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Although invention and proof-of-concept testing of new technologies are a key component of the BRAIN Initiative, to achieve their potential these technologies must also be optimized through feedback from end-users in the context of the intended experimental use. This seeks applications for the optimization of existing and emerging technologies and approaches that have potential to address major challenges associated with recording and manipulating neural activity, at or near cellular resolution, at multiple spatial and temporal scales, in any region and throughout the entire depth of the brain. This FOA is intended for the iterative refinement of emergent technologies and approaches that have already demonstrated their transformative potential through initial proof-of-concept testing, and are appropriate for accelerated development of hardware and software while scaling manufacturing techniques towards sustainable, broad dissemination and user-friendly incorporation into regular neuroscience practice. Proposed technologies should be compatible with experiments in behaving animals, and should include advancements that enable or reduce major barriers to hypothesis-driven experiments. Technologies may engage diverse types of signaling beyond neuronal electrical activity for large-scale analysis, and may utilize any modality such as optical, electrical, magnetic, acoustic or genetic recording/manipulation. Applications that seek to integrate multiple approaches are encouraged. Applications are expected to integrate appropriate domains of expertise, including where appropriate biological, chemical and physical sciences, engineering, computational modeling and statistical analysis.

This NOFO will sustain and continue progress made through the previous CDC SI Cooperative Agreement. The purpose of this NOFO is to promote evidence-based decision making for an AIDS-Free generation by monitoring data quality at the site-level and collecting, analyzing and disseminating data at all levels. NOFO objectives are to: (1) improve capacity of M&E systems to oversee data quality and data use for decision making (including capacity building of M&E staff); (2) enhance district-led and nationally supported evidence-based programming (triangulating data from multiple data sources); (3) improve the understanding of HIV burden, incidence, loss to follow-up, linkages, and referral services across interventions (95-95-95) and facilities; (4) support regular updates to DHIS2 and electronic registers (including use of unique identifiers) to reflect changes to MOH and/or PEPFAR indicators; and (5) improve and/or develop interoperability of DHIS2 with other data systems in country.

The National Science Foundation (NSF) seeks to further develop and nurture a national innovation ecosystem that builds upon fundamental research to guide the output of scientific discoveries closer to the development of technologies, products, processes and services that benefit society. The goal of the program is to dramatically reduce the period of time necessary to bring a promising idea from its inception to widespread implementation. Through this solicitation, NSF is seeking to expand and sustain the network of Innovation Corps (I-CorpsTM) (hereinafter I-Corps) Nodes that work cooperatively to support the development of innovations that will benefit society. NSF plans to build upon the established National Innovation Network (consisting of I-Corps Nodes and Sites) to further support the needs for innovation research, education and training. The interconnected nodes of the network are expected to be diverse in research areas, resources, tools, programs, capabilities, and geographic locations - providing the network with the flexibility to grow or reconfigure as needs arise.

The goal of the Sensing, Learning, Autonomy, and Knowledge Engineering (SLAKE) program is to advance Air Force sensing capabilities by employing diverse sensor processing results at a representational or product level that is abstracted from the direct sensing output yet retains crucial information and corresponding uncertainties. Key research areas under SLAKE include development of sensor product representations suitable for efficient storage, efficient communication, and efficient resource allocation; robust conversion of sensor processing output to novel representation formats; accurate characterization of sensing uncertainties; rigorous incorporation of sensing uncertainties within novel algorithms for sensor resource management, task allocation, and information fusion; development and employment of virtual environments suitable for exercising specific algorithms and for analyzing specific system concepts; and sustained, efficient descriptions of mission context and mission operating environment. In support of technology maturation and transition, SLAKE also includes small unmanned aerial system (SUAS) integration and operation, advanced demonstration and validation.

The IMEE program supports fundamental, multidisciplinary research on the impact of hazards and disasters upon civil infrastructure and society. The program is focused upon research on the mitigation of, preparedness for, response to, and recovery from multi-hazard disasters. Community and societal resilience and sustainability are important topics within the research portfolio of IMEE. The program is deeply multidisciplinary, integrating multiple perspectives, methods and results from diverse areas in engineering, social and natural sciences, and computing. Among these are civil, mechanical, transportation and system engineering; sociology, cognitive science and psychology, economics, geography, political science and urban planning; geology, biology and meteorology; and applied computing. Methodological innovations that span multiple, diverse disciplines are strongly encouraged.

This Broad Agency Announcement (BAA) enhances the DPA Title III effort by providing to potential offerors information and procedures necessary to identify domestic industrial base projects, potentially meeting the DPA Title III criteria, by using the white paper and proposal formats. Project Announcements for a specific domestic industrial base shortfall, issued subsequent to this BAA, is the main method to initiate a call for white papers, leading to an evaluation and potential request for full proposals. Project Announcement #1 is included with this initial posting of the BAA. Consistent with the law, the DPA Title III Program has derived three broad Focus Areas for potential projects. The Focus Areas are: Sustainment of Critical Production, Commercialization of Research and Development Investments and Scaling of Emerging Technologies.

This notice solicits applications to support a Telehealth Center of Excellence. The primary purpose of this program is to examine the efficacy of telehealth[1] services in rural and urban areas. The Telehealth Center of Excellence will be located in a public academic medical center that: Has a successful telehealth program with a high annual volume of telehealth visits; Has an established reimbursement structure that allows telehealth services to be financially self-sustaining; and Has established programs that provide telehealth services in medically underserved areas with high chronic disease prevalence and high poverty rates. The Telehealth Center of Excellence will serve as a national clearinghouse for telehealth research and resources, including technical assistance. To achieve that goal, the Telehealth Center of Excellence should have substantial experience operating a telehealth program that offers a broad range of clinical services and has experience demonstrating how their efforts have improved access to care and enhanced health outcomes for their patients. [1] The Office for the Advancement of Telehealth defines Telehealth as the use of electronic information and telecommunication technologies to support and promote long-distance clinical health care, patient and professional health-related education, public health, and health administration. Technologies include video conferencing, the internet, store-and-forward imaging, streaming media, and terrestrial and wireless communications.

The Sloan and Ford Foundations would like to fund a set of research projects to further study these dynamics, with an eye toward better understanding the economics, maintenance and sustainability of digital infrastructure.

The Advanced Manufacturing (AM) program supports the fundamental research needed to revitalize American manufacturing to grow the national prosperity and workforce, and to reshape our strategic industries. The AM program accelerates advances in manufacturing technologies with emphasis on multidisciplinary research that fundamentally alters and transforms manufacturing capabilities, methods and practices. Advanced manufacturing research proposals should address issues related to national prosperity and security, and advancing knowledge to sustain global leadership. Areas of research, for example, include manufacturing systems; materials processing; manufacturing machines; methodologies; and manufacturing across the length scales. Researchers working in the areas of cybermanufacturing systems, manufacturing machines and equipment, materials engineering and processing, and nanomanufacturing are encouraged to transcend and cross domain boundaries. Interdisciplinary, convergent proposals are welcome that bring manufacturing to new application areas, and that incorporate challenges and approaches outside the customary manufacturing portfolio to broaden the impact of America's advanced manufacturing research. Proposals of all sizes will therefore be considered as justified by the project description. Investigators are encouraged to discuss their ideas with AM program directors well in advance of submission at AdvancedManufacturing@nsf.gov.

This funding opportunity announcement (FOA) encourages grant applications for national Biomedical Technology Research Resources (BTRR). These Resources conduct research and development of new or improved technologies driven by the needs of basic, translational, and clinical researchers. The Resources are charged to make their technologies available to the research community in a sustainable manner, to provide user training, and to disseminate the Resources technologies and experimental results. Resources should be at the leading edge of their field with respect to both technology development and engagement of the relevant research community. New applicants are strongly encouraged to submit a pre-application in response to PAR-17-315 The pre-application process provides feedback on whether the proposed technology development is appropriate for the NIGMS BTRR program, and the potential competitiveness of a full application.

The mobile or wireless solution must have the potential to solve a problem in the areas of access to education, health, access to communication, economic development, and the environment/disaster relief. The project must be at a stage of research where an advanced prototype or field/market test can occur during the award period, and the technology should have the potential for replication and large-scale impact. Applicants also should have a business plan or basic framework for financial sustainability and rollout.

The Nation's advanced research cyberinfrastructure (CI) ecosystem catalyzes discovery and innovation across all areas of science and engineering (S&E) research and education. The increasingly complex and rapidly evolving S&E landscape requires an agile, integrated, robust, trustworthy, and sustainable CI ecosystem that will drive new thinking and transformative discoveries in all areas of research and education. The success of this vision depends on the ability of the research community to be able to easily and effectively access and use state-of-the-art research CI resources and services in a timely way. This, in turn, drives a set of requirements on the development, operation, and evolution of the CI ecosystem. First, research CI resources and services must be designed to leverage and drive innovations, and they must be user-centric and interoperable to enable the efficient, flexible end-to-end discovery pathways that are increasingly essential for the conduct of research. Second, the information, expertise, and services needed to maximally utilize the CI ecosystem must be disseminated broadly and concertedly to the research community. The NSF Cyberinfrastructure Centers of Excellence (CI CoE) Program aims to realize the above vision by supporting hubs of expertise and innovation targeting specific areas, aspects, or stakeholder communities of the research CI ecosystem.

Artificial Intelligence (AI) has advanced tremendously and today promises personalized healthcare; enhanced national security; improved transportation; and more effective education, to name just a few benefits. Increased computing power, the availability of large datasets and streaming data, and algorithmic advances in machine learning (ML) have made it possible for AI development to create new sectors of the economy and revitalize industries. Continued advancement, enabled by sustained federal investment and channeled toward issues of national importance, holds the potential for further economic impact and quality-of-life improvements.

The OFRN Round 5 Sustaining Ohio's Aeronautical Readiness and Innovation in the Next Generation (SOARING) Opportunity Announcement is focused on expanding Ohio's research and development capabilities across the state's academic institutions and business in support of Ohio-based federal partner needs, which ultimately promotes Ohio's economic growth.  OFRN Round 5 Areas of Interest (AOIs) include topics in Unmanned Aerial Systems (UAS), Artificial Intelligence, Human Factors, Data Analytics, Space Commercialization, Quantum Communications and Advanced Power Systems.  This announcement seeks to leverage Ohio's unique research capabilities and its federal partner's expertise to accelerate technology development and innovation by increasing collaboration across government, academic, and industry organizations. 

The Core Infrastructure Fund (CIF) strives to uphold and increase capacity for individuals, organizations, and companies working to fortify the foundational components of demonstrably important technology relied upon by people in repressive countries. Ideal applications are: open in nature, collaborative, promote a broader understanding of existing challenges and limitations, are preemptive in approach, and/or exist at the core of the Internet's ecosystem. Common applicants come from the community of developers and organizers working on open-source projects recognized as critical dependencies of one or more active platforms or tools strengthening Internet freedom and digital security. Ideal applications for this fund focus on supporting: Key developers or organizers so they can work full time on crucial core efforts in need of additional support; New developers or organizers focused on improving security standards, quality assurance, and best practices within core infrastructure projects; Developers, authors, or organizers drafting or promoting digital security and civil society needs within standards and protocols; Researchers exploring new methods of circumvention that would improve the resiliency of widely utilized tools; Specific outcomes, such as the necessary maintenance and upgrades to existing open source projects (database, hosting, or other tool migration; rewriting test suites; major new features); Efforts that make existing projects more accessible and easier to contribute to (ex. documentation, tool migration, refactoring code, testing); Efforts that develop new or evolve existing organizational and governance structures and sustainability models beyond work-for-hire; Efforts that increase the understanding and awareness of relevant actors in this space, their roles, and how they contribute to maintaining the Internet's core ecosystem;

This Funding Opportunity Announcement (FOA) aims to support research to strengthen the healthcare response to Coronavirus Disease 2019 (COVID-19) caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and future public health emergencies, including pandemics. While research related to the direct clinical effects of COVID-19 are supported by other funding opportunities, the purpose of this funding opportunity is to focus on the role and impact of digital health interventions [e.g., mobile health (mhealth), telemedicine and telehealth, health information technology (IT), and wearable devices] to address access, reach, delivery, effectiveness, scalability and sustainability of health assessments and interventions for secondary effects (e.g., behavioral health or self-management of chronic conditions) that are utilized during and following the pandemic, particularly in populations who experience health disparities and vulnerable populations.

The RISA program supports the development of knowledge, expertise, and abilities of decision-makers to plan and prepare for climate variability and change. Through regionally-focused and interdisciplinary research and engagement teams, RISA builds and expands the Nation's capacity to adapt and become resilient to extreme weather events and climate change. RISA teams accomplish this through co-developed applied research and partnerships with public and private communities. A central tenet of the RISA program is that learning about climate adaptation and resilience is facilitated by and sustained across a wide range of experts, practitioners, and the public. As such, the RISA program supports a network of people, prioritizing wide participation in learning by doing, learning through adapting, and managing risk with uncertain information. Early decades of the program focused on understanding the use of climate information at regional scales (e.g., through experimental seasonal outlooks), improving predictions and scenarios, building capacity for drought early warning, and advancing the science of climate impact assessments. More recently, emphasis has shifted to address the growing urgency to advance approaches that tackle the complex societal issues surrounding adaptation planning, implementation, and building community resilience. To do so, RISA continues to prioritize collaborative approaches that incorporate multiple knowledge sources and integrate social, physical, and natural science, resulting in long-term support of and increased capacity for communities.

Through its CISE Research Infrastructure (CRI) program (NSF 14-593 - http://www.nsf.gov/publications/pub_summ.jsp?ods_key=nsf14593), the NSF Directorate for Computer and Information Science and Engineering (CISE) supports world-class research infrastructure enabling focused research agendas in computer and information science and engineering. The CRI program funds both the creation of new infrastructure as well as the enhancement of existing infrastructure.

ecoTech™ Grants were created to combat the notion that students needed to choose between "the screen" or "the green" and to encourage educators and students to explore the role technology can play in designing and implementing solutions to some of our most pressing environmental challenges. We believe that technology can present innovative ways to address environmental challenges - and that when dealing with digital natives, we do ourselves a disservice by asking them to unplug. Originally developed in partnership with the Ray C. Anderson Foundation and now funded with ongoing support from Voya Financial Foundation, ecoTech™ Grants are specifically offered to engage children in inquiry-based, STEM-related projects that leverage technology and/or use nature-based design to address environmental problems in local communities. Examples of previous ecoTech™ Grant funded projects have involved: the integration of robotics and sensors to explore water bodies, collect data, and organize clean-ups; the development of aquaponic and hydroponic systems using arduinos and remote sensing; renewable energy design challenges; biotechnology research; nature-based design applications; and many others.

This Funding Opportunity Announcement (FOA) seeks clinical research on self-management interventions and technologies that improve health and quality of life in persons needing assistance to optimize and maintain existing functional capabilities, prevent/delay disabilities and navigate their environment. The research focus encompasses maintenance/restorative care that can be tailored to individuals existing functional abilities and interests and is intended to enhance physical, sensory, motor, and mental capabilities. Of particular interest is research designed to maintain functional capabilities in such conditions as cardiac and respiratory insufficiency, movement impairment associated with arthritis, chronic back pain, stroke, and other physical or cognitive disabilities.