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An experimental Alzheimer's drug developed by Eli Lilly and Co slowed cognitive decline by 35% in a late-stage trial, the company said on Wednesday, providing what experts say is the strongest evidence yet that removing sticky amyloid plaques from the brain benefits patients with the fatal disease. Lilly's drug, donanemab, met all goals of the trial, the company said. It slowed progression of Alzheimer's by 35% compared to a placebo in 1,182 people with early-stage disease whose brains had deposits of two key Alzheimer's proteins, beta amyloid as well as intermediate levels of tau, a protein linked with disease progression and brain cell death. The study also evaluated the drug in 552 patients with high levels of tau and found that when both groups were combined, donanemab slowed progression by 29% based on a commonly used scale of dementia progression known as the Clinical Dementia Rating Scale (CDR-SB). Using that scale, experts said Lilly's findings were roughly on par with Eisai Co Ltd and Biogen Inc's lecanemab, sold under the brand name Leqembi, which reduced cognitive decline by 27% in patients with early Alzheimer's in a study published last year. The results drove Lilly's shares to a record high, up more than 6% at $429.85. Dr. Ronald Petersen, an Alzheimer's researcher at Mayo Clinic, said Lilly's trial is the third to show removing amyloid from the brain slows progression of the disease, which could put to rest some lingering doubts about the benefits of drugs in the class and the amyloid-lowering theory. "It's modest, but I think it's real," he said of the benefit, "and I think it's clinically meaningful." Dr. Erik Musiek, a Washington University neurologist at Barnes-Jewish Hospital, said the efficacy looks as good or better than lecanemab.

Malnutrition in Liver Disease: Diet Interventions for Optimal Outcomes is organized by Dietitian Central. Malnutrition is highly prevalent and associated with unfavorable outcomes in patients with liver disease. The involvement of a skilled dietitian early in the disease process is critical in order to prevent and treat multifactorial nutrition challenges.

I believe that 90% of our health depends on our diet, so if we are on a diet and not eating enough, it seems to be reasonable, I am also on a diet now https://betterme.world/articles/30-day-fast-weight-loss/, but I follow clear instructions and I feel very well

The UK Health Security Agency (UKHSA) has said that monkeypox is to be listed as a notifiable disease in law from Wednesday (June 8). The new legislation means all doctors in England are required to notify their local council or local Health Protection Team (HPT) if they suspect a patient has monkeypox. Laboratories must also notify the UKHSA if the monkeypox virus is identified in a laboratory sample. Wendi Shepherd, monkeypox incident director at UKHSA, said: "Rapid diagnosis and reporting is the key to interrupting transmission and containing any further spread of monkeypox. This new legislation will support us and our health partners to swiftly identify, treat and control the disease. "It also supports us with the swift collection and analysis of data which enables us to detect possible outbreaks of the disease and trace close contacts rapidly, whilst offering vaccinations where appropriate to limit onward transmission."

Early detection and treatment of Alzheimer's disease require the use of dependable and cost-effective screening technologies. Researchers at Sweden's Karolinska Institutet have revealed that the level of tau, a protein that plays a vital role in the development of severe dementia, is associated with a kind of sugar molecule in the blood. The study, which is published in Alzheimer's & Dementia, can pave the way for a simple screening procedure able to predict onset ten years in advance. "The role of glycans, structures made up of sugar molecules, is a relatively unexplored field in dementia research," says the study's first author Robin Zhou, medical student and affiliated researcher at the Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet. "We demonstrate in our study that blood levels of glycans are altered early during the development of the disease. This could mean that we'll be able to predict the risk of Alzheimer's disease with only a blood test and a memory test." In Alzheimer's disease, the neurons of the brain die, which is thought to be a result of the abnormal accumulation of the proteins amyloid beta and tau. Clinical trials for Alzheimer's drugs show that treatment should commence early in the pathological process, before too many neurons have died, to reverse the process before it is too late.

COVID 19 (Coronavirus Disease) is a contagious disease caused by a new kind of virus spread globally.

The global market for chronic kidney disease drugs is expected to witness single-digit growth during 2019-2025. The drug pipeline of chronic kidney disease looks promising with novel therapeutic approaches, such as cell therapy, likely to enhance the market growth opportunities. However, the competition from biosimilars and complex drug development processes are impeding the market growth. Over the period, extensive research is being done to fill the unmet needs' gap. The advances in the arena of regenerative treatment have come up with budding advancement of cell therapies that help regeneration and repairing of the kidneys. Cell therapy is proficient of refining the fundamental functioning capability of the kidney. Uncontrolled high blood pressure and diabetes are the leading causes of kidney failure globally.

The Department of Health and Social Care (DHSC) has invited views of healthcare professionals and others to tackle the six major health conditions which drive-ill health and contribute to the burden of disease in England. The six major health conditions - cancer; cardiovascular diseases including stroke and diabetes; chronic respiratory diseases; dementia; mental ill-health and musculoskeletal disorders - affect millions of people in England with data showing that one in four suffer from two or more of these major long-term conditions. Recognising the pressure these conditions are putting on the NHS, the government is seeking views on a new strategy to tackle them that will focus not only on treatment but also on prevention. Government is particularly interested in hearing from those who suffer from, care for or provide treatment to people who suffer from multiple long-term conditions. This is to ensure the Major Conditions Strategy is one that will better prevent, diagnose, manage and treat these conditions. Contributions are also encouraged from those working in NHS bodies, local government, the voluntary and community sector, and wider industry, on how best to tackle suffering from one or more of these major conditions. Particularly, it is seeking perspectives on how government and the NHS can work better together with different organisations and sectors to improve the nation's health.

Two new subvariants of Omicron - BA.4 and BA.5 - are spreading much faster than other corovanirus variants in Europe, which could lead to more hospitalisations and deaths as they become dominant, the EU's disease prevention agency said on Monday (June 13). Most EU countries have so far detected low rates of the two subgroups. But in countries where the proportion has risen - such as Portugal, where BA.5 accounted for 87 per cent of cases by May 30 - there have been surges in overall cases, according to the European Centre for Disease Prevention and Control (ECDC). The two sublineages were added to the World Health Organization's monitoring list in March and have also been designated as variants of concern by the ECDC. Variants BA.4 and BA.5 do not appear to carry a higher risk of severe disease than other forms of Omicron.But an increase in case numbers from higher transmission rates risks leading to an increase in hospitalisations and deaths, the agency said. "The growth advantage reported for BA.4 and BA.5 suggest that these variants will become dominant," ECDC said in a statement on its website.

Have you ever suffered from inflammation? If you have, chances are high that you do not want to suffer from it, ever again. Inflammation is a condition that plays a big role in a number of diseases- from cancer, to stroke, heart disease, autoimmune diseases and even diabetes! Recent research shows that there might be a link between inflammation and brain disorders as well. It's important for one to find out more about the ways through which they can get rid of this problem.

Creative Animodel researches on varieties and different ages of the animal's and developing some animodels and experiment on it. In this experiment our scientist are explore the disease condition, dose quaintly and other relevant information related to it.

Cerebral palsy-also known as CP-is a condition caused by injury to the parts of the brain that control our ability to use our muscles and bodies. Cerebral means having to do with the brain. Palsy means weakness or problems with using the muscles. Often the injury happens before birth, sometimes during delivery, or soon after being born. Physical symptoms typically appear in the first few years of life. Cerebral Palsy are frequently slow to reach developmental milestones such as learning to roll over, sit, crawl, smile, or walk. Cerebral Palsy occurs in 1 in every 300 children (Source: Center for Disease Control). CP can be mild, moderate, or severe. Mild CP may mean a child is clumsy. Moderate CP may mean the child walks with a limp. He or she may need a special leg brace or a cane. More severe CP can affect all parts of a child's physical abilities.Child with moderate or severe CP may have to use a wheelchair and other special equipment. Children with CP can also have learning problems, speech, problems with hearing or seeing (called sensory problems), intellectual differences, and behavioral or emotional challenges. Cerebral palsy does not always cause serious disabilities. Usually, the greater the injury to the brain, the more severe the CP. However, CP doesn't get worse over time, and most children with CP have a normal life span. Wheelchair Pediatric Pediatric Wheelchairs we offer are designed specifically for a wide range of children. All pediatric wheelchair can be configured with many accessories to meet your specific needs. Comfortable, sporty, and reliable.This is an ideal system for pediatric patients who require multiple tilt angles for pressure relief, digestion and fixed seat positions. Pediatric Chairs divided into three major categories.Pediatric Chairs isn't an official thing, but it helped me when I was comparing various models. The main categories are standard, tilt, and stroller-style. I suggest checking them all out to

Reclining Wheelchairs are specially designed to allow a person to comfortably recline at incremental angles safely and comfortably. Typically used for accommodation of severe hip extension contractures, or thostatic hypotension, and pressure re-distribution for prevention of skin breakdown. Recliner Wheelchairs work better with Elevating Legrests (ELRs); the user's legs and feet can also be re-positioned for maximum comfort and health benefits. The "ELRs" are optional on some models and standard on others. Be sure to ask about which type of ELR is best suitable for seating and position needs. On some wheelchairs this is an option so be sure to check the options and accessories when purchasing. Reclining Back Wheelchair( bed cum wheelchair ) which are suitable for indoor as well as outdoor purposes. These wheel chairs are manufactured using high quality material to ensure high strength and durability. Wheelchairs are available in foldable frames and are capable for maximum weight. Reclining wheelchairs are available in standard folding frames with extended head supports and seat widths up to 24" wide. The recline mechanism is attendant operated with levers much like a bicycle brake lever. The levers operate hydraulic (pump) mechanisms for a smooth adjustment. Using this reclining mechanism, the chair back can easily and frequently be positioned to any angle. Flexible Back Positioning: Reclining chairs offer unlimited back re-positioning for more patient comfort, better blood circulation, and to aid in sleeping. Work best with ELRs: Recliner chairs need Elevating Legrest so the patients legs and feet can also be re-positioned for maximum comfort. On some chairs this is an option so be sure to check the options and accessories section of each product page. Only the Back moves: On recliner wheelchairs the back reclines but the seat bottom stays in-place. Karma Aurora 4 Reclining Wheelchair: Frame Style : Fordable Frame Material : Aluminium (

According to the latest findings from the Centers for Disease Control (CDC), cardiovascular disease-an umbrella term that includes heart attacks, stroke, arrhythmia and several other conditions-is the leading cause of death in the United States. Of course, many things can contribute to the formation of cardiovascular disease, including genetics and countless lifestyle choices.

Common nephrology urology causes, diseases, and conditions; Find information on different types of nephrology urology disease symptoms, problems and risks.

Huntington's disease in children is not uncommon. This is a genetic disorder, that is, a child with a parent with HD will have a 50% chance of inheriting the disease.

Nowadays, the problem of chronic kidney disease ie kidney failure is increasing rapidly. In recent research, it has been reported that people are being victim of this disease because they do not know the symptoms of kidney failure. At the right time, it can be treated if you know the cause of the disease.

Premature ejaculation is a condition of losing the ability to control and maintain ejaculation reflexes in men when having sexual activity, thereby causing ejaculation even though it is not time to ejaculate, the consequences will create frustration, disappointment for one or both men and women. This problem can affect the happiness and happiness of both and is often called "not going to the market has run out of money". This pathology needs to be treated to fix it on a case-by-case basis. Premature ejaculation may be due to psychological and physical causes. In terms of psychological causes, in order to have a normal sexual intercourse between men and women at Men's Health Clinic, there must be a smooth balance between the excitement and inhibition processes; when excessive excitement can lead to premature ejaculation; In fact, masturbation in long-term men can form a reflex of conditional premature ejaculation, which in turn leads to premature ejaculation during actual sexual intercourse. Regarding the entity, there are many different causes such as: there is an increased sensitivity of the penis, pelvic inflammatory diseases, some endocrine disorders including hypogonadism, male sexual abstinence, increased blood prolactin ... Men's Health Clinic in Viet Nam can affect the function of penis erection and ejaculation function; There is also the hypothesis that serotonin receptors increase susceptibility, serotonin receptor hypersensitivity include 5-HT2C (5-hydroxytryptamine receptor 2C) receptors and 5-HT1A (5-hydroxytryptamine receptors). 1A) in the central nervous system can lead to premature ejaculation that has been accepted by many scientists. Source: Men's Health Clinic Viet Nam First, we have to ask about the disease that is acquired because the diagnosis of premature ejaculation is mainly based on the question. Questions can be divided into groups such as: Questions for diagnosis are set about how long ejaculation takes? Intravaginal ejaculation latency t

When emotion is so strong it will definitely have some side effects too. Side effects are nothing but the diseases that are caused through over flood of some emotions in ourselves.