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CISE's Division of Computer and Network Systems (CNS) supports research and education projects that develop new knowledge in two core programs: Computer Systems Research (CSR) program; and Networking Technology and Systems (NeTS) program.

USAID has a long history of engaging higher education institutions (HEIs) to achieve development objectives. Together with HEIs, the U.S. Global Development Lab partners with USAID colleagues, other federal agencies, NGOs, and the private sector to increase the scientific knowledge and evidence directed toward addressing USAID's development priorities and improving policy and programming decisions.

CISE's Division of Computer and Network Systems (CNS) supports research and education projects that develop new knowledge in two core programs: -Computer Systems Research (CSR) program; -Networking Technology and Systems (NeTS) program.

The RCN program provides opportunities to foster new collaborations, including international partnerships, and address interdisciplinary topics. Innovative ideas for implementing novel networking strategies, collaborative technologies, training, broadening participation, and development of community standards for data and meta-data are especially encouraged. RCN awards are not meant to support existing networks; nor are they meant to support the activities of established collaborations. RCN awards also do not support primary research.

Under this umbrella, NSF and the National Institute of Information and Communications Technology (NICT) of Japan have agreed to embark on a collaborative research program to address compelling research challenges associated with enabling trustworthy networks supporting the Internet of Things (IoT) and cyber-physical systems (CPS). This NSF solicitation parallels an equivalent NICT solicitation. Proposals submitted under this solicitation must describe joint research with counterpart Japanese investigators who are requesting funding separately under the NICT solicitation.

CISE's Division of Information and Intelligent Systems (IIS) supports research and education projects that develop new knowledge in three core programs: The Cyber-Human Systems (CHS) program; The Information Integration and Informatics (III) program; and The Robust Intelligence (RI) program

Secretary of the Air Force Heather Wilson announced in September 2017 inception of the "S&T Strategy 2030" study. The study's objective is to update the Air Force methods for conducting research and development (R&D) to meet the projected national security challenges of 2030. Secretary Wilson appointed the Air Force Research Laboratory (AFRL) to lead this strategy development.The Air Force's goals for the study are: 1. Evaluate technical approaches and focus areas to advance the Air Force's mission through R&D; and 2. Improve Air Force processes and organizational structures to manage early stage research.

I2O seeks unconventional approaches that are outside the mainstream, challenge accepted assumptions, and have the potential to radically change established practice. Proposed research should investigate innovative approaches that enable revolutionary advances in science, devices, or systems.

The Partnerships for Innovation: Building Innovation Capacity (PFI:BIC) program supports academe-industry partnerships which are led by an interdisciplinary academic research team collaborating with a least one industry partner. In this program, there is a heavy emphasis on the quality, composition, and participation of the partners, including their appropriate contributions. These partnerships focus on the integration of technologies into a specified human-centered service system with the potential to achieve transformational benefits, satisfying a real need by making an existing service system smart(er) or by spurring the creation of an entirely new smart service system. The selected service system should function as a test bed.