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The synthesis of structurally complex organic molecules is the first task in the discovery of functional compounds needed for new technologies, including those in medicine and flexible electronics. Starting with relatively simple, purchasable reactants, the process involves sequences of chemical reactions in which the complexity of the molecules produced gradually increases with each step towards the final target. The sequences can be linear, or convergent (different parts of the target molecule are made in separate sequences and then joined together). To ensure that large amounts of the final product are prepared, each synthetic step must be high-yielding and reproducible, and must generate few side products.

"Global history faces two seemingly opposite challenges for an inter-dependent, over-heating planet. If we are going to muster meaningful narratives about the togetherness of strangers near and far, we are going to have to be more global and get more serious about engaging other languages and other ways of telling history. Historians and their reader-citizens are also going to have to re-signify the place of local attachments and meanings. Going deeper into the stories of Others afar and Strangers at home means dispensing with the idea that global integration was like an electric circuit, bringing light to the connected. Becoming inter-dependent is not just messier than drawing a wiring diagram. It means reckoning with dimensions of networks and circuits that global historians - and possibly all narratives of cosmopolitan convergence - leave out of the story: lighting up corners of the earth leaves others in the dark.  The story of the globalists illuminates some at the expense of others, the left behind, the ones who cannot move, and those who become immobilised because the light no longer shines on them."

"It's tempting to look at the recession as the cause of all this, the Great Fuckening from which we are still waiting to recover. But what we are living through now, and what the recession merely accelerated, is a historic convergence of economic maladies, many of them decades in the making. Decision by decision, the economy has turned into a young people-screwing machine. And unless something changes, our calamity is going to become America's."

Converging lines of evidence indicate that SARS-CoV-2, the coronavirus responsible for the COVID-19 pandemic, can pass from person to person in tiny droplets called aerosols that waft through the air and accumulate over time. After months of debate about whether people can transmit the virus through exhaled air, there is growing concern among scientists about this transmission route.