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Assunta Krehl

Pharmafocus.com - 0 views

  • Canada has always had to fight hard to attract talent and investment
  • MaRS Vital to Toronto's life sciences vision is MaRS (derived from Medical and Related Sciences) a non-profit organisation and business centre located in the heart of the city. Its core function is as a biotech incubator and business park, known as MaRS Discovery District. The venture was first established in 2000 to help foster and accelerate the growth of successful Canadian businesses and, after some uncertain times, it is now gathering momentum. A separate technology transfer office, MaRS Innovation, has also been established that, it is hoped, can be a world beater in its own right (see Turning good ideas into world beaters below). The location of the MaRS building in central Toronto is important, as it is just a stone's throw away from an existing cluster of universities and academic hospitals. MaRS has many links with other research-based organisations, including collaborations with three local universities, 10 academic teaching hospitals and the Ontario Institute for Cancer Research. MaRS occupies the Old Toronto general hospital, where insulin was first discovered by Best and Banting in 1921 and then developed for use in human trials. The 21st Century organisation can build on this heritage in patient-focused discovery and development. Formerly the head of venture capital firm Primaxis, Ilse Treurnicht is chief executive of MaRS Discovery District. She acknowledges the crisis in venture capital funding, and says Canada's sector has always had less access funds through this route than other countries. This is one of the drivers behind the search for a new approach. Treurnicht says the old models of building biotech and life sciences businesses have to be discarded, as they have failed to build companies with critical mass. She says MaRS' new 'Convergence Innovation' strategy of bringing science, capital and business together will pay off.
  • "We call our strategy 'Convergence Innovation' and what we are trying to do is move away from the old linear model of academics struggling in their spare time to build companies or entrepreneurs doing this in a very incremental way."It takes time and it has many risk points along the way. So using this Convergence centre model to create a much more dynamic organisation which can help accelerate good ideas towards the commercialisation." But she says Canada's geography and demographics are always going to be a challenge. "This is a very large country with a small population. If you think in terms of clusters and hub regions, Canada's business hubs are separated geographically, and there is not much in between in terms of people."That means we can't try to be a little United States, because we just won't show up on the radar. We have to take a different approach. We have to think about collaboration as our potential competitive advantage - that means using networks and associations to solve problems and build businesses."So as new opportunities emerge, we can take them to market faster and hopefully with a higher success rate." The centre currently accommodates numerous start up companies, as well as those providing legal and financial services to them. AstraZeneca and GlaxoSmithKline also have offices on site. In all, MaRS provides mentoring for over 200 different companies across Ontario, and runs courses on entrepreneurship and preparing products for market.
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  • Transition Therapeutics is one of the companies based at MaRS, and is an example of a biopharmaceutical company that is taking a new approach to the science and business of drug development.
  • Now Toronto's MaRS Innovation (MI) has been launched to try to guide and accelerate these promising ideas out of the wilderness and onto the market. MI is a not-for-profit technology transfer company that will channel all the best ideas to come out of Toronto's renowned academic centres. In the Toronto and Ontario area there were between 14-16 different technology transfer offices in the different institutions, and MaRS Innovation resolved to bring these interests together into a single entity after industry partners told them it was an inefficient way to do business. Bringing together the different institutions under one umbrella organisation has been an arduous task for MaRS, but the reward could be considerable for all parties. MI now oversees probably the largest intellectual property pipeline of its kind, representing about $1 billion in annual research spending. This means MI will be a unified route for all of Toronto's academics and their institutions when they want to develop and commercialise a bright idea. Most importantly, investors from industry who are looking to collaborate will now be able to deal with just organisation and one IP process. MI will cover patentable ideas across a broad range of areas, and not just life sciences - the discovery pipeline in physical sciences, information and communication technology, and green technology ('cleantech') will all be funnelled through MI. MI now represents three universities, 10 academic teaching hospitals and the Ontario Institute for Cancer Research. MaRS Innovation, with support from MaRS and BioDiscovery Toronto, will advance commercialisation through industry partnerships, licensing and company creation.
  • MI has just announced its first two commercialisation deals with academic partners in the city. The first is with the Samuel Lunenfeld Research Institute of Mount Sinai Hospital to develop stem cell from umbilical cords to treat cardiovascular disease, diabetes and neurological disorders. "With the Toronto area identified as a world-leading cluster in stem cell research, we are extremely excited to have identified this technology as our first commercialisation opportunity," said Dr Hofstein.
  • ts chief executive is Dr Rafi Hofstein. Hofstein has been headhunted from Israel where he was chief executive of Hadasit, the technology transfer company of the Hadassah Medical Organization in Jerusalem and chair of the publicly-traded company Hadasit BioHolding. He brings this considerable experience in technology transfer to what he thinks is a groundbreaking enterprise."MaRS Innovation is a unique global initiative, and I must commend the institutional leaders in Toronto for pulling this innovation powerhouse together to strengthen commercialisation output." He adds: "I believe this is going to modernise the whole notion of tech transfer." He says the scale and diversity of MaRS Innovation's remit puts it into a league of its own. Other research clusters elsewhere in the world have attempted similar projects before, but have been thwarted by the difficulty in bringing parties together. MaRS Innovation will also help launch and grow new spin-off companies and incubate them for 2-3 years to ensure a strong commercial footing. Hofstein says MI will also fund proof of concept trials which will persuade major pharma companies to invest in their development.
  • "Our partnership with MaRS Innovation on developing methods for using stem cells for diseases such as diabetes will allow us to work towards advancing care for these critical conditions."
  • The second collaboration is between MI and The University of Toronto (U of T) and involves a novel sustained release formulation of nitric oxide (NO) for applications in wound healing, including diabetic ulcers. "There are 300 million diabetics worldwide, of which some 15% develop troublesome foot ulcers. This wound healing technology is extremely exciting, making it an early commercialisation opportunity that MaRS Innovation has identified as being a potential win for some 45 million diabetics globally," said Dr Hofstein.
  • "This is one of many new commercialisation ventures that will be initiated by MaRS Innovation, our partner in commercialisation of research with 13 other academic institutions across the Greater Toronto Area," said Paul Young, U of T's vice-president, Research. "We at U of T are delighted that this innovation from Dr Lee will be taken to the marketplace to the benefit of society and the economy of Ontario and Canada." By aggregating the leading edge science of its institutional members and being a one-stop commercialisation centre for industry, entrepreneurs and investors, MI could really help put Toronto and Canada on the map."MaRS Innovation is deeply committed to facilitating strategic research collaborations with industry partners, strengthening the innovation capacity of Canadian industry through adoption of new technologies, and launching a new generation of robust, high-growth Canadian companies that will become global market leaders," added Dr Hofstein. "We look forward to working closely with all of our institutional members and to continue to jointly announce exciting commercial opportunities."
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    Canada has always had to fight hard to attract talent and investment. As stated in Pharmafocus.com, "MaRS Discovery District helps to foster and accelerate the growth of successful Canadian businesses." MaRS Innovation has also been launched to accelerate ideas onto the market.
Assunta Krehl

Local - A green leader in her own right - TheRecord.com - 0 views

  • Studio Earth. The youth workshop hosted by Social Innovation Generation -- a working group at the University of Waterloo -- is designed for young people interested in environmental issues.
  • Cullis-Suzuki said she's looking forward to speaking about social innovation. Innovators are badly needed to build a sustainable economy, she said.
  • The social technology workshop will be on using the internet for social purposes. It will be led by Joseph Dee of the MaRS Centre, a Toronto centre for scientific research, and Sam Ladner, a York University sociologist.
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  • social and environmental change
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    Cullis-Suzuki talks about social innovation and environmental change and will be talk at Studio Earth. Studio Earth Participants will attend on of three workshops. Mention of Social Technology workshop will be using the internet for social purposes which will be led by Joseph Dee.
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    Cullis-Suzuki talks about social innovation and environmental change and will be talk at Studio Earth. Studio Earth Participants will attend on of three workshops. Joseph Dee will lead the Social Technology workshop - using the internet for social purposes. Jan 9, 2009
Assunta Krehl

Media Advisory - Building Ontario's green economy - Canada Newswire - 0 views

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    The Cleantech Growth and Go-To-Market Report - an in-depth analysis of Ontario's cleantech sector along with recommendations for positioning Ontario as a global leader. Event will happen at the MaRS Centre February 17, 2009.
Assunta Krehl

7 Opportunities in the Current Recession - Canadian Entrepreneur - 0 views

  • I attended the Wisdom Exchange today at the Mars Discovery District in Toronto, an annual gathering of leading growth firms sponsored by the Ontario government. Ontario’s ministry of small business recognizes that a tiny minority of SMEs, the export-oriented gazelles, account for a disproportionate share of job creation, and it does a great job of encouraging, motivating and supporting the CEOs of such companies through educational opportunities such as the Wisdom Exchange.
  • Jayson Myers, the respected economist who now heads up Canada's largest industry association, Canadian Manufacturers & Exporters.
  • Myers offered a fair bit of bad news to the group – he warned that the recession “will be deeper and last longer than consensus forecasts,” and that total Canadian merchandise exports have actually been falling for six years.
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  • But here is the good news. Myers also cited a whole listfull of business opportunities created by the current downturn. Not every company is in a position to seize these opportunities, but those who can should definitely be looking at this list as a recipe for action.Opportunities in the Current Recession:· For companies with cash and investment strength· Replace competitors (who falter or struggle in this economy)· Acquisitions· Respond to new and emerging customer demand· New product and market development· Infrastructure and Innovation (including the smart grid, green energy, health care, logistics and security, and energy – all areas where Canadian companies have some advantages)· Product specialization, services, new processes, new skills
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    Wisdom Exchange Event was held at the MaRS Centre Feb 19, 2009. This event gathers leading growh firms and it is sponsored by the Ontario Government. Jason Myers, head of Canadian Manufacteurers & Exporters mentions the Canadian economy will get worse and last longer but there will be a list of business opportunities.
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    Wisdom Exchange Event was held at the MaRS Centre Feb 19, 2009. This event gathers leading growh firms and it is sponsored by the Ontario Government. Jason Myers, head of Canadian Manufacteurers & Exporters mentions the Canadian economy will get worse and last longer but there will be a list of business opportunities. Feb 19, 2009
Assunta Krehl

Samsung and the Economy - The Agenda - February 2, 2010 - 0 views

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    Watch MaRS cleantech advisor and practice lead, Tom Rand, as he appears on a panel on TVO's The Agenda with Steve Paikin. The issue: the Samsung deal - good for Ontarians or not? Other panelists on the Feb 2, 2010, show include: Randall Denley from the Ottawa Citizen; Kristopher Stevens from the Ontario Sustainable Energy Association; and Norm Rubin from Energy Probe.
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    With Steve Pakin host of The Agenda, Norm Rubin, Director of Nuclear Research, Randall Denley, Columnist with the Ottawa Citizen, Tom Rand, Cleantech Lead at the MaRS Discovery District, and Kristopher Stevens, Executive Director of the Ontario Sustainable Energy Association discuss the harnessing nature to boost Ontario's economy--what the Samsung deal means for Ontario.
Tim T

Climate change after Copenhagen: China's thing about numbers | The Economist - 0 views

  • overall aim: to move from a world in which carbon dioxide emissions are rising to one in which they are falling, fast enough to make a difference.
  • How fast is enough? A fair measure is carbon and other greenhouse emissions in 2050; if by that date they are only half their 1990 level, most people agree, then things would be on the right track. Another widely accepted calculation: if developing countries are to grow a bit between now and then, rich countries would need to slash emissions to a level at least 80% below what they were in 1990.
  • The numbers that China had resisted were those that could be read in any way as commitments.
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  • They secured the removal of language contained in early drafts that spoke of a Copenhagen deal as a step on the road to a legally binding treaty. As the world’s largest emitter (without which any agreement is dead), China was in a strong position, and it took full advantage.
  • China also gave some ground. It satisfied the Americans on one sticking-point: the principle of “monitoring, reporting and verification” of actions promised by developing countries.
  • Unless China, in particular, can be shown to live up to its promises, it will be very difficult to get a climate bill through America’s Senate.
  • And there is money on the table: an initial promise of $10 billion a year, for three years, from developed countries to help poorer states mitigate climate change and adapt to it.
  • Copenhagen Green Climate Fund
  • A bid to reinsert the notion of a future binding treaty was firmly quashed by China, India and Saudi Arabia.
  • the next full conference will be in Mexico on November 29th
June A

Business of Green - Venture Capitalists See Growth in Agriculture 2.0 - NYTimes.com - 1 views

shared by June A on 22 Apr 10 - Cached
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    agriculture "venture capital"
Assunta Krehl

Green elites meet the people - National Post - May 29, 2010 - 0 views

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    E(3) Canadian Roundtables took place May 26, 2010. The event featured a panel of thought leaders sharing their vision for a sustainable energy future for Canada. Tom Rand, Cleantech Advisor at the MaRS Discovery District spoke at the event.
Assunta Krehl

Meet The Next Round of Alternative Energy Innovators - Green Economy - August 25, 2011 - 0 views

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    Shawn Lesser states "The Global Cleantech Cluster Association (GCCA) have nominated 185 companies for 2011 GCCA Later Stage Award by 30 cleantech clusters from around the world."  The following 6 MaRS Cleantech clients have been nominated:  NIMTech, Hydrostor, Temporal Power, Hydrogenics, Morgan Solar and Sustainable Energy Technologies.
Assunta Krehl

Global Cleantech Cluster Late Stage Awards - Green Chip Stocks - October 12, 2011 - 0 views

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    HydroGenics, a MaRS Cleantech Client, made the Global Top 30 for the 2011 Later Stage Award. The Global Cleantech Cluster Assocication says the "winners in the 10 Later Stage Award categories will be receive international investment exposure."
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