PubMed Abstract - Sensory and motor deficits in children with cerebral palsy born preterm correlate with diffusion tensor imagine abnormalities in thalamocortical pathways. Cerebral palsy (CP) is frequently linked to white matter injury in children born preterm. Diffusion tensor imaging (DTI) is a powerful technique providing precise identification of white matter microstructure. We investigated the relationship between DTI-observed thalamocortical (posterior thalamic radiation) injury, motor (corticospinal tract) injury, and sensorimotor function.
National Library of Medicine - National Institute of Health - PubMed Abstract - Brain magnetic resonance imagine in suspected extrapyramidal cerebral palsy; observations in distinguishing genetic-metabolic from acquired causes
National Library of Medicine - National Institute of Health PubMed Abstract - Extrapyramidal cerebral palsy: a changing view - Earlier surveys of cerebal palsy characterized patients with extrapyramidal (choreoathetoid) cerebral palsy as having little cognitive impairment and few associated deficits. Anoxia, which has now replaced neonatal hyperbilirubinemia as a major cause of this type of cerebral palsy, predictably produces a diffuse type of brain damage.
PubMed Study Abstract: Growth and health in children with moderate-to-severe cerebral palsy. Study proposed to describe observed growth patterns and their relationship to health and social paricipation in a respresentative sample of children with moderate-to-severe cerebral palsy.
PubMed Abstract of study to determine the association of hypotonia and depression in neonates at or near term with metabolic acidemia at birth (umbilical arterial pH<-12 mM).
PubMed Abstract of study is to verify whether neurophysiological and communicative-relational aspects in hypotonic subjects can be recovered by psychomotor therapy.
National Library of Medicine National Institutes of Health PubMed Abstract: Antenatal magnesium sulfate for the prevention of cerebral palsy in preterm infants less than 34 weeks gestation: a systematic reiew and metaanalysis
PubMed Abstract of study to determine whether hyperoxaemia and/or hypocapnia during the first 2 hours of
life add to the risk of brain injury after intrapartum asphyxia"
PubMed Study Abstract: Vasoparalysis associated with brain damage in asphyxiated term infants - Dept of Neonatalogy, Rigshospitalet, Copenhagaon, Denmark, 1990
Long-term evaluation of granulocyte-colony stimulating factor on hypoxic-ischemic brain damage in infant rats. Hypoxia-ischemia (HI), as a major cause of fetal brain damage, has long-lasting neurological implications. Therefore, therapeutic interventions that attenuate
the neuropathological out come of HI while also improving the neurofunctional outcome are of paramount clinical importance. The aim of this study was to investigate the long-term functional and protective actions of granulocyte-colony stimulating factor (G-CSF) treatment in an experimental model of cerebral. RESULTS: Granulocyte-colony stimulation promoted somatic growth and prevented brain atrophy and underdevelopment of the heart in infant rats.
PubMed Study Abstract - Dept. of Pediatrics, Tokyo Medical and Dental University, Japan study of clinical and neuropathological findings in severe athetoid cerebral palsy: a comparative study of globo-Luysian and thalamo-putaminal groups.
PubMed Abstract of study that concluded that passive stretching of spastic hamstrings in the hip flexion position resulted in Dynamic Posterior Displacement of the Femoral Head. Medical professionals should be aware of this fact, especially in Spastic Ccerebral Palsy children with a higher migration percentage on radiograph.
PubMed Abstract: Study - Although the frequent occurrence of Scoliosis in patients who have Spastic Cerebral Palsy is well known and surgical treatment has often been recommended for these patients, little is known about the natural history of scoliosis in this population. This study objection was to clarify the natural history of scoliosis from childhood through to adulthood and provide objective data on proper surgical indications for such patients.
PubMed Abstract of Characteristics of Childen with hip displacement in cerebral palsy. Study concluded that hip displacement in CP often occurs already at 2-3 years of age. Range of motion is a poor indicator of hips at risk. Thus early identification and early radiographic examination of children at risk is of great importance. The risk of hip displacement varies according to both CP-subtype and GMFCS
PubMed Abstract of observations that concluded that significant improvements were noted when comparing the two-electrode system with the new multiple level electrode. Marked to moderately improved patients increased from 57 to 84% in Cerebral Palsy, from 44 to 82% in dystonia, from 53 to 75% in torticollis and from 53 to 80% in Cystonia, from 53 to 80% in posttraumatic neurologic conditions
PubMed Abstract of double-blind study of high cervical spinal cord stimulation conducted in eight moderately disabled, spastic, cerebral palsied children failed to demonstrate any significant improvement over base line function during chronic spinal cord stimulation at either optimal stimulation parameters or random placebo
parameters