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Program supports two main types of research: (i) innovations in general-purpose methodology related to optimization, stochastic modeling, and decision and game theory; and (ii) research grounded in relevant applications that require the development of novel and customized analytical and computational methodologies. Both types of proposals must be motivated by an application area of interest to the program. Application areas of interest include supply chains and logistics; risk management; healthcare; environment; energy production and distribution; mechanism design and incentives; production planning, maintenance, and quality control; and national security

The Office ofAdvanced Cyberinfrastructure (OAC) supports translational research and education activities in all aspects of advanced cyberinfrastructure (CI) that lead to deployable, scalable, and sustainable systems capable of transforming science and engineering research. Advanced CI includes the spectrum of computational, data, software, networking, and security resources, tools, and services, along with the computational and data skills and expertise, that individually and collectively can transform science and engineering. OAC supports advanced CI research to address new CI frontiers for discovery leading to major innovations, and supports the development and deployment processes, as well as expert services, necessary for realizing the research CI that is critical to the advancement of all areas of science and engineering research and education. OAC research investments are characterized by their translational nature, i.e., building on basic research results and spanning the design to practice stages. They are further characterized by one or more of the following key attributes: multi-disciplinary, extreme-scale, driven by science and engineering research, end-to-end, and deployable as robust research CI. Areas of translational research supported by OAC include systems architecture and middleware for extreme-scale systems, scalable algorithms and applications, and the advanced CI ecosystem. Principal investigators (PIs) are strongly encouraged to contact an OAC cognizant program director listed in this solicitation with a 1-page project summary for further guidance. For foundational computer and information science and engineering research, PIs are referred to the core research programs of the Computer and Communication Foundations (CCF), Computer and Network Systems (CNS), and Information and Intelligent Systems (IIS) divisions of CISE. Proposers are invited to submit proposals in one project class, which is defined as follows:

The Advanced Manufacturing (AM) program supports the fundamental research needed to revitalize American manufacturing to grow the national prosperity and workforce, and to reshape our strategic industries. The AM program accelerates advances in manufacturing technologies with emphasis on multidisciplinary research that fundamentally alters and transforms manufacturing capabilities, methods and practices. Advanced manufacturing research proposals should address issues related to national prosperity and security, and advancing knowledge to sustain global leadership. Areas of research, for example, include manufacturing systems; materials processing; manufacturing machines; methodologies; and manufacturing across the length scales. Researchers working in the areas of cybermanufacturing systems, manufacturing machines and equipment, materials engineering and processing, and nanomanufacturing are encouraged to transcend and cross domain boundaries. Interdisciplinary, convergent proposals are welcome that bring manufacturing to new application areas, and that incorporate challenges and approaches outside the customary manufacturing portfolio to broaden the impact of America's advanced manufacturing research. Proposals of all sizes will therefore be considered as justified by the project description. Investigators are encouraged to discuss their ideas with AM program directors well in advance of submission at AdvancedManufacturing@nsf.gov.

The Office of Advanced Cyberinfrastructure (OAC) supports translational research and education activities in all aspects of advanced cyberinfrastructure (CI) that lead to deployable, scalable, and sustainable systems capable of transforming science and engineering research. Advanced CI includes the spectrum of computational, data, software, networking, and security resources, tools, and services, along with the computational and data skills and expertise, that individually and collectively can transform science and engineering. OAC supports advanced CI research to address new CI frontiers for discovery leading to major innovations, and supports the development and deployment processes, as well as expert services, necessary for realizing the research CI that is critical to the advancement of all areas of science and engineering research and education.

The Bureau of Democracy, Human Rights, and Labor (DRL) announces a Request for Statements of Interest (RSOI) from organizations interested in submitting Statements of Interest (SOI) for programs that support Internet Freedom. In support of the U.S. International Strategy for Cyberspace, DRL's goal is to protect the open, interoperable, secure, and reliable Internet by promoting fundamental freedoms, human rights, and the free flow of information online through integrated support to civil society for technology, digital safety, policy and advocacy, and applied research programs. DRL invites organizations interested in potential funding to submit SOI applications outlining program concepts that reflect this goal.

The Advanced Manufacturing (AM) program supports the fundamental research needed to revitalize American manufacturing to grow the national prosperity and workforce, and to reshape our strategic industries. The AM program accelerates advances in manufacturing technologies with emphasis on multidisciplinary research that fundamentally alters and transforms manufacturing capabilities, methods and practices. Advanced manufacturing research proposals should address issues related to national prosperity and security, and advancing knowledge to sustain global leadership.

The GO Competition is a series of prize challenges to accelerate the development and comprehensive evaluation of grid software solutions. The first GO Competition, Challenge 1, is an algorithm competition focused on the security-constrained optimal power flow (SCOPF) problem for the electric power sector. Awardees under this FOA will be required to participate in Challenge 1. As described in detail in Appendix A1 to this FOA and on the GO Competition website (https://gocompetition.energy.gov/), Challenge 1 is anticipated to launch in the Fall of 2018. Participation in the GO Competition Challenge 1 will be open to anyone that satisfies the applicable requirements in Rules Document specified on the GO Competition website (https://gocompetition.energy.gov/competition-rules), not just those awarded under ARPA-E DE-FOA-0001952. The purpose of this FOA is to provide grants: (i) to further incentivize and identify innovative research for solution methods applicable to Challenge 1, and (ii) to enable broader diversity in team domain expertise, i.e., to encourage teams to participate that do not traditionally focus on the particular problems that are targeted but otherwise have innovative approaches for this class of mathematical programs. While Challenge 1 focuses on a power systems problem, the Challenge and this FOA target a much broader audience (e.g., those specialized in operations research, applied mathematics, optimization methods and algorithms, controls etc.). Existing grid software was designed for a power grid centered on conventional generation and transmission technologies.

As defined by the DoD, basic research is "systematic study directed toward greater knowledge or understanding of the fundamental aspects of phenomena and of observable facts without specific applications towards processes or products in mind. It includes all scientific study and experimentation directed toward increasing fundamental knowledge and understanding in those fields of the physical, engineering, environmental, and life sciences related to long-term national security needs. It is farsighted high payoff research that provides the basis for technological progress." (DoD 7000.14-R, vol. 2B, chap. 5, para. 050105.B) The DoD's basic research program invests broadly in many scientific fields to ensure that it has early cognizance of new scientific knowledge.

High Intensity Thermal Exchange Through Materials and Manufacturing Process (HITEMMP) Agency Overview: The Advanced Research Projects Agency - Energy (ARPA-E), an organization within the Department of Energy (DOE), is chartered by Congress in the America COMPETES Act of 2007 (P.L. 110-69), as amended by the America COMPETES Reauthorization Act of 2010 (P.L. 111-358) to: "(A) to enhance the economic and energy security of the United States through the development of energy technologies that result in- (i) reductions of imports of energy from foreign sources; (ii) reductions of energy-related emissions, including greenhouse gases; and (iii) improvement in the energy efficiency of all economic sectors; and (B) to ensure that the United States maintains a technological lead in developing and deploying advanced energy technologies." ARPA-E issues this Funding Opportunity Announcement (FOA) under the programmatic authorizing statute codified at 42 U.S.C. § 16538.

The NSF 2026 Idea Machine is a competition to help set the U.S. agenda for fundamental research in science and engineering. Participants can earn prizes and receive public recognition by suggesting the pressing research questions that need to be answered in the coming decade, the next set of "Big Ideas" for future investment by the National Science Foundation (NSF). It's an opportunity for researchers, the public and other interested stakeholders to contribute to NSF's mission to support basic research and enable new discoveries that drive the U.S. economy, enhance national security and advance knowledge to sustain the country's global leadership in science and engineering.

The Pancreatic Cancer Action Network is accepting applications for its 2018 Catalyst Grant program. The program, which aims to encourage and support junior faculty in the pursuit of pancreatic cancer research and establish a career path in the field, provides grants of up to $500,000 over three years to junior investigators who have yet to secure their first significant research funding. Research projects may be basic, translational, clinical, or epidemiological in nature but must have direct applicability and relevance to pancreatic cancer. Grant recipients not only receive financial support for their funded research but also are invited to join the network's Community for Progress, a mentorship program that works to advance the goal of increasing survival rates and improving outcomes for pancreatic cancer patients. To be eligible, applicants must have a doctoral degree (PD, MD, DO, DC, ND, DDS, DVM, ScD, DNS, PharmD, or equivalent) in the biomedical sciences (or in a field applicable to health science research) and not currently be a candidate for a further doctoral degree. In addition, at the start of the grant term on July 1, 2018, applicants must hold a faculty position with the title of assistant professor, instructor, research assistant professor, or the equivalent.

The Information Directorate of the Air Force Research Laboratory (AFRL/RI), Rome Research Site, is soliciting white papers under this announcement for innovative technologies to enable the effective management of information for military operations. Focus: The objective of this BAA is to develop and demonstrate middleware to bridge the tactical and enterprise domains, realizing decentralized IM services built upon client-based protocols for use at the tactical edge that can coexist and interoperate securely with the server-based IM services that are well-suited for deployment in enterprise-scale environments. To improve the exchange of information between enterprise and the tactical edge networks and applications, these services need to be capable of operating in contested/congested environments and be built upon disruption and fault tolerant techniques and technologies. The research and development to be conducted under this BAA is focused on the following: 1) Interoperable hybrid centralized & decentralized IM services designed for mobile operations. 2) Gateways for the exchange of heterogeneous information across disparate networks. 3) Disruption tolerant information preservation, optimized delivery, and synchronization. 4) Demonstration of the utility of these capabilities in operationally relevant environments.

The landscape of jobs and work is changing at unprecedented speed, enabled by advances in computer and engineering technologies such as artificial intelligence and robotics, deeper understanding of societal and environmental change, advances in the learning sciences, pervasive, intelligent, and autonomous systems, and new conceptions of work and workplaces. This technological and scientific revolution presents a historical opportunity to the Nation and its people, in the creation of new industries and occupations, enhanced productivity and quality of work life, and the potential for more people to participate in the workforce, ultimately yielding sustained innovation and global leadership. But, as history teaches, such changes also come with risks. Some risks are immediate, such as jobs lost to automation or demand for skills not met by current educational pathways. Other equally important risks include new security threats, algorithmic biases, unanticipated legal consequences including privacy implications, dependence on technology and erosion of human knowledge and skills, inadequate workplace policies and practices, or undesirable impact on the built environment.

Cyber-physical systems (CPS) are engineered systems that are built from, and depend upon, the seamless integration of computation and physical components. Advances in CPS will enable capability, adaptability, scalability, resiliency, safety, security, and usability that will expand the horizons of these critical systems. CPS technologies are transforming the way people interact with engineered systems, just as the Internet has transformed the way people interact with information. New, smart CPS drive innovation and competition in a range of application domains including agriculture, aeronautics, building design, civil infrastructure, energy, environmental quality, healthcare and personalized medicine, manufacturing, and transportation. Moreover, the integration of artificial intelligence with CPS creates new research opportunities with major societal implications.

The goal of the interagency Smartand Connected Health (SCH): Connecting Data, People and Systems program is to accelerate the development and integration of innovative computer and information scienceand engineering approaches to support the transformation of health and medicine. Approaches that partner technology-based solutions with biomedical and biobehavioral research are supported by multiple agencies of the federal government including the National Science Foundation (NSF) and the National Institutes of Health (NIH). The purpose of this program is to develop next-generation multidisciplinary science that encourages existing and new research communities to focus on breakthrough ideas in a variety of areas of value to health, such as networking, pervasive computing, advanced analytics, sensor integration, privacy and security, modeling of socio-behavioral and cognitive processes and system and process modeling. Effective solutions must satisfy a multitude of constraints arising from clinical/medical needs, barriers to change, heterogeneity of data, semantic mismatch and limitations of current cyberphysical systems and an aging population.Such solutions demand multidisciplinary teams ready to address issues ranging from fundamental science and engineering to medical and public health practice.

The mission of DOE's Fossil Energy R&D Program is to ensure the nation can continue to rely on traditional resources for clean, secure and affordable energy while enhancing environmental protection. The Carbon Capture program focuses on developing technologies to control emissions from either post-combustion units (e.g., pulverized coal) or pre-combustion (e.g., Integrated Gasification Combined Cycle, or IGCC). First Generation technologies (i.e. those that are currently being demonstrated or that are commercially available) exist, and Second Generation Technologies (i.e., those that include technology components currently in R&D and are expected to be ready for demonstration in the 2020-2025 timeframe) have shown potential for improvement towards an economic goal for cost of capture at less than $40/tonne, but are still cost prohibitive for broad deployment to the existing coal fleet. For Fiscal Year (FY) 2018, the Carbon Capture Program will solicit applications under this FOA to develop technologies in the area of pre-combustion carbon capture. Approaches that look at either hydrogen (H2) separation or carbon dioxide (CO2) separation will be accepted. The carbon capture technologies developed through this FOA will have direct application to coal gasification processes where coal derived synthesis gas or hydrogen are produced. Additionally, because gasification technology is often used to produce industrial chemicals, the technologies developed through this FOA will also be directly applicable to industrial gasifiers.

The program is focused on multidisciplinary research efforts where more than one traditional discipline interacts to provide rapid advances in scientific areas of interest to the DoD. As defined in the DoD Financial Management Regulation: Basic research is systematic study directed toward greater knowledge or understanding of the fundamental aspects of phenomena and of observable facts without specific applications towards processes or products in mind. It includes all scientific study and experimentation directed toward increasing fundamental knowledge and understanding in those fields of the physical, engineering, environmental, and life sciences related to long-term national security needs.

The MURI program supports basic research in science and engineering at U.S. institutions of higher education (hereafter referred to as "universities") that is of potential interest to DoD. The program is focused on multidisciplinary research efforts where more than one traditional discipline interacts to provide rapid advances in scientific areas of interest to the DoD. As defined in the DoD Financial Management Regulation: Basic research is systematic study directed toward greater knowledge or understanding of the fundamental aspects of phenomena and of observable facts without specific applications towards processes or products in mind. It includes all scientific study and experimentation directed toward increasing fundamental knowledge and understanding in those fields of the physical, engineering, environmental, and life sciences related to long term national security needs. It is farsighted high payoff research that provides the basis for technological progress (DoD 7000.14-R, vol. 2B, chap. 5, para. 050201.B). DoD's basic research program invests broadly in many specific fields to ensure that it has early cognizance of new scientific knowledge.

The Global Engagement Center (GEC), an interagency entity within the U.S. Department of State, invites organizations that can implement programming to counter foreign state and non-state propaganda and disinformation efforts aimed at undermining United States national security interests to submit applications by April 11, 2018. All submissions or applications will be reviewed against the evaluation criteria outlined below. GEC expects to make multiple awards with a floor of $200,000 and a ceiling of $500,000 for each, constituting a planned total award volume of approximately $5,000,000. GEC reserves the right to award more or less funding or no funding at all as it deems in the best interest of the government. U.S.-based and foreign non-profit and non-governmental organizations (NGO), public international organizations (PIO), media outlets, for-profit entities, and institutions of higher education are eligible to apply by submitting an application as described in this announcement.

A well-prepared, innovative science, technology, engineering, and mathematics (STEM) workforce is crucial to the Nation's prosperity and security. Future generations of STEM professionals are a key sector of this workforce, especially in the critical scientific areas described in the Big Ideas for Future NSF Investments. To accelerate progress in these areas, the next generation of STEM professionals will need to master new knowledge and skills, collaborate across disciplines, and shape the future of the human-technology interface in the workplace. As a result, NSF recognizes the need to support development of and research on effective educational approaches that can position the future STEM workforce to make bold advances in these Big Ideas.