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The purpose of this Funding Opportunity Announcement (FOA) is to encourage cooperative agreement (U54) applications from multi-disciplinary groups of investigators to accelerate the rate of progress in determining the functional, pharmacological, neuronal network and whole animal consequences of genetic variants discovered in individuals with various types of epilepsy and to develop strategies for establishing diagnostic criteria and identifying potential targets for intervention. 

The Nemko Prize in Cellular or Molecular Neuroscience, supported by The Nemko Family, recognizes a young neuroscientist's outstanding PhD thesis advancing understanding of molecular, genetic, or cellular mechanisms underlying brain function, including higher function and cognition.

DLS supports fundamental research that increases our understanding of cognitive, linguistic, social, cultural, and biological processes related to children's and adolescents' development and learning.  Research supported by this program will add to our basic knowledge of how people learn and the underlying developmental processes that support learning, with the objective of leading to better educated children and adolescents who grow up to take productive roles as workers and as citizens. Among the many research topics supported by DLS are: developmental cognitive neuroscience; development of higher-order cognitive processes; transfer of knowledge from one domain or situation to another; use of molecular genetics to study continuities and discontinuities in development; development of peer relations and family interactions; multiple influences on development, including the impact of family, school, community, social institutions, and the media; adolescents' preparation for entry into the workforce; cross-cultural research on development and learning; and the role of cultural influences and demographic characteristics on development. Additional priorities include research that: incorporates multidisciplinary, multi-method, microgenetic, and longitudinal approaches; develops new methods, models, and theories for studying learning and development; and integrates different processes (e.g., learning, memory, emotion), levels of analysis (e.g., behavioral, social, neural), and time scales (e.g. infancy, middle childhood, adolescence).

With the generous support of a grant from the National Institute on Alcohol Abuse and Alcoholism of the National Institutes of Health USA we are pleased to offer stipends in partial support of travel to attend the Fifteenth Annual Meeting of the International Behavioural and Neural Genetics Society (IBANGS).  Travel Stipend Details: A limited number of stipends are available for graduate students, post-doctoral fellows, and junior faculty members who have held faculty rank for less than 5 years.

This Funding Opportunity Announcement (FOA) intends to assemble a group of Comprehensive Centers that will adopt scalable technology platforms and streamlined workflows to generate a comprehensive 3D brain cell reference atlas encompassing molecular, anatomical, and physiological annotations of brain cell types in mouse, and incorporate additional genetic and other advanced cell-specific targeting approaches and tools to facilitate this goal. A central goal of this and the three companion FOAs is to build a brain cell census resource that can be widely used throughout the research community.

This funding opportunity announcement (FOA) supports high impact efforts to make resources available to neuroscience researchers.  Projects should engage in one or more of the following activities: facilitating access to cutting edge reagents or techniques, dissemination of resources to new user groups, or innovative approaches to increase the scale/efficiency of resource production and delivery.  Applications focused primarily on technology or software development are not responsive to this FOA, as the focus is on dissemination or provision of resources.  Use of existing technologies to develop new reagents or genetic lines of significant value to the research community may be appropriate. Projects should address compelling needs of broad communities of neuroscience researchers or should offer unique services that otherwise would be unavailable.

TRANSLATIONAL MEDICINE AND THERAPEUTICS: The goal of the PhRMA Foundation's Translational Medicine and Therapeutics Program is to promote the development and use of experimental and computational methods in an integrative approach towards clinical needs in diagnosis, treatment and prevention. This can involve enhanced understanding of human biological and disease processes but requires a strong translational component. This program will support the concepts of Translational Medicine and Therapeutics as defined by the Foundation: "Translational medicine and therapeutics is a discipline focused on bridging experimental and computational technologies and discoveries in the research laboratory to their application in clinical practice. Examples of research components include activities in molecular and cellular biology, pathophysiology, systems biology, bioinformatics, modeling and simulation, and other quantitative sciences to connect basic biological concepts and entities to directly address unmet medical needs. The goals are to use clinical observation as the basis for hypothesis generation to further basic research and to efficiently advance the product of basic research to patients." Translational Medicine and Therapeutics awards will advance training and support career development of scientists engaged in research that significantly integrates cutting-edge technologies with advanced biological, chemical, and pharmacological sciences and engineering methodologies in such areas as (but not restricted to): * Genetics (Molecular, Pharmaco-, Population, Medical) * Genomics (Functional, Structural, Toxico-, Pharmaco-, Comparative) * Systems (Biology and Pharmacology) * Pathways and networks * Integrative biology * Modeling and simulation * Target Identification and Validation * Biomarker Discovery and Validation * Vaccine Development * Molecular Epidimiology * Imaging * Disease Modeling

The primary objective of this FOA is to stimulate innovative Convergent Neuroscience (CN) approaches to establish causal and/or probabilistic linkages across contiguous levels of analysis (e.g., gene, molecule, cell, circuit, system, behavior) in an explanatory model of psychopathology. In particular, applicants should focus on how specific constituent biological processes at one level of analysis contribute to quantifiable properties at other levels, either directly or as emergent phenomena.  Although not required, it is preferable that applications link at least three levels of analysis and include an emphasis on genetics. The projects under this FOA will develop novel methods, theories, and approaches through a CN team framework, bringing together highly synergistic inter/transdisciplinary teams from neuroscience and "orthogonal" fields (e.g., data/computational science, physics, engineering, mathematics, and environmental sciences). Successful teams will combine, expand upon, or develop conceptual frameworks and theoretical approaches, and build explanatory computational models that connect contiguous levels of analysis. Such frameworks, theories, and computational explanatory models should be validated through experimental approaches to elucidate biological underpinnings of complex behavioral (including cognitive and affective) outcomes in psychopathology. Additionally, a goal of this program is to advance research in CN by creating a shared community framework of resources which may be used by the broader research community to further research, as such, successful team will have robust plan for sharing data and other resources.

The purpose of this Funding Opportunity Announcement (FOA) is to encourage projects to generate fundamental knowledge of affective processes. Basic affective science projects should have key downstream consequences for single (e.g., genetic testing consent) and multiple (e.g., adherence to oral chemotherapy regimen) event decisions and behaviors across the cancer prevention and control continuum. The FOA is expected to encourage scientific disciplines that have not traditionally conducted cancer research such as affective and cognitive neuroscience, decision science, and consumer science to elucidate perplexing and understudied problems in basic affective and decision sciences with promise of having downstream implications for cancer prevention and control science.

This Funding Opportunity Announcement (FOA) is issued by the National Institute of Neurological Disorders and Stroke (NINDS) in conjunction with the NIH Pain Consortium. It solicits R21 grant applications from institutions/organizations to perform innovative research that will elucidate the mechanisms underlying migraine, expand our current knowledge of the role of genetic, physiological, biopsychosocial, and environmental influences in migraine susceptibility and progression, and explore new therapeutic targets and therapies for acute migraine management and longer term prevention.

This Funding Opportunity Announcement (FOA) is issued by the National Institute of Neurological Disorders and Stroke (NINDS) in conjunction with the NIH Pain Consortium. It solicits R01 grant applications from institutions/organizations to perform innovative research that will elucidate the mechanisms underlying migraine, expand our current knowledge of the role of genetic, physiological, biopsychosocial, and environmental influences in migraine susceptibility and progression, and explore new therapeutic targets and therapies for acute migraine management and longer term prevention.

We are interested in proposals that address memory or cognition under normal and pathological conditions. This includes proposals that address mechanisms of memory or cognition at the synaptic, cellular, or behavioral level in animals, including humans.We are particularly interested in proposals that incorporate fundamentally new approaches, as well as those that involve human experimentation. Collaborative and cross-disciplinary applications are encouraged. Projects restricted to the creation of conventional mouse knockouts in candidate disease genes identified by association studies, or to broadly overexpress those genes, are discouraged. In addition, projects to perform genetic interaction screens on disease genes in model organisms (yeast, worm, fly, fish) will not be considered, unless the project includes substantive specific aims that investigate the disease relevance of any new genes so discovered in human or mammalian model systems.

The ADAA Career Development Travel Awards are given to help early career professionals who have a research interest in anxiety disorders and depression, such as basic and clinical neurobiology, psychopharmacology, anxiety comorbidities, clinical psychology, genetics, neuroimaging, epidemiology, comparative effectiveness, multicultural issues, public health, as well as other areas. The awards also familiarize and engage aspiring professionals with the membership and work of the association.

This FOA encourages R01 applications from institutions/organizations that propose to study the neurobiological and behavioral mechanisms that might explain how alcohol and stimulants interact at genetic, epigenetic, cellular, neurocircuitry and behavioral levels to promote co-addiction.

This FOA encourages R01 applications from institutions/organizations that propose to study the neurobiological and behavioral mechanisms that might explain how alcohol and stimulants interact at genetic, epigenetic, cellular, neurocircuitry and behavioral levels to promote co-addiction.

The mission of the Biomedical Engineering (BME) program is to provide opportunities to develop novel ideas into discovery-level and transformative projects that integrate engineering and life science principles in solving biomedical problems that serve humanity in the long-term.  The Biomedical Engineering (BME) program supports fundamental research in the following BME themes: Neural engineering (brain science, computational neuroscience, brain-computer interface, neurotech, cognitive engineering) Cellular biomechanics (motion, deformation, and forces in biological systems; how mechanical forces alter cell growth, differentiation, movement, signal transduction, transport, cell adhesion, cell cytoskeleton dynamics, cell-cell and cell-ECM interactions; genetically engineered stem cell differentiation with long-term impact in tissue repair and regenerative medicine) The BME projects must be at the interface of engineering and life sciences, and advance both engineering and life sciences.  The projects should focus on high impact transforming methods and technologies. The project should include methods, models and tools of understanding and controlling of living systems; fundamental improvements in deriving information from cells, tissues, organs, and organ systems; new approaches to the design of structures and materials for eventual medical use in the long-term; and new novel methods of reducing health care costs through new technologies.

Studies funded by our Basic Research RFP will fall into one the following key areas, which are listed in random order: 1. Studies focused on the molecular and biochemical mechanisms regulating SMN expression or mediating SMN function. Results should lead to a better understanding of the requirements for SMN protein biologically, informing therapy development. Such studies may also identify genetic modifiers, upstream regulators of SMN expression / splicing / function, and downstream effectors of SMN functional activity, resulting in novel drug targets.      2.  Studies resulting in greater understanding of the pathophysiology of SMA, using well-validated animal or cellular models of the SMA. This includes focus on the tissue requirements for SMN protein, clarifying the cellular autonomy of the disease in motor neurons and other cells, peripheral versus central manifestations of the disease, and other areas.  3. Early proof-of concept assessment of novel therapeutic approaches for SMA in well-validated animal or cellular models of the disease. 4. Work focused on generating research and clinical trial tools, such as new animal models for SMA, phenotypic cellular assays for SMA, biomarkers or outcome measures for SMA clinical trials, newborn screening protocols, and others.

This Funding Opportunity Announcement (FOA) aims to stimulate the broader research community to utilize a resource funded through the American Recovery and Reinvestment Act of 2009 (Recovery Act) to generate and evaluate hypotheses about the complex interrelationships and multi-directional influences among genetics, brain maturation, neurocognitive function, and psychiatric symptoms during development. This FOA is a strategic effort to disseminate this data resource, stimulate the broader research community to use the resource, and accelerate research on neurodevelopment and trajectories of risk for mental illness. Secondary goals of this initiative are to foster collaborations among researchers from diverse fields of expertise, enhance diversity of research questions and analytic approaches, advance methods for integration across data modalities and levels of analyses (i.e., imaging, genomics, behavior), and encourage inclusion of early stage investigators among these collaborations.

This funding opportunity announcement (FOA) supports high impact efforts to make resources available to neuroscience researchers.  Projects should engage in one or more of the following activities: propagation of cutting edge reagents or techniques, dissemination of resources to new user groups, or innovative approaches to increase the scale/efficiency of resource production and delivery.  Applications focused on technology or software development are not responsive to this FOA, as the focus is on dissemination or provision of resources.  Use of existing technologies to develop new reagents or genetic lines of clear value may be appropriate. Projects should address compelling needs of broad communities of neuroscience researchers or should offer unique services that otherwise would be unavailable.  Projects must support the NINDS mission

The Summer Undergraduate Research Fellowship (SURF) Program at Cincinnati Children's Hospital Medical Center offers undergraduates the chance to explore clinical and basic science research in laboratories in the Department of Pediatrics, University of Cincinnati College of Medicine. The primary goal is to provide students with a foundation for making career choices in the biomedical sciences. Students have the opportunity to work with one of more than 700 faculty members at Cincinnati Children's Hospital Medical Center, many of whom have active research programs that cover all areas of pediatric medicine, including the study of developmental biology, congenital disorders, genetic diseases, cancer, cardiology, neurology and immunology.