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chemtronbio2018 on 17 May 18Infectious Mononucleosis (IM) is an acute, self-limiting disease caused by the Epstein-Barr virus (EBV). Infection with EBV in early life in adults usually is asymptomatic. Diagnosis of IM is based on the evaluation of characteristic clinical symptoms and serological changes. Serological diagnosis of IM has been demonstrated by the detection of heterophile and EBV specific antibodies. It is a widely accepted practice among physicians to use the detection of heterophile antibodies as an aid in the diagnosis of IM.