The purpose of this specific FOA is to solicit applications to develop and implement a Knowledge Management Center (KMC) for the Illuminating the Druggable Genome (IDG) Program. The KMC will house, organize, and share metadata and data by accruing and abstracting data and information available in primary literature, databases, and other resources around the world and deploy an integrated informatics solution. However, any proposed human curation efforts will initially focus only on illuminating three major protein families of the IDG project: non-olfactory G protein-coupled receptors, ion channels and protein kinases. The KMC will identify and scientifically justify the data and resources it proposes to accrue that will enable the biomedical community to easily identify and prioritize protein targets within any gene family to study further. The KMC awardee will be expected to interact and collaborate with all future awardees of the IDG Program, the IDG Consortium, and, future awardees of the IDG CEITs.
The PRMRP Investigator-Initiated Research Award (IIRA) is intended to support studies that
will make an important contribution toward research and/or patient care for a disease or
condition related to at least one of the FY19 PRMRP Topic Areas.
The rationale for a research idea may be derived from a laboratory discovery, population-based
studies, a clinician's first-hand knowledge of patients, or anecdotal data. Applications must
include relevant data that support the rationale for the proposed study. These data may be
unpublished or from the published literature
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