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Chris is expanding this article into a book, due out in May 2006. Follow his continuing coverage of the subject on The Long Tail blog. In 1988, a British mountain climber named Joe Simpson wrote a book called Touching the Void, a harrowing account of near death in the Peruvian Andes.

Dans cette conférence enregistrée par ForaTV en 2006, Chris Anderson présent son concept de longue traîne ("long tail" en anglais).

"La longue traîne [...] est une théorie qui décrit cette structure particulière du marché à l'ère d'internet, dans un grand nombre de secteurs. Le modèle économique ne repose plus sur une offre limitée d'articles produits à grande échelle, mais sur une offre très variée d'articles produits à peu d'exemplaires."

With this, we now know the exact mRNA contents of the BNT162b2 vaccine, and for most parts we understand why they are there: The CAP to make sure the RNA looks like regular mRNA A known successful and optimized 5' untranslated region (UTR) A codon optimized signal peptide to send the Spike protein to the right place (copied 100% from the original virus) A codon optimized version of the original spike, with two 'Proline' substitutions to make sure the protein appears in the right form A known successful and optimized 3' untranslated region A slightly mysterious poly-A tail with an unexplained 'linker' in there The codon optimization adds a lot of G and C to the mRNA. Meanwhile, using Ψ (1-methyl-3'-pseudouridylyl) instead of U helps evade our immune system, so the mRNA stays around long enough so we can actually help train the immune system.