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Rudy Garns

Young neurons led astray - 0 views

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    "Cdk5 therefore appears to be crucial only for later stages of the maturation of newborn neurons. The authors suggest that the improper connections formed by these cells could interfere with information processing in the hippocampus. However, they did not carry out any behavioural tests to explore the consequences of blocking cdk5 activity. This would be an interesting thing to do next, given the recent discovery that new neurons are needed for new memories. Nevertheless, the new findings could have important implications for the use of stem cells in cell replacement therapies for neurological diseases, as they suggest that cells would have to be transplanted accurately into specific locations in order to be effective. " (Neurophilosophy)
Rudy Garns

Trust your gut: Too much thinking leads to bad choices - 0 views

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    Don't think too much before purchasing that new car or television. According to a new study in the Journal of Consumer Research, people who deliberate about decisions make less accurate judgments than people who trust their instincts.
Seth Greenblatt

Imagination Engines Inc. - 0 views

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    A radically new form of neural network based artificial intelligence has been conceived that in contrast to preceding forms of AI, builds itself and then enters into an intellectual bootstrapping process wherein it learns from its own mistakes and successes to create useful ideas and strategies. Not only is this technology capable of autonomously inventing and discovering new products, services, and procedures, as it has for numerous international corporations and government agencies, it has also devised several revolutionary neural network paradigms. For these reasons and more, AI visionaries and futurists, such as Dennis Bushnell, NASA Langley's chief scientist and visionary, have called this technology, known as the "Creativity Machine," AI's best bet at creating human to trans-human level intelligence in machines. This technology, based upon an extremely profound scientific discovery, is produced and delivered exclusively by Imagination Engines, Incorporated as either customer tailored or mass produced products.
Rudy Garns

Human facial expressions aren't universal - 0 views

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    Facial expressions, Charles Darwin argued in The Expression of the Emotions in Man and Animals, are a universal window into emotion. But new research challenges that notion, showing that east Asian people struggle to recognise facial expressions that western Caucasians attribute to fear and disgust. By focusing on eyes and brows, Asians miss subtle cues conveyed via the mouth. (13 August 2009 - New Scientist)
Rudy Garns

Neuroscience: Small, furry … and smart - 0 views

  • Much of the work involves making an adult brain behave more like a younger, more flexible version of itself by increasing the organ's plasticity.
  • neuroscientists using genetic engineering to generate cognitively enhanced animals in a bid to understand memory and learning.
  • Tsien created Doogie by overexpressing a subunit of the NMDA receptor called NR2B. This kept the receptors open for longer, strengthening the synaptic link and making it easier for disparate events to be linked together.
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    Tsien, based at Princeton University in New Jersey at the time, named his creation Doogie after the teenage genius in the television programme Doogie Howser, MD. The work was one of the earliest examples of neuroscientists using genetic engineering to generate cognitively enhanced animals in a bid to understand memory and learning.
Rudy Garns

The Legal Brain: How Does the Brain Make Judgments about Crimes? - 0 views

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    In our legal system, judges and juries have to assign responsibility for crimes and decide on appropriate punishments. A new imaging study reveals which area of the brain plays a key role in these cognitive processes. (Scientific American)
Rudy Garns

More Evidence That Intelligence Is Largely Inherited: Researchers Find That Genes Deter... - 0 views

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    In a study published recently in the Journal of Neuroscience, UCLA neurology professor Paul Thompson and colleagues used a new type of brain-imaging scanner to show that intelligence is strongly influenced by the quality of the brain's axons, or wiring that sends signals throughout the brain. The faster the signaling, the faster the brain processes information. And since the integrity of the brain's wiring is influenced by genes, the genes we inherit play a far greater role in intelligence than was previously thought.
Rudy Garns

Neuroscientists Map Intelligence In The Brain - 0 views

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    Neuroscientists at the California Institute of Technology (Caltech) have conducted the most comprehensive brain mapping to date of the cognitive abilities measured by the Wechsler Adult Intelligence Scale (WAIS), the most widely used intelligence test in the world. The results offer new insight into how the various factors that comprise an "intelligence quotient" (IQ) score depend on particular regions of the brain.
Rudy Garns

Multitasking May Not Mean Higher Productivity : NPR - 0 views

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    A new study says so-called "heavy multitaskers" have trouble tuning out distractions and switching tasks compared with those who multitask less. And there's evidence that multitasking may weaken cognitive ability. Stanford University professor Clifford Nass explains the work.
Rudy Garns

Researchers Identify Critical Gene For Brain Development, Mental Retardation - 0 views

  • brain protein srGAP2 can also impose cell shape by directly bending membranes, forming filopodia as a mean to control the migration and branching of neurons during brain development
  • establishing the neural wiring necessary to function normally depends on the ability of neurons to make finger-like projections of their membrane called filopodia.
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    In laying down the neural circuitry of the developing brain, billions of neurons must first migrate to their correct destinations and then form complex synaptic connections with their new neighbors.
emedevents

Flu Vaccine Expected to Protect Against Most U.S. H3N2 Viruses | eMedEvents - 0 views

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    A novel bioinformatics approach can predict vaccine effectiveness for the influenza season, and indicates that the current vaccines are likely to be effective against H3N2 flu viruses in the U.S. 2017/2018 flu season, according to research published online Nov. 29 in F1000 Research. Slobodan Paessler, D.V.M., Ph.D., from the University of Texas Medical Branch, and Veljko Veljkovic, Ph.D., from Biomed Protection, both in Galveston, Texas, used a bioinformatics platform to predict vaccine effectiveness for the 2017/2018 influenza season in the United States. The hemagglutinin HA1 region of 251 and 113 human H3N2 viruses collected in Australia and the United States from July to September 2017 were analyzed. The informational spectrum method-based phylogenetic analysis of H3N2 viruses was performed to serve as a base for predicting vaccine effectiveness. The researchers found that analyses of Australian viruses generated two clusters; the vaccine virus was placed in the smaller group. As a result, the vaccine was predicted not to be efficient against most Australian H3N2 viruses in the 2017 flu season; low vaccine effectiveness was reported in Australia in the 2017 flu season in accordance with this prediction. The U.S. H3N2 viruses were also grouped into two clusters, but the vaccine virus was placed in the largest cluster encompassing 71 percent of analyzed viruses. Consequently, the vaccine effectiveness is expected not to be suboptimal in the United States.
Rudy Garns

An underlying cause for psychopathic behavior? - 2 views

  • impairment in the emotional aspects of these abilities may account for psychopathic behaviour.
  • ToM is made up of different aspects: a cognitive part, which requires inferences about knowledge and beliefs, and another part which requires the understanding of emotions.
  • striking similarities between the mental impairments observed in psychopaths and those seen in patients with frontal lobe damage.
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  • The pattern of impairments in the psychopathic participants showed a remarkable resemblance to those in the participants with frontal lobe damage, suggesting that an underlying cause of the behavioural disturbances observed in psychopathy may be dysfunction in the frontal lobes.
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    Psychopaths are known to be characterized by callousness, diminished capacity for remorse, and lack of empathy. However, the exact cause of these personality traits is an area of scientific debate. The results of a new study, reported in the May 2010 issue of Elsevier's Cortex, show striking similarities between the mental impairments observed in psychopaths and those seen in patients with frontal lobe damage.
Rudy Garns

Of Mice and Models - 0 views

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    "Now a recent breakthrough by the Cambridge neuroscientist and geneticist Seth Grant may provide a third possibility. In a report published in the June 2008 issue of Nature Neuroscience, Grant and his colleagues analyzed synapses in organisms of increasing evolutionary complexity, from single-celled organisms to vertebrates. They found that more advanced organisms also had more complex synapses, allowing neurons to communicate in more complicated ways." Seed
Rudy Garns

Politika Erotika: DAVID BROOKS: The Morality Line - 0 views

  • There still seems to be such things as selves, which are capable of making decisions and controlling destiny. It’s just that these selves can’t be seen on a brain-mapping diagram, and we no longer have any agreement about what they are.
  • we are renegotiating what you might call the Morality Line, the spot where background forces stop and individual choice — and individual responsibility — begins. The killings happen at a moment when the people who explain behavior by talking about biology, chemistry and social science are assertive and on the march, while the people who explain behavior by talking about individual character are confused and losing ground.
  • now the language of morality is often replaced with the language of determinism. >
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  • It’s important knowledge, but it’s had the effect of reducing the scope of the human self. “Man is the measure of all things,” the Greek philosopher Protagoras declared millenniums ago. But in the realm of the new science, the individual is like a cork bobbing on the currents of giant forces: evolution, brain chemistry, stress and upbringing. Human consciousness is merely an epiphenomena of the deep and controlling mental processes that lie within.
Rudy Garns

Scientist Finds the Beginnings of Morality in Primate Behavior - New York Times - 0 views

  • Marc Hauser, an evolutionary biologist at Harvard, proposed in his book “Moral Minds” that the brain has a genetically shaped mechanism for acquiring moral rules, a universal moral grammar similar to the neural machinery for learning language.
  • Frans de Waal defends against philosopher critics his view that the roots of morality can be seen in the social behavior of monkeys and apes.
  • human morality would be impossible without certain emotional building blocks that are clearly at work in chimp and monkey societies
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  • other chimpanzees would console the loser.
  • Social living requires empathy
  • reconciliation
  • human morality may be severely limited by having evolved as a way of banding together against adversaries, with moral restraints being observed only toward the in group, not toward outsiders.
  • eciprocity and fairness
  • Chimps are more likely to share food with those who have groomed them.
  • These four kinds of behavior — empathy, the ability to learn and follow social rules, reciprocity and peacemaking — are the basis of sociality.
  • People enforce their society’s moral codes much more rigorously with rewards, punishments and reputation building. They also apply a degree of judgment and reason, for which there are no parallels in animals.
  • Capuchin monkeys show their displeasure if given a smaller reward than a partner receives for performing the same task
  • reason is generally brought to bear only after a moral decision has been reached
  • Morality, he writes, is “a sense of right and wrong that is born out of groupwide systems of conflict management based on shared values.” The building blocks of morality are not nice or good behaviors but rather mental and social capacities for constructing societies “in which shared values constrain individual behavior through a system of approval and disapproval.”
  • Some animals are surprisingly sensitive to the plight of others.
Rudy Garns

Study Finds Brain Injury Changes Moral Judgment - New York Times - 0 views

  • native revulsion
  • ventromedial prefrontal cortex
  • active during moral decision-making
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  • a very specific kind of emotion-based judgment is altered when the region is offline
  • emotional system
  • utilitarian cost-benefit analyses
  • ventromedial area
  • ventromedial area
  • blind to subtle social cues, making them socially awkward
  • strongly rejected doing harm to others in situations that were not a matter of trading one certain death for another.
  • direct action to kill or harm someone
  • Those with ventromedial injuries were about twice as likely as the other participants to say they would push someone in front of the train
  • navigate social interactions
  • brain stem
  • amygdala
  • emotional memories,
  • social emotions that we can feel, like embarrassment, guilt, compassion that are critical to guiding our social behavior,
  • ension between cost-benefit calculations and instinctive emotion
  • ancient principle: respect for the life of another human being
    • Rudy Garns
       
      It would be interesting to see whether other primates use the ventromedial cortex for similar responses to dilemmas involving conspecifics.
  • increased willingness to kill or harm another person if doing so would save others' lives
    • Rudy Garns
       
      I wonder what would happen if you adjust the identity of the sacrificable person. What happens if person is a stranger versus a family member? They do run the "smother your baby" dilemma. Does it make a difference if it is a stranger? What about alternative to the other five victims? What information is the VMPFC working with?
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