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emedevents

Flu Vaccine Expected to Protect Against Most U.S. H3N2 Viruses | eMedEvents - 0 views

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    A novel bioinformatics approach can predict vaccine effectiveness for the influenza season, and indicates that the current vaccines are likely to be effective against H3N2 flu viruses in the U.S. 2017/2018 flu season, according to research published online Nov. 29 in F1000 Research. Slobodan Paessler, D.V.M., Ph.D., from the University of Texas Medical Branch, and Veljko Veljkovic, Ph.D., from Biomed Protection, both in Galveston, Texas, used a bioinformatics platform to predict vaccine effectiveness for the 2017/2018 influenza season in the United States. The hemagglutinin HA1 region of 251 and 113 human H3N2 viruses collected in Australia and the United States from July to September 2017 were analyzed. The informational spectrum method-based phylogenetic analysis of H3N2 viruses was performed to serve as a base for predicting vaccine effectiveness. The researchers found that analyses of Australian viruses generated two clusters; the vaccine virus was placed in the smaller group. As a result, the vaccine was predicted not to be efficient against most Australian H3N2 viruses in the 2017 flu season; low vaccine effectiveness was reported in Australia in the 2017 flu season in accordance with this prediction. The U.S. H3N2 viruses were also grouped into two clusters, but the vaccine virus was placed in the largest cluster encompassing 71 percent of analyzed viruses. Consequently, the vaccine effectiveness is expected not to be suboptimal in the United States.
Rudy Garns

Disgust as Embodied Moral Judgment - 0 views

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    How, and for whom, does disgust influence moral judgment? In 4 experiments participants made moral judgments while experiencing extraneous feelings of disgust. Disgust was induced in Experiment 1 by exposure to a bad smell, in Experiment 2 by working in a disgusting room, in Experiment 3 by recalling a physically disgusting experience, and in Experiment 4 through a video induction. In each case, the results showed that disgust can increase the severity of moral judgments relative to controls. Experiment 4 found that disgust had a different effect on moral judgment than did sadness. In addition, Experiments 2-4 showed that the role of disgust in severity of moral judgments depends on participants' sensitivity to their own bodily sensations. Taken together, these data indicate the importance - and specificity - of gut feelings in moral judgments.
Rudy Garns

An underlying cause for psychopathic behavior? - 2 views

  • impairment in the emotional aspects of these abilities may account for psychopathic behaviour.
  • ToM is made up of different aspects: a cognitive part, which requires inferences about knowledge and beliefs, and another part which requires the understanding of emotions.
  • striking similarities between the mental impairments observed in psychopaths and those seen in patients with frontal lobe damage.
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  • The pattern of impairments in the psychopathic participants showed a remarkable resemblance to those in the participants with frontal lobe damage, suggesting that an underlying cause of the behavioural disturbances observed in psychopathy may be dysfunction in the frontal lobes.
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    Psychopaths are known to be characterized by callousness, diminished capacity for remorse, and lack of empathy. However, the exact cause of these personality traits is an area of scientific debate. The results of a new study, reported in the May 2010 issue of Elsevier's Cortex, show striking similarities between the mental impairments observed in psychopaths and those seen in patients with frontal lobe damage.
emedevents

AEI - Dental Continuing Medical Education | Continuing Education in Cayman Islands, Geo... - 0 views

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    American Educational Institute (AEI) Medical-Dental-Legal Update is organized by American Educational Institute (AEI) and will be held during Oct 02, 2017 - Apr 27, 2018 at Ritz-Carlton Grand Cayman, George Town, Grand Cayman, Cayman Islands. The target audience for this medical event is Dentists. This CME Conference has been approved for a maximum of 20 AMA PRA Category 1 Credits. Conference Description : You practice in a dynamic and challenging environment. While keeping clinically current is imperative, it isn't enough. You must also acquire the skills necessary to navigate a professional liability minefield, manage a more effective and efficient practice, and navigate a maze of healthcare laws and regulations. The 2017-18 Medical-Dental-Legal Update Update is designed to assist you in that endeavor. The course, offered weekly in 32 enviable destinations, is a unique, 20-hour survey of the intersection of medicine and law as well as selected clinical topics. Produced in state-of-the-art production studios with broadcast-grade, HD digital technology. This Conference offers vital instruction from national experts in the fields of law, medicine, dentistry, asset protection, revenue cycle management and practice management. And their presentations include discussions ranging from domestic violence, payment receipt optimization, medical malpractice, fraud and abuse, and optimizing retirement and benefit plan structures, to the oral-systemic connection, medical errors, Hepatitis B & C, neurology and cardiovascular fitness.
Rudy Garns

Of Mice and Models - 0 views

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    "Now a recent breakthrough by the Cambridge neuroscientist and geneticist Seth Grant may provide a third possibility. In a report published in the June 2008 issue of Nature Neuroscience, Grant and his colleagues analyzed synapses in organisms of increasing evolutionary complexity, from single-celled organisms to vertebrates. They found that more advanced organisms also had more complex synapses, allowing neurons to communicate in more complicated ways." Seed
Rudy Garns

Disgust, Morality, and Human Identity - 0 views

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    Our understanding of disgust and morality is in its infancy, yet technological advances in neurobiology, an increasing willingness to engage in interdisciplinary dialogue, to take religion seriously as a dimension of human nature and experience, and growing knowledge of cultural differences, have created a climate within which a breakthrough in our understanding of morality could soon occur. (Heather Looy :: Global Spiral)
Rudy Garns

Mixing Memory : Emotion, Reason, and Moral Judgment - 0 views

  • emotion and intuition, both of which operate automatically and unconsciously for the most part, play a much larger role than most philosophers and psychologists had previously been willing to admit.
  • VMPC plays a role in encoding the reward value of stimuli, as well as emotions like fear.
  • determines approach and avoidance behavior.
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  • patients with damage to the VMPC, who have trouble processing emotional value as a result of that damage, would behave differently in those scenarios than normal individuals (and other brain-damaged patients
  • The standard interpretation of these results is that in the impersonal scenarios, people are making the moral decision using conscious reasoning. Specifically, they are thought to be using utilitarian ethical principles to make the decision to flip the switch and kill one person to save five. In the personal scenarios, however, people tend not to make utilitarian decisions, and researchers therefore believe that they are basing their decision on the emotional response the situation elicits.
  • damage to the VMPC can make decisions related to the value of a stimulus more difficult
  • there was a difference between the normal patients (and brain-damaged elsewhere patients) and the VMPC-damaged patients for the high-conflict personal moral scenarios. The normal and non-VMPC brain-damaged patients said "no" (they wouldn't smother the baby, e.g.) about 80% of the time in response to these scenarios, while the VMPC-damaged patients said no less than 60% of the time (in fact, their response rate was pretty close to 50-50).
  • more rational
  • they just didn't know how to respond to those scenarios
  • unable to decide
  • when people are making these decisions, both the emotional reaction and the moral principle are available at the same time, and one will win out over the other, depending largely on the strength of the emotional response (which is strong in the personal scenarios, and weak in the impersonal ones, at least when they're just being read on paper). This would be inconsistent with strong intuitionist theories of moral judgment.
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    Koenigs, M., Young, L., Adolphs, R., Tranel, D., Cushman, F., Hauser, M., & Damasion, A. (2007). Damage to the prefrontal cortex increases utilitarian moral judgements. Nature.
Rudy Garns

Anterior cingulate cortex - Wikipedia - 0 views

  • the dorsal anterior cingulate cortex is primarily related to rational cognition while the ventral is more related to emotional cognition.
  • early learning and problem solving
  • processing top-down and bottom-up stimuli and assigning appropriate control to other areas in the brain.
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  • ACC response in Stroop task experiments (designed to measure adherence to sequential decision-making paths) remains relatively elevated in typical human subjects, as the alternative - spontaneity - is sacrificed.
  • A typical task that activates the ACC involves eliciting some form of conflict within the participant that can potentially result in an error.
  • inability to detect errors, severe difficulty with resolving stimulus conflict in a Stroop task, emotional instability, inattention, and akinetic mutism
  • difficulty in dealing with conflicting spatial locations in a Stroop-like task and having abnormal ERNs
  • appears to play a role in a wide variety of autonomic functions, such as regulating blood pressure and heart rate, as well as rational cognitive functions, such as reward anticipation, decision-making, empathy and emotion.
Rudy Garns

Scientist Finds the Beginnings of Morality in Primate Behavior - New York Times - 0 views

  • Marc Hauser, an evolutionary biologist at Harvard, proposed in his book “Moral Minds” that the brain has a genetically shaped mechanism for acquiring moral rules, a universal moral grammar similar to the neural machinery for learning language.
  • Frans de Waal defends against philosopher critics his view that the roots of morality can be seen in the social behavior of monkeys and apes.
  • human morality would be impossible without certain emotional building blocks that are clearly at work in chimp and monkey societies
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  • other chimpanzees would console the loser.
  • Social living requires empathy
  • reconciliation
  • human morality may be severely limited by having evolved as a way of banding together against adversaries, with moral restraints being observed only toward the in group, not toward outsiders.
  • eciprocity and fairness
  • Chimps are more likely to share food with those who have groomed them.
  • These four kinds of behavior — empathy, the ability to learn and follow social rules, reciprocity and peacemaking — are the basis of sociality.
  • People enforce their society’s moral codes much more rigorously with rewards, punishments and reputation building. They also apply a degree of judgment and reason, for which there are no parallels in animals.
  • Capuchin monkeys show their displeasure if given a smaller reward than a partner receives for performing the same task
  • reason is generally brought to bear only after a moral decision has been reached
  • Morality, he writes, is “a sense of right and wrong that is born out of groupwide systems of conflict management based on shared values.” The building blocks of morality are not nice or good behaviors but rather mental and social capacities for constructing societies “in which shared values constrain individual behavior through a system of approval and disapproval.”
  • Some animals are surprisingly sensitive to the plight of others.
Rudy Garns

Neuroscience: Small, furry … and smart - 0 views

  • Much of the work involves making an adult brain behave more like a younger, more flexible version of itself by increasing the organ's plasticity.
  • neuroscientists using genetic engineering to generate cognitively enhanced animals in a bid to understand memory and learning.
  • Tsien created Doogie by overexpressing a subunit of the NMDA receptor called NR2B. This kept the receptors open for longer, strengthening the synaptic link and making it easier for disparate events to be linked together.
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    Tsien, based at Princeton University in New Jersey at the time, named his creation Doogie after the teenage genius in the television programme Doogie Howser, MD. The work was one of the earliest examples of neuroscientists using genetic engineering to generate cognitively enhanced animals in a bid to understand memory and learning.
Rudy Garns

Neuroscience and Decision Making - 0 views

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    The purpose of this paper is to provide an integrative review of the area of Neuroscience and its relationship to Behavioral Decision Making. I will start by discussing Prospect theory and the role that neuroscience can play in understanding human behavior under risky situations. I will then discuss the Somatic Marker Hypothesis and its application in decision making. Further, I will highlight some techniques that are used to measure neural responses. Finally, I will end with future avenues of research where Neuroscience techniques can be applied in studying different Marketing phenomena.
Rudy Garns

Young neurons led astray - 0 views

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    "Cdk5 therefore appears to be crucial only for later stages of the maturation of newborn neurons. The authors suggest that the improper connections formed by these cells could interfere with information processing in the hippocampus. However, they did not carry out any behavioural tests to explore the consequences of blocking cdk5 activity. This would be an interesting thing to do next, given the recent discovery that new neurons are needed for new memories. Nevertheless, the new findings could have important implications for the use of stem cells in cell replacement therapies for neurological diseases, as they suggest that cells would have to be transplanted accurately into specific locations in order to be effective. " (Neurophilosophy)
Rudy Garns

More Evidence That Intelligence Is Largely Inherited: Researchers Find That Genes Deter... - 0 views

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    In a study published recently in the Journal of Neuroscience, UCLA neurology professor Paul Thompson and colleagues used a new type of brain-imaging scanner to show that intelligence is strongly influenced by the quality of the brain's axons, or wiring that sends signals throughout the brain. The faster the signaling, the faster the brain processes information. And since the integrity of the brain's wiring is influenced by genes, the genes we inherit play a far greater role in intelligence than was previously thought.
Rudy Garns

Losers With Winners' Brains - 0 views

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    One of the mysteries of gambling is that even when we should know we're going to lose, we somehow think we're going to win. Dr. Luke Clark, from the Department of Experimental Psychology at the University of Cambridge, may have discovered one of the reasons why. Using MRI, he studied brain activity in people gambling, looking particularly at "near misses" in which a loss seems close to a win. He found that the brain activated the same reward system that is activated in a real win, despite the fact that people report that these near misses are unpleasant. (CBC Radio | Quirks & Quarks | February 21, 2009)
Rudy Garns

Is there wisdom in disgust? - moral psychology - 0 views

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    Dan Jones writes an interesting essay in a recent issue of Science (PDF here) on how work in evolutionary theory, moral philosophy, and neuroscience casts doubt on the idea that disgust embodies a deep-seated wisdom. Instead it provides an emerging portrait of an evolutionarily constrained emotion that is a poor guide to ethical action. (Deric Bownds' MindBlog)
Rudy Garns

Neural correlates of third party punishment. - 0 views

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    The level of activity in the right dorsolateral prefrontal cortex correlated with the level of responsibility that the volunteers assigned to the defendant, whereas activity in the amygdala, the medial prefrontal cortex and the posterior cingulate cortex predicted punishment magnitude, indicating that distinct neural systems underlie the two processes in legal decision making. (Deric Bownds' MindBlog)
Rudy Garns

Social Decision-Making: Insights from Game Theory and Neuroscience - 0 views

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    By combining the models and tasks of Game Theory with modern psychological and neuroscientific methods, the neuroeconomic approach to the study of social decision-making has the potential to extend our knowledge of brain mechanisms involved in social decisions and to advance theoretical models of how we make decisions in a rich, interactive environment. Research has already begun to illustrate how social exchange can act directly on the brain's reward system, how affective factors play an important role in bargaining and competitive games, and how the ability to assess another's intentions is related to strategic play. These findings provide a fruitful starting point for improved models of social decision-making, informed by the formal mathematical approach of economics and constrained by known neural mechanisms. -- Sanfey 318 (5850): 598 -- Science
Rudy Garns

Is anterior cingulate cortex necessary for cognitive control? -- Fellows and Farah 128 ... - 0 views

  • activated when tasks require the ongoing adjustment of the allocation of attention.
  • All four subjects with dACC damage showed normal adjustments in performance following manipulation of response conflict in both Stroop and go–no go tasks
  • damage to the dACC did not impair the phenomenon of post-error slowing, nor alter the ability to adjust performance in response to explicit speed or accuracy instructions.
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  • cognitive control, as assessed by four different measures in two different tasks, appears to be intact in these subjects, arguing against a necessary role for dACC in this process.
  • cognitive control.
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    Abstract
Rudy Garns

Cognitive science research to revolutionize the legal system - 0 views

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    What if a jury could decide a man's guilt through mind reading? What if reading a defendant's memory could betray their guilt? And what constitutes 'intent' to commit murder? These are just some of the issues debated and reviewed in the inaugural issue of WIREs Cognitive Science, the latest interdisciplinary project from Wiley-Blackwell, which for registered institutions will be free for the first two years. In the article "Neurolaw," in the inaugural issue of WIREs Cognitive Science, co-authors Walter Sinnott-Armstrong and Annabelle Belcher assess the potential for the latest cognitive science research to revolutionize the legal system.
Rudy Garns

Where is my mind? - 0 views

  • Is what my robot does when it ‘decides’ to change course a sort of thing which if it had happened inside the robot, ‘I would have had no hesitation in accepting as part of [a] cognitive process?’
  • But how am I to understand the hypothesis that it would (or wouldn’t) have changed course if it had collided with the couch in my head?
  • His real argument is that, barring a principled reason for distinguishing between what Otto keeps in his notebook and what Inga keeps in her head, there’s a slippery slope from the one to the other.
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  • The mark of the mental is its intensionality (with an ‘s’); that’s to say that mental states have content; they are typically about things.
  • What I should have said isn’t that only what’s literally and unmetaphorically mental has content, but that if something literally and unmetaphorically has content, then either it is mental (part of a mind) or the content is ‘derived’ from something that is mental. ‘Underived’ content (to borrow John Searle’s term) is the mark of the mental; underived content is what minds and only minds have.
  • Externalism needs internalism; but not vice versa. External representation is a side-show; internal representation is ineliminably the main event.
  • your internal model of the world contains stuff that the world itself does not; this happens not just when your beliefs are false but also when they are hypothetical (‘if there are clouds, there will be rain’ can be true even if there aren’t any clouds); or when they are modal (‘it might rain’ can be true even if it doesn’t rain); or when they are in the past or future tense (‘it used to rain here a lot’ can be true even if it doesn’t rain here anymore).
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    There is a gap between the mind and the world, and (as far as anybody knows) you need to posit internal representations if you are to have a hope of getting across it. Mind the gap. You'll regret it if you don't. (Jerry Fodor review of Clark)
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