of this NOFO is to enhance the capacity of surveillance programs to implement a population-based, multiple source surveillance program for autism spectrum disorder (ASD). The project will fund sites to participate in the Autism and Developmental Disabilities Monitoring (ADDM) Network and will enhance surveillance activities at both prior and newly participating sites through two funding components. Component A is required for all applicants, while applying for Component B funding is optional. Component A funds surveillance of autism spectrum disorder (ASD) among 4-year-old and 8-year-old children. Component A activities include: adhere to standardized ADDM Network methodology; renew or establish agreements for access to BOTH health and education data sources (electronic and paper records); staff training and continued education; report clean, de-identified data with vital records/census linkages to CDC; submit at least two manuscripts; engage partners and stakeholders in activities aimed at increasing use of ADDM data; and create and implement a strategic plan for performance monitoring and evaluation. Component B funds conducting follow-up at age 16 years of children abstracted for ASD at age 8 years in 2010 and 2012, including collecting data on characteristics, functioning, and educational service delivery (including transition planning). These data will inform public health strategies to improve identification and services for children with ASD.

The purpose of this Funding Opportunity Announcement (FOA) is to stimulate exploratory or developmental research that can help to inform future, targeted interventions to address risk factors, access barriers, oral health promotion and disease prevention strategies, and clinical management of dental, oral, and craniofacial (DOC) diseases associated with aging. Collaborations between researchers focused on aging and researchers focused on DOC health will be strongly encouraged.

THE ADMINISTRATION for Children and Families, Administration on Children, Youth and Families' Family and Youth Services Bureau (FYSB) announces the availability of funds under the Basic Center Program (BCP). THE BCP works to establish or strengthen community-based programs that meet the immediate needs of runaway and homeless youth up to age 18 years of age and their families. BCPs provide youth with emergency shelter, food, clothing, counseling and referrals for health care. Basic centers can provide temporary shelter for up to 21 days for youth and seeks to reunite young people with their families, whenever possible, or to locate appropriate alternative placements. Additional services may include: street-based services; home-based services for families with youth at risk of separation from the family; drug abuse education and prevention services. THE PRIMARY purpose of the BCP is to provide counseling services to youth who have left home without permission of their parents or guardians have been forced to leave home, or other homeless youth who might end up in contact with law enforcement or in the child welfare, mental health, or juvenile justice systems. THE AWARD process for FY2018 BCP allows for annual awards over a three-year project period as funds are available.

The purpose of this Funding Opportunity Announcement (FOA) is to support new and innovative epidemiology research in reproductive age women living with HIV. NICHD plans to establish new epidemiology cohorts of least 2000 participants to stimulate research on a wide range of HIV research hypotheses pertinent to reproductive age women. This new research will help to define and understand clinical outcomes over the course of young women's reproductive lives, including on the effects of HIV and antiretroviral treatment during pregnancies and post-partum and lactation periods, including but not limited to contraception, drug-drug interaction, and pregnancy outcomes.

This RFA invites applications for planning awards to develop and finalize protocols for well-powered cognitive training intervention trials to remediate or prevent age-related cognitive decline as well as possibly prevent or delay the onset of mild cognitive impairment and dementia. Planning activities may include the collection of pilot data and the refinement of cognitive training protocols consistent with Stage I of the NIH Stage Model. Trial designs must justify the means used to assess cognition and to explore the underlying mechanisms of change. Such methods as structural and functional neuroimaging with biomarkers justified by an underlying model of change, CSF fluids, and blood biomarkers are appropriate candidate tools.

: The purpose of this program is to improve access to treatment and support services for youth and young adults, ages 16-25, who have a serious emotional disturbance (SED) or a serious mental illness (SMI), hereafter referred to as serious mental disorders. It is expected that this program will improve emotional and behavioral health functioning so that this population of youth and young adults can maximize their potential to assume adult roles and responsibilities and lead full and productive lives.Youth and young adults with SMI or SED between the ages of 16-25, including those with intellectual developmental disabilities, may not be working, in school, or in vocational and higher education programs. Some face the additional challenge of experiencing homelessness, or being in contact with the juvenile or criminal justice system, thereby increasing the likelihood of admissions to hospitals, mental health, and/or correctional facilities.

NICHD plans to establish new epidemiology cohort(s) of least 2000 participants to stimulate research on a wide range of HIV research hypotheses pertinent to reproductive age women. The purpose of this Funding Opportunity Announcement (FOA) is to support new and innovative epidemiology research in reproductive age women living with HIV.

Today, more than six million children around the world die needlessly before reaching the age of five. Some of the leading causes of child death include preterm birth complications, pneumonia, intrapartum-related complications, diarrhea, and sepsis/ meningitis. Applicants from all walks of life, and from all over the world, are invited to submit a proposal outlining how they plan to save the lives of children under the age of five who would otherwise die from a treatable and preventable cause. All proposals must include a science-based approach to measuring and evaluating the impact of the lives saved. One winner will be awarded $250,000 to directly execute the proposed project.

The Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Substance Abuse Prevention (CSAP) is accepting applications for fiscal year (FY) 2018 Strategic Prevention Framework - Partnerships for Success grants. The purpose of this grant program is to address one of the nation's top substance abuse prevention priorities; underage drinking among persons aged 9 to 20. At their discretion, states/tribes may also use grant funds to target up to two additional, data-driven substance abuse prevention priorities, such as the use of marijuana, cocaine, or methamphetamine, etc. by individuals ages 9 and above. SPF-PFS is designed to ensure that prevention strategies and messages reach the populations most impacted by substance abuse. The program extends current established cross-agency and community-level partnerships by connecting substance abuse prevention programming to departments of social services and their community service providers. This includes working with populations disproportionately impacted by the consequences of substance use; i.e., children entering the foster care system, transitional youth, and individuals that support persons with substance abuse issues (women, families, parents, caregivers, and young adults).