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Matti Narkia

Green tea 'slows prostate cancer' - BBC NEWS | Health - 0 views

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    A chemical found in green tea appears to slow the progression of prostate cancer, a study has suggested.
    Green tea has been linked to a positive effect on a wide range of conditions, including heart disease, cancer and Alzheimer's disease.
Matti Narkia

White button mushroom phytochemicals inhibit aromatase activity and breast cancer cell ... - 0 views

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    White button mushroom phytochemicals inhibit aromatase activity and breast cancer cell proliferation.
    Grube BJ, Eng ET, Kao YC, Kwon A, Chen S.
    J Nutr. 2001 Dec;131(12):3288-93.
    PMID: 11739882
Matti Narkia

Anti-aromatase activity of phytochemicals in white button mushrooms (Agaricus bisporus)... - 0 views

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    Anti-aromatase activity of phytochemicals in white button mushrooms (Agaricus bisporus).
    Chen S, Oh SR, Phung S, Hur G, Ye JJ, Kwok SL, Shrode GE, Belury M, Adams LS, Williams D.
    Cancer Res. 2006 Dec 15;66(24):12026-34.
    PMID: 17178902
    doi: 10.1158/0008-5472.CAN-06-2206
Matti Narkia

White button mushroom (Agaricus bisporus) exhibits antiproliferative and proapoptotic p... - 0 views

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    White button mushroom (Agaricus bisporus) exhibits antiproliferative and proapoptotic properties and inhibits prostate tumor growth in athymic mice. Adams LS, Phung S, Wu X, Ki L, Chen S.
    Nutr Cancer. 2008;60(6):744-56. n
    PMID: 19005974
Matti Narkia

Herb & Supplement Encyclopedia: Flora Health Canada - 0 views

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    We have compiled an Herb and Supplement Encyclopedia that you can search through to learn more about natural remedies.

    This herbal and supplement encyclopedia was written in an effort to provide accurate and up to date information on herbs that are commonly used in herbal preparations within Canada and the United States. Covering both their traditional usage and the latest scientific findings, each herbal monograph lists the 'traditional' usages in point form and also outlines the most well founded indications and relevant research in a short overview paragraph.

    The information on indications and suggested amount for each herb is largely based on the German Pharmacopoeia and other authoritative sources. We have also listed the traditional use of these herbs by First Nations healers wherever possible, out of respect and great appreciation for their healing wisdom and insight, often born out by science.
Matti Narkia

Sloan-Kettering - Garlic - 0 views

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    Derived from the bulb or clove of the plant. Garlic is used as a spice and to treat hyperlipidemia, hypertension, atherosclerosis, cancer, and infections. Processing can have a substantial effect on the chemical content in garlic; the volatile oil components are sensitive to heat and certain enzymes are acid-labile. Several oral garlic formulations are available, and clinical studies have addressed a variety of the proposed claims. Placebo-controlled trials on the cholesterol lowering effect of garlic yielded mixed results (16) (17) (18) (21) (22) (26). Studies evaluating the antithrombotic effects repeatedly have shown modest reduction in platelet aggregation, but varying levels of fibrinolytic activity. Research shows mixed effects with regard to reductions in blood glucose, blood pressure, or risk of cardiovascular disease (23). Frequently reported adverse events include bad breath, headache, fatigue, GI upset, diarrhea, sweating, and possible hypoglycemia (9). Because garlic is known to decrease platelet aggregation and potentially elevate the INR, it should not be used with anticoagulants or in patients with platelet dysfunction (15). Garlic appears to induce cytochrome p450 3A4 and may enhance metabolism of many medications (e.g. cyclosporin and saquinavir) (12). An analysis of several case-control studies in Europe suggests an inverse association between garlic consumption and risk of common cancers (25).
Matti Narkia

Study Demonstrates That AHCC(R) Provides Immune Enhancement Against The West Nile Virus - 0 views

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    A recently completed study from researchers at Colorado State University supported by the Division of Vector-Borne Infectious Diseases with the Centers for Disease Control and Prevention (CDC) has demonstrated that AHCC(R) (Active Hexose Correlated Compound) enhances host resistance by boosting protective immune responses specific to the West Nile Virus.

    Since its discovery in the United States in 1999, infections caused by the West Nile Virus have become a major public health concern. West Nile Virus is caused by people being bitten by mosquitoes infected with the virus. According to the CDC, there have been 28,018 reported cases with 1,092 deaths since 1999. In 2003, the highest number of cases was reported at nearly 10,000. Currently there is no effective treatment for the disease.
Matti Narkia

Supplementation with active hexose correlated compound increases survival following inf... - 0 views

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    Supplementation with active hexose correlated compound increases survival following infectious challenge in mice.
    Ritz BW.
    Nutr Rev. 2008 Sep;66(9):526-31. Review.
    PMID: 18752476
    DOI: 10.1111/j.1753-4887.2008.00085.x
Matti Narkia

Active Hexose Correlated Compound shown to enhances immune system by increasing product... - 0 views

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    A recently published study in Nutrition and Cancer (60(5), 643-651) by researchers at Kansai Medical University in Osaka, Japan has shown that AHCC (Active Hexose Correlated Compound) enhances immune function by increasing the number of dendritic cells (DCs).

    DCs are a key part of the immune system responsible for presenting foreign substances to other immune system cells.

    The study was conducted in a double-blind randomized fashion where twenty-one healthy subjects received a placebo or AHCC at 3.0 g/day for 4 weeks. Blood samples were obtained and measured at baseline and at 4 weeks. The number of circulating types of DCs was measured which included CD 11c+ DCs (myeloid DC population; DC1) and CD11c- DCs (lymphoid DC population; DC2). Other parameters measured included mixed-leukocyte reaction (MLR), natural killer (NK) cell activity, the proliferative response of T lymphocytes toward mitogen (phytohemagglutinin [PHA]) and cytokine production of interleukin (IL)-2, IL-4, IL-6, IL-10, interferon gamma-gamma, and (alpha)-tumor necrosis factor.
Matti Narkia

Oral administration of active hexose correlated compound enhances host resistance to We... - 0 views

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    Oral administration of active hexose correlated compound enhances host resistance to West Nile encephalitis in mice.
    Wang S, Welte T, Fang H, Chang GJ, Born WK, O'Brien RL, Sun B, Fujii H, Kosuna K, Wang T.
    J Nutr. 2009 Mar;139(3):598-602. Epub 2009 Jan 13.
    PMID: 19141700
    doi:10.3945/jn.108.100297
Matti Narkia

Active hexose correlated compound acts as a prebiotic and is antiinflammatory in rats w... - 0 views

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    Active hexose correlated compound acts as a prebiotic and is antiinflammatory in rats with hapten-induced colitis.
    Daddaoua A, Martínez-Plata E, López-Posadas R, Vieites JM, González M, Requena P, Zarzuelo A, Suárez MD, de Medina FS, Martínez-Augustin O.
    J Nutr. 2007 May;137(5):1222-8.
    PMID: 17449585
Matti Narkia

Sloan-Kettering - AHCC - 0 views

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    A proprietary extract prepared from co-cultured mycelia of several species of Basidiomycete mushrooms, including shiitake (Lentinus edodes), active hexose correlated compound (AHCC) is extracted from mushrooms using hot water following an enzyme pretreatment, but specific mushroom source and preparation details have not been fully disclosed. Patients use this to prevent and treat cancer. Animal studies suggest that AHCC has antioxidant effects and may protect against disorders induced by oxidative stress (1) and may also enhance resistance against bacterial (2) (7)and viral infections (3). In healthy humans, AHCC increased dendritic cell number and function (4)

    In vitro and animal studies show that AHCC exhibits some anticancer activities, but the results of these studies are vague
Matti Narkia

Active Hexose Correlated Compound - Wikipedia, the free encyclopedia - 0 views

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    Active Hexose Correlated Compound (AHCC) is an alpha-glucan rich nutritional supplement produced from the mycelia of shiitake (Lentinula edodes) of the basidiomycete family of mushrooms, and should not be confused or used as a drug or medicine.[1][2] AHCC was originally designed to lower high-blood pressure. However, researchers at Tokyo University found AHCC's influence upon the innate immune system highly beneficial and published the results in 1992, though not in the commonly indexed scientific literature. In this study, researchers found that AHCC significantly increased natural killer (NK) cell activity in cancer patients, and also enhanced the effects of killer T-cells, and cytokines (interferon, IL-12, TNF-alpha
Matti Narkia

Button mushrooms contain as much anti-oxidants as expe... ( The humble white button mus... - 0 views

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    The humble white button mushroom (Agaricus bisporus) has as much, and in some cases, more anti-oxidant properties than more expensive varieties.
Matti Narkia

White Button Mushroom (Agaricus Bisporus) Exhibits Antiproliferative and Proapoptotic P... - 0 views

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    White button mushroom (Agaricus bisporus) exhibits antiproliferative and proapoptotic properties and inhibits prostate tumor growth in athymic mice.
    Adams LS, Phung S, Wu X, Ki L, Chen S.
    Nutr Cancer. 2008;60(6):744-56.
    PMID: 19005974
    DOI: 10.1080/01635580802192866
Matti Narkia

Definition of white button mushroom extract - National Cancer Institute Drug Dictionary - 0 views

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    A heat-stable extract of white button mushrooms (Agaricus bisporus) with potential chemopreventive and immunomodulating activities. Phytochemicals, such as polysaccharides and especially beta-D-glucans found in the white button mushroom extract, bind to and inhibit the activity of aromatase, an enzyme responsible for the conversion of androgens to estrogens and which is often upregulated in breast cancer cells. The consequent decrease in estrogen production may result in the suppression of estrogen-dependent cellular proliferation. In addition, this extract may promote dendritic cell (DC) maturation, increase interferon gamma (IFN-gamma) and tumor necrosis factor alpha (TNF-alpha) production, and may enhance natural killer (NK) cell activity, thus amplifying both innate and T cell-mediated immune responses against cancer cells. Check for active clinical trials or closed clinical trials using this agent.
Matti Narkia

Eating mushrooms may boost immune system (ASU Research) - 0 views

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    Edible mushrooms are a versatile functional food and have been touted as a way to preserve youth, longevity and overall health for centuries. Now nutrition researchers from Arizona State University and Pennsylvania State University are finding that they may even help boost the immune system and reduce inflammation, especially in the colon.

    Keith R. Martin, ASU assistant professor in nutrition, along with his Penn State colleagues, experimented with various types of mushrooms, from the more common white button to the exotic like shiitake and oyster, to see what sort of effect they had on the immune system. Their paper was published in late February in BMC Immunology, a peer reviewed online journal.

    "We found that the white button mushroom seemed to be the most effective in boosting the immune system, which is good because they are the most affordable," said Martin.
Matti Narkia

White button mushrooms appear to boost immune function - Tufts Journal: Briefs: Healthy... - 0 views

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    White button mushrooms appear to boost immune function

    It appears that a little fungus may be good for what ails you. That's the conclusion of a new study that found that eating white button mushrooms may boost the immune system and protect against infection.

    If the research, done on animals, translates to people, it could raise the health-benefit profile of the fungus, which also contains high concentrations of the super-antioxidant ergothioneine, which protects cells from damaging free radicals.

    "This is the first published study showing the effect of white button mushrooms on immune function," Dayong Wu, a scientist in the Immunology Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts and lead author of the study, published in the June issue of the Journal of Nutrition, told NutraIngredients.com.

    The research also suggests that the mushroom may boost both innate and acquired immune system health. The innate immune system, the one you're born with, is the body's first line of defense. The acquired immune system revs up if a pathogen makes its way past the innate system and customizes the immune response to target the invader.
Matti Narkia

Clinical Trial Results Show Proof-of-Concept For Use Of Coriolus Versicolor As Immunonu... - 0 views

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    The results of a year long clinical trial examining the effects of mushroom supplementation in patients with Human Papillomavirus (HPV) have recently been presented at congress. Dr. Jose Silva Couto and Dr. Daniel Pereira da Silva of the Cervical Pathology Unit of the Portuguese Institute of Oncology in Coimbra, Portugal presented their findings at the 20th European Congress of Obstetrics and Gynaecology, in Lisbon Portugal. This study provides a promising set of results and demonstrates proof-of concept for the question as to whether immunonutrition supplements can be successfully used to improve HPV status in patients.
Matti Narkia

Ginger inhibits cell growth and modulates angiogenic factors in ovarian cancer cells - ... - 0 views

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    Ginger inhibits cell growth and modulates angiogenic factors in ovarian cancer cells.
    Rhode J, Fogoros S, Zick S, Wahl H, Griffith KA, Huang J, Liu JR.
    BMC Complement Altern Med. 2007 Dec 20;7:44.
    PMID: 18096028
    doi:10.1186/1472-6882-7-44
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