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The Division of Mathematical Sciences in the Directorate for Mathematical and Physical Sciences at the National Science Foundation and the National Institute of General Medical Sciences at the National Institutes of Health plan to support research in mathematics and statistics on questions in the biological and biomedical sciences. Both agencies recognize the need and urgency for promoting research at the interface between the mathematical sciences and the life sciences. This competition is designed to encourage new collaborations, as well as to support existing ones.

The Division of Mathematical Sciences (DMS)in the Directorate for Mathematical and Physical Sciences (MPS) at the National Science Foundation (NSF)and the National Institute of General Medical Sciences (NIGMS) at the National Institutes of Health (NIH)plan to support research in mathematics and statistics on questions in the biological and biomedical sciences. Both agencies recognize the need for promoting research at the interface between the mathematical sciences and the life sciences. This program is designed to encourage new collaborations, as well as to support existing ones.

The Division of Mathematical Sciences (DMS) in the Directorate for Mathematical and Physical Sciences (MPS) at the National Science Foundation (NSF) and the National Institute of General Medical Sciences (NIGMS) at the National Institutes of Health (NIH) plan to support fundamental research in mathematics and statistics necessary to answer questions in the biological and biomedical sciences. Both agencies recognize the need to promote research at the interface between mathematical and life sciences. This program is designed to encourage new collaborations, as well as to support innovative activities by existing teams.

The Mathematical Biology Program supports research in areas of applied and computationalmathematics with relevance to the biological sciences. Successful proposals are mathematically innovative and address challenging problems of interest to members of the biological community. Some projects of interest to the Mathematical Biology Program may include development of mathematical concepts and tools traditionally seen in other disciplinary programs within the Division of Mathematical Sciences, e.g., topology, probability, statistics, computational mathematics, etc.

The Mathematical Biology Program supports research in areas of applied and computationalmathematics with relevance to the biological sciences. Successful proposals are mathematically innovative and address challenging problems of interest to members of the biological community. Some projects of interest to the Mathematical Biology Program may include development of mathematical concepts and tools traditionally seen in other disciplinary programs within the Division of Mathematical Sciences, e.g., topology, probability, statistics, computational mathematics, etc. 

The Division of Mathematical Sciences (DMS) in the Directorate for Mathematical and Physical Sciences (MPS) at the National Science Foundation (NSF) and the National Institute of General Medical Sciences (NIGMS) at the National Institutes of Health (NIH) plan to support fundamental research in mathematics and statistics necessary to answer questions in the biological and biomedical sciences. Both agencies recognize the need to promote research at the interface between mathematical and life sciences. This program is designed to encourage new collaborations, as well as to support innovative activities by existing teams.

The Division of Mathematical Sciences (DMS)in the Directorate for Mathematical and Physical Sciences (MPS) at the National Science Foundation (NSF)and the National Institute of General Medical Sciences (NIGMS) at the National Institutes of Health (NIH)plan to support fundamental research in mathematics and statistics necessary to answer questions in the biological and biomedical sciences. Both agencies recognize the need to promote research at the interface between mathematical and life sciences. This program is designed to encourage new collaborations, as well as to support innovative activities by existing teams.

TRANSLATIONAL MEDICINE AND THERAPEUTICS: The goal of the PhRMA Foundation's Translational Medicine and Therapeutics Program is to promote the development and use of experimental and computational methods in an integrative approach towards clinical needs in diagnosis, treatment and prevention. This can involve enhanced understanding of human biological and disease processes but requires a strong translational component. This program will support the concepts of Translational Medicine and Therapeutics as defined by the Foundation: "Translational medicine and therapeutics is a discipline focused on bridging experimental and computational technologies and discoveries in the research laboratory to their application in clinical practice. Examples of research components include activities in molecular and cellular biology, pathophysiology, systems biology, bioinformatics, modeling and simulation, and other quantitative sciences to connect basic biological concepts and entities to directly address unmet medical needs. The goals are to use clinical observation as the basis for hypothesis generation to further basic research and to efficiently advance the product of basic research to patients." Translational Medicine and Therapeutics awards will advance training and support career development of scientists engaged in research that significantly integrates cutting-edge technologies with advanced biological, chemical, and pharmacological sciences and engineering methodologies in such areas as (but not restricted to): * Genetics (Molecular, Pharmaco-, Population, Medical) * Genomics (Functional, Structural, Toxico-, Pharmaco-, Comparative) * Systems (Biology and Pharmacology) * Pathways and networks * Integrative biology * Modeling and simulation * Target Identification and Validation * Biomarker Discovery and Validation * Vaccine Development * Molecular Epidimiology * Imaging * Disease Modeling

The National Science Foundation (NSF) Directorates for Engineering (ENG) and Geosciences (GEO), the Divisions of Integrative Organismal Systems (IOS) and Environmental Biology (DEB), in the Directorate for Biological Sciences (BIO), the Division of Computer and Network Systems in the Directorate Computer and Information Science and Engineering (CISE/CNS), and the Division of Chemistry (CHE) in the Directorate for Mathematical and Physical Sciences, in collaboration with the US Department of Agriculture National Institute of Food and Agriculture (USDA NIFA) encourage convergent research that transforms existing capabilities in understanding dynamic soil processes, including soil formation, through advances in sensor systems and modeling. The Signals in the Soil (SitS) program fosters collaboration among the two partner agencies and the researchers they support by combining resources and funding for the most innovative and high-impact projects that address their respective missions. To make transformative advances in our understanding of soils, multiple disciplines must converge to produce environmentally-benign novel sensing systems with multiple modalities that can adapt to different environments and collect and transmit data for a wide range of biological, chemical, and physical parameters. Effective integration of sensor data will be key for achieving a better understanding of signaling interactions among plants, animals, microbes, the soil matrix, and aqueous and gaseous components. New sensor networks have the potential to inform models in novel ways, to radically change how data is obtained from various natural and managed (both urban and rural) ecosystems, and to better inform the communities that directly rely on soils for sustenance and livelihood.

NIST is soliciting applications from eligible institutions of higher education in the U.S. and its territories that offer two- or four- year degrees in academic science, technology, engineering and mathematics (STEM) disciplines, which include but are not limited to biochemistry, biological sciences, chemistry, computer science, engineering, electronics, materials science, mathematics, nanoscale science, neutron science, physical sciences, physics, and statistics, to establish and manage a program to support collaborative research relationships among NIST staff, undergraduate and graduate students, individuals with bachelor's or master's degrees, post-doctoral fellows, and academic affiliates, and the PREP researchers' academic institutions. These collaborative relationships will include research opportunities at the relevant NIST campuses in Boulder, Colorado (CO) (PREP Boulder), or Gaithersburg, Maryland (MD), and/or Charleston, South Carolina (SC) (PREP Gaithersburg). Eligible applicants may apply to establish and manage a PREP Boulder program or a PREP Gaithersburg program or may apply to establish and manage programs for both.

The National Science Foundation (NSF) invites investigators at U.S. organizations to submit proposals to conduct research about the Arctic. Arctic research includes field and modeling studies, data analysis, and synthesis about the arctic region.The goal of the NSF Section for Arctic Sciences, Division of Polar Programs (PLR),??is to gain a better understanding of the Arctic's physical, biological, geological, chemical, social and cultural processes; the interactions of oceanic, terrestrial, atmospheric, biological, social, cultural, and economic systems; and the connections that define the Arctic. The Arctic Sciences and other NSF programs support projects that contribute to the development of the next generation of researchers and scientific literacy for all ages through education, outreach, and broadening participation in science, technology, engineering, and mathematics. Program representatives from polar and other non-polar NSF programs that support arctic research coordinate across NSF, including joint review and funding of arctic proposals and mutual support of special projects with high logistical costs.

The National Science Foundation (NSF) Directorates for Engineering (ENG) and Geosciences (GEO), the Divisions of Integrative Organismal Systems (IOS) and Environmental Biology (DEB), in the Directorate for Biological Sciences (BIO), the Division of Computer and Network Systems in the Directorate Computer and Information Science and Engineering (CISE/CNS), and the Division of Chemistry (CHE) in the Directorate for Mathematical and Physical Sciences, in collaboration with the US Department of Agriculture National Institute of Food and Agriculture (USDA NIFA) encourage convergent research that transforms existing capabilities in understanding dynamic soil processes, including soil formation, through advances in sensor systems and modeling. The Signals in the Soil (SitS) program fosters collaboration among the two partner agencies and the researchers they support by combining resources and funding for the most innovative and high-impact projects that address their respective missions. To make transformative advances in our understanding of soils, multiple disciplines must converge to produce environmentally-benign novel sensing systems with multiple modalities that can adapt to different environments and collect and transmit data for a wide range of biological, chemical, and physical parameters. Effective integration of sensor data will be key for achieving a better understanding of signaling interactions among plants, animals, microbes, the soil matrix, and aqueous and gaseous components. New sensor networks have the potential to inform models in novel ways, to radically change how data is obtained from various natural and managed (both urban and rural) ecosystems, and to better inform the communities that directly rely on soils for sustenance and livelihood.

The goal of the NSF Section for Arctic Sciences, Division of Polar Programs (PLR), is to gain a better understanding of the Arctic's physical, biological, geological, chemical, social and cultural processes; the interactions of oceanic, terrestrial, atmospheric, biological, social, cultural, and economic systems; and the connections that define the Arctic. The Arctic Sciences and other NSF programs support projects that contribute to the development of the next generation of researchers and scientific literacy for all ages through education, outreach, and broadening participation in science, technology, engineering, and mathematics. Program representatives from polar and other non-polar NSF programs that support arctic research coordinate across NSF, including joint review and funding of arctic proposals and mutual support of special projects with high logistical costs.

The DOE SC program in Biological and Environmental Research (BER) hereby announces its interest in receiving applications for research in Environmental Systems Science (ESS), including Terrestrial Ecosystem Science (TES) and Subsurface Biogeochemical Research (SBR). The goal of the Environmental System Science (ESS) activity in BER is to advance a robust, predictive understanding of the set of interdependent physical, biogeochemical, ecological, hydrological, and geomorphological processes for use in Earth system, ecosystem and reactive transport models. Using an iterative approach to model-driven experimentation and observation, and interdisciplinary teams, ESS-supported scientists work to unravel the coupled physical, chemical and biological processes that control the structure and functioning of terrestrial ecosystems and integrated watersheds across critical spatial and temporal scales. This FOA will consider applications that focus on improving the understanding and representation of terrestrial and subsurface environments in ways that advance the sophistication and capabilities of local, regional, and larger scale models.

The Society of Biological Psychiatry offers an annual award of $2,000 each in basic science and in clinical science for the purpose of stimulating international research in biological psychiatry by young investigators.

The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative research proposals in the areas of physical sciences, engineering, materials, mathematics, biology, computing, informatics, social science, and manufacturing of interest to DARPA's Defense Sciences Office (DSO), Microsystems Technology Office (MTO), and Biological Technologies Office (BTO).

The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative research proposals in the areas of physical sciences, engineering, materials, mathematics, biology, computing, informatics, social science, and manufacturing of interest to DARPA's Defense Sciences Office (DSO), Microsystems Technology Office (MTO), and Biological Technologies Office (BTO).

The Plant Genome Research Program (PGRP) supports genome-scale research in plant genomics that addresses challenging questions of biological importance and of relevance to society. The Program encourages the development of innovative tools, technologies and resources that push the boundaries of research capabilities and permit the community to answer seemingly intractable and pressing questions on a genome-wide scale. Emphasis is placed on the creativity of the approach and the scale and depth of the question being addressed. Data produced by plant genomics should be usable, accessible, integrated across scales and of high impact across biology. Training and career advancement in plant genomics is featured as an essential element of scientific progress. The PGRP continues to focus on plants of economic importance and biological processes and interactions that will have broad impact on the scientific research community and society in general.

The Plant Genome Research Program (PGRP) supports genome-scale research in plant genomics that addresses challenging questions of biological importance and of relevance to society. The Program encourages the development of innovative tools, technologies and resources that push the boundaries of research capabilities and permit the community to answer seemingly intractable and pressing questions on a genome-wide scale. Emphasis is placed on the creativity of the approach and the scale and depth of the question being addressed. Data produced by plant genomics should be usable, accessible, integrated across scales and of high impact across biology. Training and career advancement in plant genomics is featured as an essential element of scientific progress. The PGRP continues to focus on plants of economic importance and biological processes and interactions that will have broad impact on the scientific research community and society in general.

The Chemistry of Life Processes (CLP) Program supports fundamental studies of biomolecules or biological systems at the interface of chemistry and biology. The primary contributions and innovations of the proposed research focus on the chemical aspects of the project. The Program supports studies that investigate how molecular structure, dynamics and interactions, as well as reaction thermodynamics and mechanisms are integrated with the chemistry performed by, or intrinsic to, the biological systems.

The Chemistry of Life Processes (CLP) Program supports fundamental studies of biomolecules or biological systems at the interface of chemistry and biology. The primary contributions and innovations of the proposed research focus on the chemical aspects of the project. The Program supports studies that investigate how molecular structure, dynamics and interactions, as well as reaction thermodynamics and mechanisms are integrated with the chemistry performed by, or intrinsic to, the biological systems.

The Biotechnology and Biochemical Engineering (BBE) program supports fundamental engineering research that advances the understanding of cellular and biomolecular processes in engineering biology and eventually leads to the development of enabling technology for advanced manufacturing and/or applications in support of the biopharmaceutical, biotechnology, and bioenergy industries, or with applications in health or the environment.  A quantitative treatment of biological and engineering problems of biological processes is considered vital to successful research projects in the BBE program.

The Biotechnology and Biochemical Engineering (BBE) program supports fundamental engineering research that advances the understanding of cellular and biomolecular processes in engineering biology and eventually leads to the development of enabling technology for advanced manufacturing and/or applications in support of the biopharmaceutical, biotechnology, and bioenergy industries, or with applications in health or the environment.  A quantitative treatment of biological and engineering problems of biological processes is considered vital to successful research projects in the BBE program. 

The Biomaterials program supports fundamental materials research related to (1) biological materials, (2) biomimetic, bioinspired, and bioenabled materials, (3) synthetic materials intended for applications in contact with biological systems, and (4) the processes through which nature produces biological materials.  Projects are typically interdisciplinary and may encompass scales from the nanoscopic to the bulk.  They may involve characterization, design, preparation, and modification; studies of structure-property relationships and interfacial behavior; and combinations of experiment, theory, and/or simulation.  The emphasis is on novel materials design and development and discovery of new phenomena.

The Biomaterials program supports fundamental materials research related to biological materials, biomimetic, bioinspired, and bio-enabled materials, synthetic materials intended for applications in contact with biological systems, and the processes through which nature produces biological materials