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The Understanding the Rules of Life: Microbiome Theory and Mechanisms (URoL:MTM) program is an integrative collaborationacross Directorates and Offices within the National Science Foundation. The objective of URoL:MTM is to understand and establish the theory and mechanisms that govern the structure and function of microbiomes, a collection of microbes in a specific habitat/environment. This may include but is not limited to host-associated microbiomes, such as those with humans and other organisms, where i) the microbiome impacts host physiology, behavior, development, and fitness; ii) the host influences the metabolic activity, dynamics and evolution of the microbiome, and iii) the environment (biological, chemical, physical, and social) influences and is influenced by both the host and the microbiome. Recent progress has transformed our ability to identify and catalogue the microbes present in a given environment and measure multiple aspects ofbiological, chemical, physical, and social environments that affect the interactions among the members of the microbiome, the host, and/or habitat. Much descriptive and correlative work has been performed on many microbiome systems, particularly those in the human, soil, aquatic, and built environments. This research has resulted in new hypotheses about the microbiome's contributions to potential system function or dysfunction. The current challenge is to integrate the wide range of accumulated data and information and build on them to develop new causal/mechanistic models or theories of interactions and interdependencies across scales and systems.

The EBRC (Energetics Basic Research Center) is a basic research program initiated by the Combat Capabilities Development Command/Army Research Laboratory/ARO. It focuses on areas of strategic importance to U.S. national security. It seeks to increase the Army's intellectual capital in energetic materials (EM) and improve its ability to address future challenges. EBRC brings together universities, research institutions, companies, and individual scholars and supports multidisciplinary and cross-institutional projects addressing specific topic areas determined by the Department of the Army (DA). The EBRC aims to promote research in specific areas of EMs and to promote a candid and constructive relationship between DA and the energetics research community. The future Army is projected to be unable to achieve dominance in range and lethality due to inadequate energetic formulations and form factor limitations associated with current weapon systems. Basic research generates new knowledge that may be exploited to develop and deliver new materials and technologies that contribute to enhanced lethal effects at the system level as well as increased range and a smaller payload. These, in turn, enable space for larger, mission-critical systems, and shorter time-to-target ensuring Army battlefield dominance in Multi-Domain Operations. Army research must encompass new ways to expedite the discovery, design, and scale-up of new materials and concepts which when integrated into newly designed weapons components (e.g. additively manufactured high strength steels with pre-formed fragmentation patterns, and structural reactive materials) developed at ARL and across the Army and DoD communities, will deliver decisive weapons overmatch.

The focus of this BAA is primarily on projects that continue to advance the systems engineering approach needed for the design, fabrication, and manufacture of structural components to address challenges in system weight, performance, affordability, and/or survivability. The foundation of this approach should include the integration of materials information, captured in computational tools, with engineering product performance analysis and manufacturing-process simulation termed commonly as Integrated Computational Materials Engineering (ICME). From this foundation it is expected the integration of manufacturing process information and product performance information utilizing the full range of engineering and analytical tools, processes, and principles to improve efficiency and effectiveness of their integrated approach. The intent is to bring together materials designers, materials suppliers, product designers, and manufacturers to collaborate on the design, production, and commercialization of novel affordable, manufacturable systems. Projects may include basic and applied research, technology and component development, and prototyping; but may also focus on manufacturing supply-chain technical support and integration, workforce development, and manufacturing education.

This is one of two virtual OFRN Round 5 funding information sessions before the formal release of the OFRN SOARING Round 5 RFP. Each session will have the same structure. During the session, OFRN will give a brief overview of the pre-release document, and then OFRN federal partner participants will be available to address specific questions relating to the Areas of Interest.