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Rhett Ferrin

PBS: New Heroes: Dr.V and David Green - Eye Surgery India 02/02 - Desi Video Network - 0 views

www.desivideonetwork.com/...-green-eye-surgery-india-02-02

capitalism free market economics eye care dr. v

shared by Rhett Ferrin on 28 Sep 10 - No Cached
    • Rhett Ferrin
      Rhett Ferrin on 28 Sep 10
       
      I really like this story and the concept of sustainable business. Check out my blog for more imrhettferrin.blogspot.com
Brian Earley

Life's Lessons Learned - 0 views

new.lds.org/...lifes-lessons-learned

digiciv thoreau

shared by Brian Earley on 12 Oct 10 - No Cached
    • Brian Earley
      Brian Earley on 12 Oct 10
       
      Thoreau put his priorities on understanding himself.  We must make our priorities and work diligently for them.
  • I have known many great men and women.
  • they all have this in common: they work diligently and persistently towards achieving their goals
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  • “If one advances confidently in the direction of his dreams,” wrote Henry David Thoreau, “and endeavors to live the life which he has imagined, he will meet with a success unexpected in common hours.”1     UAdd a Note In other words, never take your eye off the ball.
  • Brian Earley on 12 Oct 10
     
    I love this football story, but it emphasizes following simple principles in a complex system.  "Keep your eye on the . . ." We each decide what fills the blank.  Let's see our dreams and advance confidently in that direction.
anonymous

Home | UTOPIA - 2 views

www.utopianet.org

open internet UTOPIA

shared by anonymous on 16 Aug 12 - No Cached
  • anonymous on 16 Aug 12
     
    This is an interesting idea. Essentially it is an open fiber network that internet service providers have the option of providing service on. It is sparking lots of debate due to is Private/Public funding. It is something that I would like to keep my eye on.
Erin Hamson

MIT OpenCourseWare | Biology | 7.012 Introduction to Biology, Fall 2004 | Video Lecture... - 0 views

ocw.mit.edu/...embed32

evolution mit science

shared by Erin Hamson on 18 Oct 10 - No Cached
  • And what this means is that if you look at a pedigree like this, and for example, here we have a mother and a father, girls are always round, boys are square. And here you'll see the mitochondrial DNA, it's donated to all of the children, but the fact is that these boys, when they mate, when they have offspring, they will no longer pass along her mitochondrial DNA, so it will be lost. And the only way the mitochondrial DNA can be transmitted is through one of her daughters, who in turn, have daughters.
  • Here's some other interesting principles. Mitochondrial DNA passes always from the mother, so when a fertilized egg is formed, Dad gives his chromosomes, but he doesn't donate for any, doesn't donate any mitochondrial DNA.
  • animals are related to one another. This is kind of a fun undertaking. Look at this. Why is it fun? Well it's, it's kind of an amusing idea, how often were cows domesticated during the history of humanity? How often were sheep domesticated? Pigs, water buffalos, and horses. And what you see here is that cattle were domesticated on two occasions, probably once in Western Asia, the middle east, and once in Eastern Asia. Sheep were domesticated twice, all modern sheep following these two families here
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  • And that is, certain genes can evolve progressively over a long period of time, because they don't encode vital functions, or they may even be sequences between genes that don't encode phenotype at all. Imagine, for example, we have a situation were here we have a gene which encodes a vital function, like the eye, here's another gene that encodes another function, oh I don't know, a leg. And here we have intergenic sequences. After all, as you have learned by now, more than 96% of the DNA in our genome, doesn't encode proteins, and probably isn't even responsible for regulating genes. So these sequences, right in here, can mutate freely during the course of evolution, without having a deleterious effect on the phenotype of the organism. There's no evolutionary pressure to constrain the evolution of these genes
  • And many of these neutral mutations, which have no effect on organismic fitness, but are simply evolutionary neutral, are sometimes called polymorphisms. The term polymorphism, -morph is once again morphology, derives from the fact that species tend to be polymorphic, we don't all have blond hair, we don't all have brown eyes.
  • If you look at two chimpanzees living on opposite sides of the same hill in West Africa, they are genetically far more distantly related to one another, than any one of us, by a factor of 10 to 15. Two chimpanzees, they look exactly the same, they have the same peculiar habits, but they're genetically far more distantly-related than we are to one-another, than I am to any one of you, or than any one of you is to one another. And what does that mean? It means that, roughly speaking, the species of chimpanzees is, at least, 10 or 15 times older than our species are. We're a young species, chimpanzees probably first speciated three or four million years ago, if the paleontological record is, is accurate. Paleontology is the study of old, dusty bones, so you can begin to imagine when chimpanzee bones become recognizable in the earth.
  • And what you see already, in such small populations, is that for example, this male here has two girls, and right away, to the extent he had an interesting Y chromosome, that Y chromosome was lost from the gene pool. This girl, here, had an interesting mitochondrial DNA, but right away that's lost, because she has, she has just two boys. And what you see, in very rapid order, in small populations, there's a homogenization of the genetic compliment, just because the alleles are lost within what's called, genetic drif
  • And if you ask that question, the answer is that we all had a common ancestress who lived about 150,000 years ago. All of us trace our mitochondrial DNA to her. Does that mean that there was only one woman alive there, she's called, Mitochondrial-Eve, again, we don't know her name. Does that mean there was only one woman alive, well it doesn't mean that at all because of what I just told you, in small populations the proto-human population.
  • How much are all of our mitochondrial DNA are related to one another, how distantly related are they to one another, given the rate of evolution of mitochondrial DNA sequences?
  • So where do we all come from, all of us human beings? How closely related are we to one another? Here's, here's a measurement of the distances between different mitochondrial DNA's from different branches of humanity. And what you see is something really quite extraordinary and stunning. Here, you'll see that the people, the non-African lineages here and here, are actually relatively closely related to one another.
  • And by the way, all the genes that are present here, the alleles that are present here, can also be found in Africa, but in relatively small proportions in Africa
    • Erin Hamson
      Erin Hamson on 18 Oct 10
       
      Suggesting that all people came from Africa
  • So, what happens there, that's a testimonial to the tragic fate of the Indians, where the conquistadors from Spain came in, killed all the men, and took all the women, to be their brides. How else can you explain the fact that there's no Indian Y chromosomes, there's all, there is instead only European Y chromosomes.
  • When you do genetic counseling of family these days, one of the strictures is, that you never tell the family if the children have genetic polymorphisms that don't match that of the person whom they think is their father. They don't look like their, the person whom they regard as father, but that's always assumed to be a role of the genetic dice.
  • Here's a fun story I like to tell each year, and it's about the Cohen and Y chromosome, and you'll see what an amusing story this is, just from genetics. Now the name Cohen, in Hebrew means, a high priest, and you've heard people named Cohen, it's not such an uncommon name among the Jews. And it says, in the Bible, in Genesis and Exodus, that all the high priests in the Bible are the descendants of Aaron, the brother of Moses.
  • hen it should be the case that all male Cohen's should have the same Y chromosome, right?
  • Because keep in mind, any single affair with the milkman or the mailman, over 3,000 years, would've broke this chain of inheritance, any single incidence of non-paternity. It's a really astounding story, and it's hard, there can be no artifact to it, there's no bias in it, there's no other way to explain it.
  • And what they found was that all members of the, almost all members of the ruling cast among the Lembas, had the same Y chromosome, and the Y chromosome had exactly the same polymorphisms of the Cohen Y chromosome
  • What I'm telling you is that these two genes are totally interchangeable, that they are effectively indistinguishable from one another, functionally they have some sequence relatedness, but in terms of the way they program development, they are effectively equivalent. And what this means is that the progenitor of these two genes must've already existed at the time that the flies and we diverged, which six or seven-hundred million years ago, and in the intervening six or seven-hundred million years, these genes have been totally unchanged.
  • once the gene was developed, evolution could not tinker with it, and begin to change it in different ways, ostensibly because such tinkering would render these genes dysfunctional, and thereby would inactivate them, thereby depriving the organism of a critical sensory organ.
  • Erin Hamson on 18 Oct 10
     
    An excellent discourse on who evolution works, and what it means for us today.
Gideon Burton

I'm So Totally, Digitally Close to You - Clive Thompson - NYTimes.com - 0 views

www.nytimes.com/...07awareness-t.html

social media friendship relationships Facebook nytimes weak ties

shared by Gideon Burton on 05 Sep 12 - Cached
  • Social scientists have a name for this sort of incessant online contact. They call it “ambient awareness.” It is, they say, very much like being physically near someone and picking up on his mood through the little things he does — body language, sighs, stray comments — out of the corner of your eye
  • This is the paradox of ambient awareness. Each little update — each individual bit of social information — is insignificant on its own, even supremely mundane. But taken together, over time, the little snippets coalesce into a surprisingly sophisticated portrait of your friends’ and family members’ lives, like thousands of dots making a pointillist painting
  • Gideon Burton on 05 Sep 12
     
    A 2008 article in which the new kinds of digital relationships made possible through Facebook and other social media are discussed. Digital friends have "ambient awareness" through news feeds, begging the question about kind of friendship and their authenticity.
Gideon Burton

Dear Internet: It's No Longer OK to Not Know How Congress Works - 1 views

www.informationdiet.com/...o-not-know-how-congress-works-

congress government sopa politics

shared by Gideon Burton on 07 Jan 12 - No Cached
  • the federal government is not attached to Moore's Law
  • Here's an area for both some disruption and some lobbying. Let's build tools that allow members of Congress to aggregate messages being sent to them, and to associate those messages with congressional districts. Let's come up with a way for a member to see what their constituency is saying about any particular issue they'd like, and let's provide that as an open service so that anybody can see what a particular constituency is saying. That way, when a member has a track record of voting against the desires of a substantial portion of his or her district, we've got a record of it, and it can get brought up in the next election.
  • Right now, your voice online -- in the mediums you participate in, not only don't matter: legally they can't matter. Online identities don't count when it comes to the official record
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  • The skill of making software isn't just about making cool software. It's about rewiring society. The sooner we acknowledge that, the sooner we can get on with the rewiring, and hopefully with a watchful eye, rewire it for the better.
  • Gideon Burton on 07 Jan 12
     
    Very important article on those in the info culture needing to understand and speak the language of Congress in order to properly educate and influence it on internet related matters.
Greg Williams

Many Eyes - 0 views

www-958.ibm.com/...manyeyes

visualization data DataVisualization infographics

shared by Greg Williams on 19 Sep 12 - No Cached
  • Greg Williams on 19 Sep 12
     
    data visualization site
Katherine Chipman

Margaret Cavendish: Observations Upon Experimental Philosophy - 0 views

burton.byu.edu/...cavendish.htm

margaret cavendish

shared by Katherine Chipman on 21 Sep 10 - No Cached
  • In short, Magnifying-glasses are like a high heel to a short legg, which if it be made too high, it is apt to make the wearer fall, and at the best, can do no more then represent exterior figures in a bigger, and so in a more deformed shape and posture then naturally they are; but as for the interior form and motions of a Creature, as I said before, they can no more represent them, then Telescopes can the interior essence and nature of the Sun, and what matter it consists of; for if one that never had seen Milk before, should look upon it through a Microscope, he would never be able to discover the interior parts of Milk by that instrument, were it the best that is in the World; neither the Whey, nor the Butter, nor the Curds. Wherefore the best optick is a perfect natural Eye, and a regular sensitive perception, and the best judg is Reason, and the best study is Rational Contemplation joyned with the observations of regular sense, but not deluding Arts
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