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Gut Conditions & Parkinson's: Groundbreaking Link Revealed - 0 views

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    Digestive issues such as constipation, dysphagia and irritable bowel syndrome (IBS) may be precursors of Parkinson's disease, according to research published in the journal Gut. Gastrointestinal symptoms are thought to precede the development of some cerebrovascular disease, including brain aneurysm or Alzheimer's disease, and it has been suggested (Braak's hypothesis) that gut conditions may precede the development of Parkinson's disease too. To test this hypothesis, researchers used data from a US nationwide medical record network (TriNetX) to compare 24,624 people who had been diagnosed with Parkinson's disease of unknown cause with those who had been diagnosed with other neurological conditions - Alzheimer's disease (19,046) or cerebrovascular disease (23,942) - or with none of these (24,624; comparison group).
pharmacybiz

Alzheimer disease : New insights on treatment - 0 views

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    According to Alzheimer's Disease International, more than 55 million people worldwide will have Alzheimer's disease by 2020. This figure will nearly double every 20 years, reaching 78 million in 2030 and 139 million in 2050. The WHO Global Status Report for 2021 estimated the yearly global cost of dementia to be more than USD 1.3 trillion, with a projected increase to USD 2.8 trillion by 2030. To date most drugs developed to treat Alzheimer's disease have failed, largely because they target wrong biomarkers and individuals already exhibiting signs of the disease. Once symptoms appear, however, many brain cells responsible for memory and cognition are likely already damaged and beyond repair. Professor Shai Rahimipour in the Chemistry Department at Bar-Ilan University in Israel has pioneered a different approach utilizing theranostics to pinpoint and treat the earliest, pre-symptomatic signs of Alzheimer's disease. Showing promise in stopping progression of the disease before onset of irreversible brain cell damage, Rahimipour's groundbreaking approach has garnered significant attention in the scientific world.
pharmacybiz

Chiesi Farmaceutici acquires Amryt Pharma - 0 views

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    Chiesi Farmaceutici, the international, research-focused biopharmaceuticals and healthcare group has acquired Amryt Pharma, a global biopharmaceutical company dedicated to developing novel treatments for rare diseases. More than 300 million people worldwide are affected by rare diseases, including those who are living with ultra-rare metabolic and dermatologic conditions who still have no approved treatment. The acquisition reinforces Chiesi's commitment to deliver innovative treatments to patients with highly unmet medical needs. As a benefit corporation and a B Corp, Chiesi strives to create a world where it is common to have a therapy for all diseases and acts as a force for good, for society and the planet. Chiesi's Head of Chiesi Global Rare diseases Giacomo Chiesi commented: "We are excited to add the Amryt family to our company in this acquisition that demonstrates our commitment to rare diseases and aligns with our growth strategy through partnerships beyond internal research and development." Chiesi's new CEO Giuseppe Accogli said: "By joining forces and expertise we will be able to grow our capabilities and further strengthen our position to provide a positive impact on patients living with rare diseases." With regard to the financing of the deal, cash consideration has been partially financed through a EUR 700m syndicated loan led by BNP Paribas and Crédit Agricole as Global Coordinators and ESG Structuring Banks, acting alongside BPER and Deutsche Bank as Mandated Lead Arrangers. Crédit Agricole is Loan Agent too. Lenders have been advised by Clifford Chance, while Baker and McKenzie has assisted Chiesi Farmaceutici.
Vaughn Tobes

A Specific Kidney Disease Diet Will Reverse Kidney Disease - 2 views

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    A kidney disease diagnosis should not be taken as the close of a person's chapter in life, as a specific kidney disease diet will help reverse this disease. There are many people who are living with these types of kidney problems and live a normal life because they have found a way to manage the
Vaughn Tobes

Reverse Kidney Disease with a Kidney Disease Diet | RenalKidneyProblems.com - 0 views

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    A kidney disease diet is for those who suffer from kidney disease, also called renal failure, which means that your kidneys cannot get rid of the waste in your blood. This waste is brought about by the foods that you eat everyday and therefore to make the work of the kidneys easier, you need to incorporate the best kidney disease diet.
pharmacybiz

AstraZeneca to stop developing Crohn's disease drug - 0 views

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    British drugmaker AstraZeneca said on Thursday (June 1) it would stop developing its drug brazikumab to treat inflammatory bowel diseases, including Crohn's disease and ulcerative colitis. The company said the discontinuation was due to a delay in the drug's development timeline, affected by global events and "the context of a competitive landscape". AstraZeneca regained the rights to brazikumab from Allergan in 2020 following U.S. drugmaker AbbVie's $63 billion tie-up with Allergan. AbbVie will stop funding the drug's development, AstraZeneca said. AbbVie's Skyrizi also treats Crohn's disease.
Vaughn Tobes

Fatty Liver Disease - 0 views

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    Nonalcoholic fatty liver disease is common and, for most people, causes no signs and symptoms and no complications. But in some people with nonalcoholic fatty liver disease, the fat that accumulates can cause inflammation and scarring in the liver. This more serious form of nonalcoholic fatty liver disease is sometimes called nonalcoholic steatohepatitis. At its most severe, nonalcoholic fatty liver disease can progress to liver failure.
fnfdoc

Cancer A Leading Chronic Disease And Prevention | Your Health Our Priority - 0 views

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    A cancer registry is the cancer cases which are registered in a population or specific country. In whole world mortality rate due to cancer is 20%. In USA cancer is the second largest disease of causing death after heart disease. Recently in 2016 estimated that 595,690 people die from this disease according to cancer statistics of National Cancer Institute USA.
fnfdoc

What Is Leprosy Disease? | Health Blog - 0 views

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    What Is Leprosy Disease? Leprosy is a chronic, granulomatous infection caused by the... According to historical records, this disease spread through the slave trade and migration routes from... In this article, we talk about the causes, symptoms, and treatment of Leprosy
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    Like TB, leprosy is caused by a bacterium. The bacterium is Mycobacterium Leprae. It was discovered by Armauer Hansen in Norway in 1873. This is why it is also called Hansen's disease. Although its bacterial nature was known at the time, it was not considered infectious.
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    Like TB, leprosy is caused by a bacterium. The bacterium is Mycobacterium Leprae. It was discovered by Armauer Hansen in Norway in 1873. This is why it is also called Hansen's disease. Although its bacterial nature was known at the time, it was not considered infectious.
pharmacybiz

Alzheimer's:Next frontier for Novo Nordisk - 0 views

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    Diabetes drugs that also promote weight loss such as Novo Nordisk's Ozempic, becoming a darling of celebrities and investors, are being studied to tackle some of the most difficult-to-treat brain disorders, including Alzheimer's disease. Diabetes regimens, from Ozempic to old mainstays like insulin and metformin, appear to address several different aspects of the metabolic system implicated in Alzheimer's disease, including a protein called amyloid and inflammation, researchers say. The hope is that improving glucose utilisation and tamping down inflammation in the entire body - including the brain - could slow progression of debilitating diseases like Alzheimer's and Parkinson's. Several scientists interviewed by Reuters news agency pointed to mounting research supporting testing diabetes drugs against neurodegenerative diseases. Results are years away and success uncertain. But interest has been buoyed by recent positive data on Alzheimer's drugs developed by Eisai with partner Biogen and by Eli Lilly demonstrating that removing sticky amyloid plaques accumulated in the brain can slow cognition decline caused by the fatal mind-wasting disease. Those successes followed decades of futility that had left many questioning the validity of the amyloid theory behind most experimental Alzheimer's drugs.
Tom Willis

8 Ways to Determine the Extent of Gum Disease - 0 views

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    Most people do not realize that gum disease is the number one problem that we treat as dentists, not cavities. Eighty percent of the American population has some sort of gum disease, the early stages of which is gingivitis. This is when the gums become swollen, sore, and bleed. One needs to act beforehand to get rid of such problems.
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    Most people do not realize that gum disease is the number one problem that we treat as dentists, not cavities. Eighty percent of the American population has some sort of gum disease, the early stages of which is gingivitis. This is when the gums become swollen, sore, and bleed. One needs to act beforehand to get rid of such problems.
themed guru

Risk of heart disease by IBD - 0 views

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    As per a new study, Inflammatory bowel disease can result into heart disease.
Vaughn Tobes

Awareness of the Kidney Disease Symptoms in Women | RenalKidneyProblems.com - 0 views

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    What you need to know about kidney disease symptoms in women: A kidney infection is the worst disease for your body. It is not only dangerous, but also very painful.
Dr AGK Gokhale

What is Heart Disease? Symptoms, Causes and Prevention Treatment for Heart - 0 views

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    Heart disease is any disorder that affects the hearts ability to function normally and there are different diseases. Here are symptoms, causes and prevention treatment for heart diseases
pharmacybiz

Alcohol Consumption During Pandemic Led Liver Disease: Study - 0 views

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    Researchers have projected the rates of liver disease and associated deaths due to increased alcohol consumption during the Covid-19 pandemic. The research has been published in the 'Hepatology Journal'. A team led by investigators at Massachusetts General Hospital used data from a national survey of US adults on their drinking habits that found that excessive drinking (such as binge drinking) increased by 21 per cent during the Covid-19 pandemic. The scientists simulated the drinking trajectories and liver disease trends in all US adults. They estimated that a one-year increase in alcohol consumption during the Covid-19 pandemic will result in 8,000 additional deaths from alcohol-related liver disease, 18,700 cases of liver failure, and 1,000 cases of liver cancer by 2040. In the short term, alcohol consumption changes due to Covid-19 are expected to cause 100 additional deaths and 2,800 additional cases of liver failure by 2023. The researchers noted that a sustained increase in alcohol consumption for more than one year could result in 19-35 per cent additional mortality.
Anatoliy Simeonov

Flu symptoms 2013 What is flu and How do you catch him - 0 views

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    The flu is an acute infectious disease of viral etiology. Flu symptoms are fever, cough, headache and muscle aches. It spreads easily from person to person, it circulates around the world and can affect everyone - from the youngest to the elderly and cause epidemics and pandemics. Disease known since ancient times. There is evidence that humanity has experienced so far over 30 flu pandemics, and only in the last century, there were three. The most serious of these, so called. "Spanish flu", founded in 1918, has led to the deaths of 20-50 million people. The flu virus belongs to the family Orthomyxoviridae, that there is only one race - Influenzavirus, including viruses causing disease in humans, mammals and birds. Some flu strains are species specific (infect only certain species, or only the people), but there are strains of flu that can spread from animal species to humans. Famous 3 types of flu virus - type A, type B and C. Influenza type C viruses, although similar in morphology differs from the other two types of the antigen and other basic properties. Influenza C occurs sporadically and causes respiratory disease with a slight leakage. Viruses that cause seasonal epidemics are of type A and type B. The most volatile are type A flu virus
Vaughn Tobes

Awareness of the Kidney Disease Symptoms in Women - Health - Diseases and Conditions - 0 views

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    What you need to know about kidney disease symptoms in women: A kidney infection is the worst disease for your body. It is not only dangerous, but also very painful. It can happen to anyone but the result and symptoms vary.
Dr AGK Gokhale

Top 10 Cardiovascular Disease Myths | cardiovascular disease myths - 0 views

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    Cardiovascular disease kills more people each year than any other disease. How much do we really know about our heart’s health? Learn heart disease myths and facts published in doctor Gokhale website.
pharmacybiz

Good cholesterol level:Predictive value varies by race - 0 views

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    The widely-held concept that levels of "good" cholesterol in the blood can indicate heart disease risk is not equally true for Blacks and whites, and the measure itself may be of less value than previously thought, according to a U.S. study published on Monday (November 21). Various types of cholesterol are thought to have either healthy or unhealthy effects. Low levels of so-called "good" high-density lipoprotein (HDL) cholesterol were linked with higher odds for developing cardiac problems in the long-term study - but only in white participants, the study published in the Journal of the American College of Cardiology found. In contradiction to what has generally been assumed, low HDL levels did not confer any higher risk of heart disease in Black people, researchers said. Among white people, however, those with HDL levels below 40 milligrams per deciliter had a 22% higher risk for coronary heart disease compared with those whose HDL levels were higher. High HDL levels (above 60 mg/dL), which are thought to be protective, were not linked with lower coronary heart disease risks in either race, researchers found.
pharmacybiz

Alzheimer success research unlocks hope for future therapies - 0 views

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    The first big breakthrough in 30 years of Alzheimer's research is providing momentum for clinical trials of "cocktail" treatments targeting the two hallmark proteins associated with the mind-robbing disease, according to interviews with researchers and pharmaceutical executives. Drugmakers Eisai and Biogen reported in September that their therapy lecanemab could slow progress of the disease by 27% over 18 months compared with a placebo. The finding validates the theory that clearing the amyloid protein that forms clumps in the brains of Alzheimer's patients could slow or halt the disease and has strengthened the support from some scientists for simultaneously targeting another notorious protein linked to Alzheimer's: tau. Eisai and Biogen are scheduled to present full data from their lecanemab study on Tuesday at the Clinical Trials on Alzheimer's Disease conference in San Francisco. The U.S. Food and Drug Administration is expected to make a decision by early January on the companies' application for accelerated approval. If approved on an accelerated basis, the companies said they would immediately apply for full U.S. regulatory approval which could help secure Medicare coverage.
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