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Cell manipulation using optical traps was first indicated by Bell Laboratories using visible argon laser light and infrared light. Movement of a micron-sized dielectric particle is convinced by the direct transfer of photon momentum to a non-absorbing particle during refraction and reflection, which is the radiation pressure. The optical force from a high intensity focused Gaussian profile laser has scattering (the process in which electromagnetic radiation or particles are deflected diffused.) and gradient force components, which gives a valid point of stable equilibrium near the beam focus. Particles are trapped being across by the gradient force, while around an axis motion of the particle is controlled by the scattering forces. The wavelength of light (dp>> λ) is less than for cells, ray optics have been used to derive the radiation force from scattering of the incident light momentum.

Cell manipulation is mainly done with the purpose of shaping and manipulating the gene in the cells of the organism and even to change the functioning of the cells.

Microinjection is a method where the foreign DNA transfers between the animals. A transgenic animal is one whose genome has been altered by the transfer of the genes from another species or breed....

Surgical tweezers are one of the important surgical tools that are required for handling, grasping, clamping and manipulating purposes mainly. They are many types of tweezers that look alike but are totally made for different operations.

The concept of gene transfer between cells first existed in bacteria; they are capable of at least four natural forms of genetic exchange. The genetic transfer technique is used very widely in basic research and applied biology. The delivery of DNA into an animal cell is a very established and fundamental procedure. It has become a very crucial tool for gene cloning, the study of gene function and the regulation and production of small amounts of recombinant proteins for analysis and verification. It helps to express the introduced genetic construct in the recipient cells or inactivate particular endogenous genes.

MICRO-ePORE is an advanced tool that ensures a much better success rate in the Genetic Transfer process. It works as DNA Microinjection and DNA is inserted into animal cells using microinjection.