Katri Räikkönen, Anu-Katriina Pesonen, Kati Heinonen, Jari Lahti, Niina Komsi, Johan G. Eriksson, Jonathan R. Seckl, Anna-Liisa Järvenpää, and Timo E. Strandberg
Maternal Licorice Consumption and Detrimental Cognitive and Psychiatric Outcomes in Children
American Journal of Epidemiology Advance Access published on October 4, 2009.
doi:10.1093/aje/kwp272
Data are compatible with adverse fetal "programming" by overexposure to glucocorticoids and caution against excessive intake of licorice-containing foodstuffs during pregnancy.
Ursolic acid is a pentacyclic triterpene acid, used in cosmetics,[2] that is also capable of inhibiting various types of cancer cells by inhibiting the STAT3 activation pathway[3][4] and human fibrosarcoma cells by reducing the expression of matrix metalloproteinase-9 by acting through the glucocorticoid receptor.
Ursolic acid is present in many plants, including apples, basil, bilberries, cranberries, elder flower, peppermint, rosemary, lavender, oregano, thyme, hawthorn, prunes. Apple peels contain high quantity of ursolic acid and related compounds which are responsible for the anti-cancer activity of apple. Ursolic acid can also serve as a starting material for synthesis of more potent bioactive derivatives, such as anti-tumor agents
Maurer M, Riesen W, Muser J, Hulter HN, Krapf R.
Neutralization of Western diet inhibits bone resorption independently of K intake and reduces cortisol secretion in humans.
Am J Physiol Renal Physiol. 2003 Jan;284(1):F32-40. Epub 2002 Sep 24.
PMID: 12