Cerebral Palsy

NICHD Center for Developmental Biology & Perinatal Medicine (CDBPM). The CDBPM supports scientists who are advancing fundamental and clinical knowledge about maternal health and problems of child development, including preterm labor and birth, intellectual and developmental disabilities, congenital and genetic disorders, fetal growth restriction, and other conditions. The Center and its programs aim to maximize human development, prevent diseases and disorders, and improve diagnoses, therapy, and clinical care.

NICHD program focuses on developing research that links PCCR medicine and science to the epidemiology, prevention, and treatment of childhood disabilities. The effort sponsors competitive research on all aspects of PCCR-including critical analyses of outcomes for children who are survivors of trauma, congenital anomalies, neonatal asphyxia, infectious processes, septic shock, and many other less common, but still devastating hildhood processes. The PCCR program also provides support for the Pediatric Critical Care Scientist Development Program (PCCSDP) , a national faculty training and career development program that develops successful pediatric critical care physician scientists conducting research to enhance the scientific understanding, clinical management, and rehabilitation of pediatric critical illness.

Ongoing clinical trial sponsored by the University of Texas Southwestern Medical Center to Evaluate the Effects of a Single Dose of Intravenous Premarin for the Treatment of Severe Traumatic Brain Injury

Completed study sponsored by National Institutes of Health Clinical Center CC to identify clinical signs and symptoms critical for diagnosing swallowing disorders and will characterize swallowing problems in various patient populations, such as patients with Parkinson's disease, stroke, post-polio syndrome, multiple sclerosis and other conditions that cause swallowing abnormalities.

Completed study sponsored by Fortaleza Univerity with the purpose of describing functional endoscopic evaluation of swallowing findings in children with cerebral palsy.

Completed study examined tongue strength and endurance, how the tongue applies pressure during swallowing, and how the chin muscles react during swallowing in healthy volunteers and in patients with dysphagia (difficulty swallowing). The information from this study may be helpful in developing better treatments for people with swallowing problems

Ongoing study sponsored by the University of Utah to determine the percentage of patients presenting with dysphagia who are found to have eosinophilic esophagitis (EoE) and to establish which presenting factors warrant esophageal biopsies.

Completed study sponsored by NINDS to determine the feasibility of using extrinsic laryngeal muscle stimulation to elevate the larynx in a manner similar to that which occurs during normal swallowing. This research will also determine whether laryngeal elevation will open the upper esophageal sphincter to assist with entry of the bolus into the esophagus. Includes studies in normal volunteers and patients with swallowing disorders.

Ongoing study sponsored by the University of Texas Health Science Center, Houston to evaluate the efficacy of fundoplication in premature infants with GERD and BPD.

The purpose of this study is to provide additional information on safety and tolerability after multiple does of pantoprazole in infants

Multicenter, randomized, controlled trial to compare the anti-seizure effect of parenteral MgSO4 versus oral labetalol in hypertensive pregnant women who are eligible for MgSO4 therapy. The primary outcome measure is eclampsia, and the secondary outcome measures include blood pressure control, and relevant antenatal, intrapartum, and postnatal maternal and fetal/neonatal parameters including adverse effects and complications.

This study is an observational study to prove that a new device, which measures the force of delivering a baby, (US patent 6,684,165) functions as described in the patent. This is the first time this has been used with patients. The device measures the force (pounds/kilograms) that is exerted as a doctor/midwife pulls on a baby during the delivery

Data involving orthopaedic conditions and rehabilitation aspects of musculoskeletal and neuromuscular disorders will be collected and stored as part of the normal clinical care of patients seen in the University of Florida (UF) and Shands Orthopaedics and Sports Medicine Institute.

United Kingdom study investigating new ways to stretch knee contractures in children with cerebral palsy using a specially designed splint.

The Agency for Healthcare Research and Quality (AHRQ) is the health services research arm of the U.S. Department of Health and Human Services (HHS), complementing the biomedical research mission of its sister agency, the National Institutes of Health. AHRQ is a home to research centers that specialize in major areas of health care research such as quality improvement and patient safety, outcomes and effectiveness of care, clinical practice and technology assessment, and health care organization and delivery systems. Source of funding and technical assistance for health services research and research training at leading U.S. universities and other institutions, as well as a science partner, working with the public and private sectors to build the knowledge base for what works-and does not work-in health and health care and to translate this knowledge into everyday practice and policymaking.

As the lead Federal agency charged with supporting and conducting health services research, the Agency for Health Care Policy and Research (AHCPR) has undertaken and funded important studies in many areas of long-term care research. The bibliographies tlisted provide citations for selected findings as well as a complete listing of long-term care research conducted and funded by AHCPR since 1990

The Agency for Healthcare Research and Quality (AHRQ) sponsored preparation of this atlas to support local/regional planning and response efforts in the event of a bioterrorism or other public health emergency. In the atlas, case studies in six areas illustrate the location of nursing homes relative to population and various emergency preparedness regions. There are also maps of the location of hospitals and nursing homes in all 50 States and the District of Columbia. Atlas and Downloadable Information available

The Public Access Policy ensures that the public has access to the published results of NIH funded research to help advance science and improve human health. It requires scientists to submit final peer-reviewed journal manuscripts that arise from NIH funds to the digital archive PubMed Central upon acceptance for publication

A service of the U.S. National Library of Medicine and the National Institutes of Health. MedlinePlus will direct you to information to help answer health questions. MedlinePlus brings together authoritative information from NLM, the National Institutes of Health (NIH), and other government agencies and health-related organizations. Preformulated MEDLINE searches are included in MedlinePlus and give easy access to medical journal articles. MedlinePlus also has extensive information about drugs, an illustrated medical encyclopedia, interactive patient tutorials, and latest health news.

Study sponsored by the university of Chicago to demonstrate the efficacy and safety of Vanquix for the management of acute repetitive seizures (ARS). Study will provide clinical evidence for the effective and safe use of a diazepam auto-injector, Vanquix, to provide patients and their caregivers with an alternative to rectal administration.