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As the U.S. Food and Drug Administration (FDA) considers approving a genetically modified (GM) Atlantic salmon (Salmo salar), it faces fundamental questions of risk analysis and impact assessment. The GM salmon-whose genome contains an inserted growth gene from Pacific chinook salmon (Oncorhynchus tshawytscha) and a switch-on gene from ocean pout (Zoarces americanus)-would be the first transgenic animal approved for human consumption in the United States (1, 2). But the mechanism for its approval, FDA's new animal drug application (NADA) process (2), narrowly examines only the risks of each GM salmon compared with a non-GM salmon (2, 3). This approach fails to acknowledge that the new product's attributes may affect total production and consumption of salmon. This potentially excludes major human health and environmental impacts, both benefits and risks. Regulators need to consider the full scope of such impacts in risk analyses to avoid unintended consequences (4), yet FDA does not consider ancillary benefits and risks from salmon market expansion (2, 3), a result of what may be an overly narrow interpretation of statutes.

"Science 25 November 2011: Vol. 334 no. 6059 p. 1040 DOI: 10.1126/science.334.6059.1040 * News & Analysis Climate Change Humans Are Driving Extreme Weather; Time to Prepare 1. Richard A. Kerr Figure View larger version: * In this page * In a new window Thai floods 2011 Hurricane Katrina 2005 Texas drought 2011 "CREDITS (LEFT TO RIGHT): PAULA BRONSTEIN/GETTY IMAGES; JEFF SCHMALTZ, MODIS RAPID RESPONSE TEAM, NASA/GSFC; NOAA" An international scientific assessment finds for the first time that human activity has indeed driven not just global warming but also increases in some extreme weather and climate events around the world in recent decades. And those and likely other weather extremes will worsen in coming decades as greenhouse gases mount, the report finds. But uncertainties are rife in the still-emerging field of extreme events. Scientists cannot attribute a particular drought or flood to global warming, and they can say little about past or future trends in the risk of high-profile hazards such as tropical cyclones. Damage from weather disasters has been climbing, but the report can attribute that trend only to the increasing exposure of life and property to weather risks. Climate change may be involved, but a case cannot yet be made. Despite the uncertainties, the special report from the Intergovernmental Panel on Climate Change (IPCC) released 18 November stresses that there is still reason for taking action now. The panel recommends "low-regrets measures," such as improvements in everything from drainage systems to early warning systems. Such measures would benefit society in dealing with the current climate as well as with almost any range of possible future climates. The report takes a cautious, consensus-based approach that draws on the published literature. Headlines and even some scientists may point to the current Texas drought or the 2003 European heat wave as the result of the strengthening greenhouse. But the report fin

"Oil Exploration Oil Exploration Gulf Drilling Disaster Triggers Scrutiny of Mediterranean Oil Rush 1. Laura Margottini* A rush to find and extract oil in the Mediterranean Sea is threatening one of the planet's marine biodiversity hot spots, scientists warn. PANTELLERIA, ITALY-This tiny speck in the Mediterranean, home to a few thousand people, seems like one of the most tranquil places in the world. But looks are deceptive. Pantelleria, in the Strait of Sicily halfway between Palermo and Tunis, is close to one of the world's busiest shipping lanes, and of late, its waters have also become the center of a new oil rush. Attracted by Italy's easygoing drilling regulations and low tax on oil extraction, dozens of companies have new plans for exploration and drilling in this part of the Mediterranean Sea. At a recent meeting here,* however, scientists, conservationists, and environmental activists warned that such efforts put several important biodiversity hot spots in danger. An oil disaster like the Deepwater Horizon explosion, which sent oil gushing into the Gulf of Mexico for months, could easily ruin the Mediterranean ecology for a century or longer, some said. The Italian government has recently issued 66 permissions for drilling around its coasts and 25 concessions for exploration. Another 67 applications for exploration are under review. "Italy now represents the region that holds the most exciting and significant long-term opportunities," one company, Northern Petroleum, says on its Web site. The Strait of Sicily is the center of attention, but other biodiversity hot spots, such as the Tremiti Islands in the Adriatic Sea, could soon be explored as well. Italy isn't alone. Tunisia, for example, has granted concessions for oil exploration for most of its Mediterranean waters, without much political opposition. But the areas coveted by oil companies are ecological treasures, researchers and groups such as Greenpeace Italy stress. Last year, the Uni

"Some of the planet's most beautiful and diverse ecosystems are at risk. With temperatures on the rise, coral reefs are at greater risk for coral bleaching. Using ocean observing system data from NOAA's National Data Buoy Center, this classroom activity examines ocean temperatures off Puerto Rico to see how coral reefs are being impacted and predict what's on the horizon. Brought to you by Sea Grant's Bridge website and COSEE-NOW. This activity was developed in response to the 2005 massive coral bleaching event in the Caribbean caused by high sea surface temperatures. Using ocean observing system data, water temperatures can be monitored to evaluate the likeliness of other bleaching events. Via the COSEE-NOW online community, we were able to receive valuable feedback on making the graph of water temperature more user-friendly and expanding the discussion questions to evoke some higher level thinking from students. This activity has been demonstrated to teachers at the National Marine Educators Association conference and Virginia Sea Grant professional development institutes; and to graduate students in several different settings. http://www2.vims.edu/bridge/DATA.cfm?Bridge_Location=archive0406.html"

"In some cases, cheaper types of fish were substituted for expensive species. In others, fish that consumers have been urged to avoid because stocks are depleted, putting the species or a fishery at risk, was identified as a type of fish that is not threatened. Although such mislabeling violates laws protecting consumers, it is hard to detect. Some of the findings present public health concerns. Thirteen types of fish, including tilapia and tilefish, were falsely identified as red snapper. Tilefish contains such high mercury levels that the federal Food and Drug Administration advises women who are pregnant or nursing and young children not to eat it."

"Science 25 November 2011: Vol. 334 no. 6059 pp. 1052-1053 DOI: 10.1126/science.334.6059.1052 * News Focus Adaptation to Climate Change Adaptation to Climate Change Time to Adapt to a Warming World, But Where's the Science? 1. Richard A. Kerr With dangerous global warming seemingly inevitable, users of climate information-from water utilities to international aid workers-are turning to climate scientists for guidance. But usable knowledge is in short supply. Figure View larger version: * In this page * In a new window Adapt to that. Climate will change, but decision-makers want to know how, where, and when. "CREDIT: KOOS VAN DER LENDE/NEWSCOM" DENVER, COLORADO-The people who brought us the bad news about climate change are making an effort to help us figure out what to do about it. As climate scientists have shown, continuing to spew greenhouse gases into the atmosphere will surely bring sweeping changes to the world-changes that humans will find it difficult or impossible to adapt to. But beyond general warnings, there is another sort of vital climate research to be done, speakers told 1800 attendees at a meeting here last month. And so far, they warned, researchers have delivered precious little of the essential new science. At the meeting, subtitled "Climate Research in Service to Society,"* the new buzzword was "actionable": actionable science, actionable information, actionable knowledge. "There's an urgent need for actionable climate information based on sound science," said Ghassem Asrar, director of the World Climate Research Programme, the meeting's organizer based in Geneva, Switzerland. What's needed is not simply data but processed information that an engineer sizing a storm-water pipe to serve for the next 50 years or a farmer in Uganda considering irrigating his fields can use to make better decisions in a warming world. Researchers preparing for the next international climate assessment, due in 2013, delive

Information Science Bounds and Vision Atlas of Science Visualizing What We Know by Katy Börner MIT Press, Cambridge, MA, 2010. 266 pp. $$29.95, £22.95. ISBN 9780262014458. 1. Mason A. Porter + Author Affiliations 1. The reviewer is at the Oxford Centre for Industrial and Applied Mathematics, Mathematical Institute, University of Oxford, Oxford OX1 3LB, UK, and at the CABDyN Complexity Centre and Somerville College, University of Oxford. 1. E-mail: porterm@maths.ox.ac.uk Visualization is a crucial but underappreciated part of science. As venues like the American Physical Society's Gallery of Fluid Motion and Gallery of Nonlinear Images illustrate every year, good visuals can make science more beautiful, more artistic, more tangible, and often more discernible. Katy Börner's continuing exhibition Places & Spaces: Mapping Science (1) and her book Atlas of Science: Visualizing What We Know arise from a similar spirit but are much more ambitious. Visualization is one of the most compelling aspects of science. Breathtaking visuals from sources like fractals and Disneyland's long-dead "Adventure Thru Inner Space" ride are what originally inspired me toward my personal scientific path, so I welcome any resource that promises to bring the visual joys of discovery to a wide audience. Importantly, Börner's exhibition and book are not mere artistic manifestations, although they would be impressive accomplishments even if that were her only goal. Some scientists have occasionally had great success in the visual arts; for example, physicist Eric Heller has long exhibited the gorgeous fruits of his research on quantum chaos and other topics (2). To fully appreciate Börner's efforts, however, one must be conscious that she is deeply concerned not just with visualization itself but with the science of visualization. Accordingly, her book discusses the history of the science of visualization, where it is now, and where she thinks it can go. Atlas of Scie