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Lee Vander Loop

Heartburn, Gastroesophageal Reflux (GER), and Gastroesophageal Reflux Disease (GERD) - 0 views

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    National Digestive Diseases Information Clearinghouse (NDDIC) A service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH Heartburn, Gastroestophageal Reflux Disease (GERD)
Lee Vander Loop

To Evaluate the Safety and Efficacy of Rabeprazole in Infants With Gastroesophageal Ero... - 0 views

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    Purpose of this study is to assess the effectiveness and safety of rabeprazole sodium, an inhibitor of gastric acid secretion of the protein pump inhibitor (PPI) class, compared with placebo in the treatment of gastrointestinal esophageal reflux disease (GERD) in infants 1 to 11 months of age.
Lee Vander Loop

Medical Treatment for Gastroesophageal Reflux Disease (GERD) in Preterm Infants - 0 views

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    Study Question: In premature infants with apnea and/or bradycardia attributed to gastroesophageal reflux disease (GERD), does treatment with medications (acid blockers and motility agents), compared to placebo, reduce the frequency of apnea and bradycardia?"
Lee Vander Loop

Pharmacokinetics of Immediate-Release vs. Delayed-Release Omeprazole in Gastroparesis - 0 views

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    Completed study comparing the blood drug levels of two prescribed medications, Immediate-release omeprazole 40 mg powder and delayed-release omeprazole 40 mg capsule to determine which drug is better absorbed in patients with a slow stomach emptying (gastroparesis). Delayed-release omeprazole has a protective coating to prevent the drug omeprazole from being neutralized by stomach acid. Immediate-release omeprazole has sodium bicarbonate (antacid) which neutralizes the stomach acid, eliminating the need for a protective coating. Immediate-release omeprazole suspension may have a more rapid pharmacokinetic profile and greater overall drug absorption in gastroparesis.
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