The concept of gene transfer between cells first existed in bacteria; they are capable of at least four natural forms of genetic exchange. The genetic transfer technique is used very widely in basic research and applied biology. The delivery of DNA into an animal cell is a very established and fundamental procedure. It has become a very crucial tool for gene cloning, the study of gene function and the regulation and production of small amounts of recombinant proteins for analysis and verification. It helps to express the introduced genetic construct in the recipient cells or inactivate particular endogenous genes.
The concept of gene transfer between cells first existed in bacteria; they are capable of at least four natural forms of genetic exchange. The genetic transfer technique is used very widely in basic research and applied biology. The delivery of DNA into an animal cell is a very established and fundamental procedure. It has become a very crucial tool for gene cloning, the study of gene function and the regulation and production of small amounts of recombinant proteins for analysis and verification. It helps to express the introduced genetic construct in the recipient cells or inactivate particular endogenous genes.
If you are looking for a source of cost-effective and high-quality research instruments so you can focus on your scientific journey? Let WPI be your trusted partner as you stock your research laboratory with equipment, surgical instruments, and supplies. Cited in 1000s of notable publications over the last 50 years, WPI offers quality and value to biomedical researchers. Whether you study cell and tissue biology, animal physiology, electrophysiology or perform small animal surgery.
WPI's surgical instrumentation offering includes over 1,400 individual Instruments and 11 pre-assembled surgical-specific kits, which are designed for select surgical protocols. WPI also offers researchers and veterinarian surgeons the opportunity to build custom surgical kits for their own needs. WPI's quality line of surgical instruments is made of German steel with German craftsmanship, and it is constructed to our exact specifications. To match the quality of our German line, WPI's intermediate line of surgical instruments also goes through proper passivation with electrolytic polishing. The quality material and craftsmanship used in this line gives you the performance you demand at an economical price. WPI strives to provide you with quality instruments at cost-effective prices so you get more for less.
WPI offers surgical instruments and accessories for various applications:
* Micro or spring scissors for the dissection of soft tissues, blood vessels, nerve, and ophthalmic procedures
* Thumb forceps for compressing or grasping tissues in surgical procedures and handling sterile dressings
* Hemostatic forceps to control bleeding in many surgical procedures
In addition, WPI also offers surgical adhesives for wound closures, sterilizers and cleaners, and various accessories needed for surgery including biopsy punches, ear punches, loupes, micro drills and more. Surgical instruments need to be sterilized before use to prevent infection. WPI offers a vast range of steril
Gene transfer technique is used very frequently both in basic research and applied biology. The delivery of DNA into animal cells is a fundamental and fixed procedure. It has become anecessary tool for gene cloning, the study of gene function and regulation and the production of small amounts of recombinant proteins for analysis and verification. Gene transfer experiment helps to launch the genetic construct (or transgene) in the recipient cells or to disrupt or inactivate particular endogenous genes resulting in a loss of function. There are many utilizations of gene-transfer like large-scale commercial production of recombinant antibodies and vaccines and gene medicine or gene therapy. They range from the use of mammalian and insect cell cultures to transfer of DNA into human patients for the correction or prevention of disease.
WPI's surgical instrumentation offering includes over 1,400 individual Instruments and 11 pre-assembled surgical-specific kits, which are designed for select surgical protocols. WPI also offers researchers and veterinarian surgeons the opportunity to build custom surgical kits for their own needs. WPI's quality line of surgical instruments is made of German steel with German craftsmanship, and it is constructed to our exact specifications. To match the quality of our German line, WPI's intermediate line of surgical instruments also goes through proper passivation with electrolytic polishing. The quality material and craftsmanship used in this line gives you the performance you demand at an economical price. WPI strives to provide you with quality instruments at cost-effective prices so you get more for less.
WPI offers surgical instruments and accessories for various applications:
* Micro or spring scissors for the dissection of soft tissues, blood vessels, nerve, and ophthalmic procedures
* Thumb forceps for compressing or grasping tissues in surgical procedures and handling sterile dressings
* Hemostatic forceps to control bleeding in many surgical procedures
In addition, WPI also offers surgical adhesives for wound closures, sterilizers and cleaners, and various accessories needed for surgery including biopsy punches, ear punches, loupes, micro drills and more. Surgical instruments need to be sterilized before use to prevent infection. WPI offers a vast range of sterilization baskets and trays for use with surgical instruments and other tools.
"The new WPI MICRO-ePORE™ pinpoint cell penetrator is a simple and versatile system that can be used for efficient microinjection of a diverse array of compounds and biomolecules into oocytes and pre-implantation stage mammalian embryos. Patent pending Flutter Electrode Technology assists in small, clean, precise membrane penetration without tearing or damaging the membrane.
Benefits
Increase viability of injected embryos
Flexible system
Integrates with WPI's PV820/PV830, as well as other popular microinjection systems, like the Eppendorf Femtojet® and the Narishige injectors (Femtojet® 4I is a registered Trademark of Eppendorf.)
Microinjection of diverse compounds and biomolecules - DNA, RNA, proteins
Pre- and post-implantation in embryos of various species - mice, rodents, monkeys, bovine, pigs, zebrafish, etc.
Easy to operate - Hands-free operation with foot switch control
User adjustable frequency and voltage - four programmable protocols
Small, portable unit saves precious benchtop space
Works with all major inverted microscopes"
A transgenic animal is one whose genome has been altered by the transfer of a gene or genes from another species. In biomedical research, in the laboratory, transgenic animals are routinely used as models. Over 95 percent of those users are genetically modified rodents, predominantly mice. Transgenic animals have many Utilities which made them much superior to the normal animals.
Utilities of Transgenic Animals:
* During medical research, transgenic animals are mostly used to identify the functions of some specific factors in complex homeostatic systems. These can be through the over- or under-expression of a modified gene (the inserted transgene).
* In the toxicology as the responsive test animals for the detection of toxicants.
* In mammalian developmental genetics.
* In molecular biology, this analysis of the regulation of the gene expression, make use of the informative evaluation of some specific genetic change, at the level of the whole animal.
* While in the pharmaceutical industry, for the targeted production of pharmaceutical proteins, and during the drug production also on the product efficacy testing.
* In biotechnology, as producers of specific proteins.
* For the genetically engineered hormones to increase milk yield, meat production.
* In the cloning procedures to reproduce some specific bloodlines in the genetic engineering of the livestock, and in the aquaculture that affects the modification of animal physiology and/or anatomy,
* Developing animals specially created for use in xenografting.
Pubrica has extensive experience in developing a detailed clinical case report Writing Services that highlights the scientific documentation of a single clinical