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The Pancreatic Cancer Action Network-AACR Innovative Grants represent a joint effort to promote and support innovative pancreatic cancer research. They aim to spur creative and cutting-edge ideas and approaches in pancreatic cancer research, including those successful in other areas of cancer that have justifiable promise for pancreatic cancer. The research proposed for funding may be basic, translational, clinical or epidemiological in nature and must have direct applicability and relevance to pancreatic cancer. These grants are available to full time, independent junior and senior investigators, including those with experience in other areas of cancer or biomedical/health science research who have promising ideas and approaches that can be applied to pancreatic cancer research.

The Pancreatic Cancer Action Network-AACR Career Development Awards represent a joint effort to encourage and support junior faculty who are in the first five years of a faculty appointment (at the start of the grant term) to conduct pancreatic cancer research and establish successful career paths in this field. The research proposed for funding may be basic, translational, clinical or epidemiological in nature and must have direct applicability and relevance to pancreatic cancer.

The purpose of the BRAG program is to support the generation of new information that will assist Federal regulatory agencies in making science-based decisions about the effects of introducing into the environment genetically engineered organisms (GE), including plants, microorganisms (including fungi, bacteria, and viruses), arthropods, fish, birds, mammals and other animals excluding humans. Investigations of effects on both managed and natural environments are relevant. The BRAG program accomplishes its purpose by providing Federal regulatory agencies with scientific information relevant to regulatory issues. 

This Funding Opportunity Announcement (FOA), issued by the National Institute on Drug Abuse (NIDA), invites grant applications that propose longitudinal cohort studies to address emerging and/or high priority research on HIV/AIDS and substance abuse. This FOA will support the development and maintenance of new cohorts or the expansion of existing cohorts to address the natural and treated history of HIV infection in at-risk populations where substance use is a central factor. The intent of the FOA is to provide a strong resource platform for current and future collaborative efforts with other investigators to address emerging questions related to HIV infection, prevention, and treatment in the context of substance abuse, as well as to foster the creativity and efficiency of investigatorinitiated research goals.

Through its Science of Hope and Optimism Funding Initiative program, the association will award two-year grants of up to $250,000 for research projects that use a variety of methods to explore the nature of hope and optimism. Priority will be given to projects in cognitive, developmental, personality, health, and social psychology, as well as sociology. Interdisciplinary teams that include members from cognate areas - e.g., cognitive science, anthropology, nursing, and biology - are encouraged.

Two $55,000 pilot grants will be available to investigators conducting research on Pitt Hopkins Syndrome (PTHS). Pitt Hopkins Syndrome is due to a deficiency in the TCF4 gene and is characterized by severe intellectual disability and developmental delay. Other symptoms include episodic hyperventilation and/or breath-holding (55%-60%), recurrent seizures/epilepsy (40%-50%), gastrointestinal issues, and distinctive facial features. The Pitt Hopkins Research Foundation would like to focus this research on finding therapeutics and a cure for this debilitating syndrome and are not in interested in natural history studies.

This Funding Opportunity Announcement (FOA) issued by the Office of Behavioral and Social Sciences Research (OBSSR) and the National Cancer Institute (NCI), the National Heart, Lung, and Blood Institute (NHLBI), the National Institute on Aging (NIA), the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Institute of Biomedical Imaging and Bioengineering (NIBIB), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the National Institute of Dental and Craniofacial Research (NIDCR), the National Institute of Environmental Health Sciences (NIEHS), the National Institute of General Medical Sciences (NIGMS), the National Institute of Mental Health (NIMH), and the National Institute of Nursing Research (NINR) at the National Institutes of Health, encourages Research Project Grant (R01) applications from institutions/organizations that propose to develop basic and applied projects utilizing systems science methodologies relevant to human behavioral and social sciences and health. This FOA is intended to encourage a broader scope of topics to be addressed with systems science methodologies, beyond those encouraged by existing open FOAs. Research projects applicable to this FOA are those that are either applied or basic in nature (including methodological development), have a human behavioral and/or social science focus, and feature systems science methodologies

The Long Term Research in Environmental Biology (LTREB) Program supports the generation of extended time series of data to address important questions in evolutionary biology, ecology, and ecosystem science. Research areas include, but are not limited to, the effects of natural selection or other evolutionary processes on populations, communities, or ecosystems; the effects of interspecific interactions that vary over time and space; population or community dynamics for organisms that have extended life spans and long turnover times; feedbacks between ecological and evolutionary processes; pools of materials such as nutrients in soils that turn over at intermediate to longer time scales; and external forcing functions such as climatic cycles that operate over long return intervals.The Program intends to support decadal projects. Funding for an initial, 5-year period requires submission of a preliminary proposal and, if invited, submission of a full proposal that includes a 15-page project description. 

The Division of Environmental Biology (DEB) supports fundamental research on populations, species, communities, and ecosystems. Scientific emphases range across many evolutionary and ecological patterns and processes at all spatial and temporal scales. Areas of research include biodiversity, phylogenetic systematics, molecular evolution, life history evolution, natural selection, ecology, biogeography, ecosystem structure, function and services, conservation biology, global change, and biogeochemical cycles. Research on organismal origins, functions, relationships, interactions, and evolutionary history may incorporate field, laboratory, or collection-based approaches; observational or manipulative experiments; synthesis activities; as well as theoretical approaches involving analytical, statistical, or computational modeling.

The new National Ocean Policy calls for actions to improve understanding of and capacity to respond to ocean acidification, recognizing the potential adverse impacts of an acidifying sea upon marine ecosystems. The effects of ocean acidification could significantly affect strategies for developing practices towards the sustainability of ocean resources. Basic research concerning the nature, extent and impact of ocean acidification on oceanic environments in the past, present and future is required. Research challenges include: Understanding the geochemistry and biogeochemistry of ocean acidification; Understanding how ocean acidification interacts with biological, chemical and physical processes at the organismal level, and how such interactions impact the structure and function of ecosystems, e.g. through life histories, adaptive evolution, food webs, biogeochemical cycling, and interactions with other changes in the ocean (e.g., temperature, stratification, circulation patterns); and Understanding how the earth system history informs our understanding of the effects of ocean acidification on the present day and future ocean. The Ocean Acidification program is in its fifth and anticipated last year of competition. We expect this to be the last solicitation specifically targeting Ocean Acidification.

The Biomaterials program supports fundamental materials research related to (1) biological materials, (2) biomimetic, bioinspired, and bioenabled materials, (3) synthetic materials intended for applications in contact with biological systems, and (4) the processes through which nature produces biological materials.  Projects are typically interdisciplinary and may encompass scales from the nanoscopic to the bulk.  They may involve characterization, design, preparation, and modification; studies of structure-property relationships and interfacial behavior; and combinations of experiment, theory, and/or simulation.  The emphasis is on novel materials design and development and discovery of new phenomena.

 Program supports the generation of extended time series of data to address important questions in evolutionary biology, ecology, and ecosystem science. Research areas include, but are not limited to, the effects of natural selection or other evolutionary processes on populations, communities, or ecosystems; the effects of interspecific interactions that vary over time and space; population or community dynamics for organisms that have extended life spans and long turnover times; feedbacks between ecological and evolutionary processes; pools of materials such as nutrients in soils that turn over at intermediate to longer time scales; and external forcing functions such as climatic cycles that operate over long return intervals. 

The Division of Environmental Biology (DEB) supports fundamental research on populations, species, communities, and ecosystems. Scientific emphases range across many evolutionary and ecological patterns and processes at all spatial and temporal scales. Areas of research include biodiversity, phylogenetic systematics, molecular evolution, life history evolution, natural selection, ecology, biogeography, ecosystem structure, function and services, conservation biology, global change, and biogeochemical cycles. Research on organismal origins, functions, relationships, interactions, and evolutionary history may incorporate field, laboratory, or collection-based approaches; observational or manipulative experiments; synthesis activities; as well as theoretical approaches involving analytical, statistical, or computational modeling.

The goal of this Funding Opportunity Announcement (FOA) is to support innovative research focused on understanding the molecular and cellular mechanisms underlying the heterogeneity and multifactorial nature of Alzheimer's disease (AD) with the potential to create new or challenge existing scientific paradigms. This FOA encourages individual or collaborative research projects that propose innovative approaches to understand the complex biology of AD aimed to fill critical knowledge gaps.

The Division of Environmental Biology (DEB) supports fundamental research on populations, species, communities, and ecosystems. Scientific emphases range across many evolutionary and ecological patterns and processes at all spatial and temporal scales. Areas of research include biodiversity, phylogenetic systematics, molecular evolution, life history evolution, natural selection, ecology, biogeography, ecosystem structure, function and services, conservation biology, global change, and biogeochemical cycles

The Division of Environmental Biology (DEB) supports fundamental research on populations, species, communities, and ecosystems. Scientific emphases range across many evolutionary and ecological patterns and processes at all spatial and temporal scales. Areas of research include biodiversity, phylogenetic systematics, molecular evolution, life history evolution, natural selection, ecology, biogeography, ecosystem structure, function and services, conservation biology, global change, and biogeochemical cycles. Research on organismal origins, functions, relationships, interactions, and evolutionary history may incorporate field, laboratory, or collection-based approaches; observational or manipulative experiments; synthesis activities; as well as theoretical approaches involving analytical, statistical, or computational modeling.

The GEOMM program supports fundamental research on the mechanical and engineering properties of geologic materials including natural, mechanically stabilized, and biologically or chemically modified soil and rock. The program also addresses hydraulic, biological, chemical and thermal processes that affect the behavior of geologic materials. Research at the micro-scale on soil-structure interaction and liquefaction are included in the scope of this program. Support is provided for theoretical studies, constitutive and numerical modeling, laboratory, centrifuge, and field testing. Cross-disciplinary and international collaborations are encouraged.

The U.S. Department of Agriculture (USDA) established the  Agriculture and Food Research Initiative (AFRI) under which the Secretary of Agriculture may make competitive grants for fundamental and applied research, education, and extension to address food and agricultural sciences (as defined under section 1404 of the National  Agricultural Research, Extension, and Teaching Policy Act of 1977 (NARETPA) (7 U.S.C. 3103)), as amended, in six priority areas. The six priority areas include: 1) plant health and production and plant products; 2) animal health and production and animal products; 3) food  safety, nutrition, and health; 4) renewable energy, natural resources, and environment; 5) agriculture systems and technology; and 6) agriculture economics and rural communities. 

The Science of Science & Innovation Policy (SciSIP) program supports research designed to advance the scientific basis of science and innovation policy. Research funded by the program thus develops, improves and expands models, analytical tools, data and metrics that can be applied in the science policy decision making process. For example, research proposals may develop behavioral and analytical conceptualizations, frameworks or models that have applications across a broad array of SciSIP challenges, including the relationship between broader participation and innovation or creativity. Proposals may also develop methodologies to analyze science and technology data, and to convey the information to a variety of audiences. Researchers are also encouraged to create or improve science and engineering data, metrics and indicators reflecting current discovery, particularly proposals that demonstrate the viability of collecting and analyzing data on knowledge generation and innovation in organizations. Among the many research topics supported are:examinations of the ways in which the contexts, structures and processes of science and engineering research are affected by policy decision, the evaluation of the tangible and intangible returns from investments in science and from investments in research and development, the study of structures and processes that facilitate the development of usable knowledge, theories of creative processes and their transformation into social and economic outcomes, the collection, analysis and visualization of new data describing the scientific and engineering enterprise. The SciSIP program invites the participation of researchers from all of the social, behavioral and economic sciences as well as those working in domain-specific applications such as chemistry, biology, physics, or nanotechnology. The program welcomes proposals for individual or multi-investigator research projects, doctoral dissertation improvement awards, conferences, wo

The Long Term Research in Environmental Biology (LTREB) Program supports the generation of extended time series of data to address important questions in evolutionary biology, ecology, and ecosystem science. Research areas include, but are not limited to, the effects of natural selection or other evolutionary processes on populations, communities, or ecosystems; the effects of interspecific interactions that vary over time and space; population or community dynamics for organisms that have extended life spans and long turnover times; feedbacks between ecological and evolutionary processes; pools of materials such as nutrients in soils that turn over at intermediate to longer time scales; and external forcing functions such as climatic cycles that operate over long return intervals.