Best content in Cancer | Diigo

Green tea may negate the effects of a common cancer therapy - 0 views

Matti Narkia on 26 Feb 09

(WASHINGTON, February 3, 2009) - Green tea products have become regarded as a valuable health supplement, as studies have shown evidence of its benefit against a variety of diseases, including cancer. However, a new study suggests that some components of green tea may counteract the anticancer effects of one cancer therapy, bortezomib (Velcade®), and may be contraindicated for patients taking this medicine to ensure its maximum therapeutic benefit. This study is being prepublished online today in Blood, the official journal of the American Society of Hematology.

<div class="cArrow"> </div><div class="cContentInner">(WASHINGTON, February 3, 2009) - Green tea products have become regarded as a valuable health supplement, as studies have shown evidence of its benefit against a variety of diseases, including cancer. However, a new study suggests that some components of green tea may counteract the anticancer effects of one cancer therapy, bortezomib (Velcade®), and may be contraindicated for patients taking this medicine to ensure its maximum therapeutic benefit. This study is being prepublished online today in Blood, the official journal of the American Society of Hematology.</div>

...

Cancel

Older Men Urged to Consider a Drug to Prevent Prostate Cancer - NYTimes.com - 0 views

Matti Narkia on 26 Feb 09

For the first time, medical groups have issued guidelines that say healthy older men should consider taking a drug that may reduce their risk of developing prostate cancer, even if they're just among the worried well who go in for regular screenings.\n\nThe drug, finasteride, is already used to treat male pattern baldness and to shrink enlarged prostates. The new guidelines suggest that patients who are already taking finasteride for those conditions or who go for regular prostate cancer screening tests should discuss long-term treatment with the drug with their doctors.

<div class="cArrow"> </div><div class="cContentInner">For the first time, medical groups have issued guidelines that say healthy older men should consider taking a drug that may reduce their risk of developing prostate cancer, even if they're just among the worried well who go in for regular screenings.\n\nThe drug, finasteride, is already used to treat male pattern baldness and to shrink enlarged prostates. The new guidelines suggest that patients who are already taking finasteride for those conditions or who go for regular prostate cancer screening tests should discuss long-term treatment with the drug with their doctors.</div>

...

Cancel

Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective -... - 0 views

Matti Narkia on 26 Feb 09

Welcome to dietandcancerreport.org where you can find the WCRF/AICR Expert Report, Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective as well as the companion report, Policy and Action for Cancer Prevention. The most up to date reference and resource materials associated with both reports are available from this site

<div class="cArrow"> </div><div class="cContentInner">Welcome to dietandcancerreport.org where you can find the WCRF/AICR Expert Report, Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective as well as the companion report, Policy and Action for Cancer Prevention. The most up to date reference and resource materials associated with both reports are available from this site</div>

...

Cancel

AICR: Second Expert Report: Food, Nutrition, Physical Activity, and the Prevention of C... - 0 views

Matti Narkia on 26 Feb 09

Second Expert Report\n\nFood, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective\n\nIt began in 2001 with AICR and its international affiliate, WCRF-UK committing themselves to systematically review and analyze the total body of scientific evidence on the relationship of diet, physical activity and weight management to cancer risk. After a rigorous five-year process, Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective does just that.

<div class="cArrow"> </div><div class="cContentInner">Second Expert Report\n\nFood, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective\n\nIt began in 2001 with AICR and its international affiliate, WCRF-UK committing themselves to systematically review and analyze the total body of scientific evidence on the relationship of diet, physical activity and weight management to cancer risk. After a rigorous five-year process, Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective does just that.</div>

...

Cancel

AICR: Policy Report: Policy and Action for Cancer Prevention - 0 views

www.aicr.org/...PageServer

AICR: Policy Report WCRF Cancer Prevention Cancer_Prevention info portal directory action video viseos presentations

shared by Matti Narkia on 26 Feb 09 - Cached

Matti Narkia on 26 Feb 09

Policy Report\n\nLearn more about the new WCRF/AICR report, Policy and Action for Cancer Prevention, which was launched at an international press briefing in London at 10 a.m. GMT (5 a.m. US Eastern Time), and presented to US lawmakers at a Congressional Briefing at 10 a.m. US Eastern Time, on February 26th, 2009.

<div class="cArrow"> </div><div class="cContentInner">Policy Report\n\nLearn more about the new WCRF/AICR report, Policy and Action for Cancer Prevention, which was launched at an international press briefing in London at 10 a.m. GMT (5 a.m. US Eastern Time), and presented to US lawmakers at a Congressional Briefing at 10 a.m. US Eastern Time, on February 26th, 2009.</div>

...

Cancel

Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and h... - 0 views

Matti Narkia on 27 Feb 09

Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo.\nChen Q, Espey MG, Sun AY, Lee JH, Krishna MC, Shacter E, Choyke PL, Pooput C, Kirk KL, Buettner GR, Levine M.\nProc Natl Acad Sci U S A. 2007 May 22;104(21):8749-54. Epub 2007 May 14.\nPMID: 17502596 \n doi: 10.1073/pnas.0702854104\n

<div class="cArrow"> </div><div class="cContentInner">Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo.\nChen Q, Espey MG, Sun AY, Lee JH, Krishna MC, Shacter E, Choyke PL, Pooput C, Kirk KL, Buettner GR, Levine M.\nProc Natl Acad Sci U S A. 2007 May 22;104(21):8749-54. Epub 2007 May 14.\nPMID: 17502596 \n doi: 10.1073/pnas.0702854104\n</div>

...

Cancel

Phase I clinical trial of i.v. ascorbic acid in advanced malignancy. - Ann Oncol. 2008 ... - 0 views

Matti Narkia on 27 Feb 09

Phase I clinical trial of i.v. ascorbic acid in advanced malignancy. Hoffer LJ, Levine M, Assouline S, Melnychuk D, Padayatty SJ, Rosadiuk K, Rousseau C, Robitaille L, Miller WH Jr. Ann Oncol. 2008 Nov;19(11):1969-74. Epub 2008 Jun 9. Erratum in: Ann Oncol. 2008 Dec;19(12):2095. PMID: 18544557 doi:10.1093/annonc/mdn377

<div class="cArrow"> </div><div class="cContentInner">Phase I clinical trial of i.v. ascorbic acid in advanced malignancy. Hoffer LJ, Levine M, Assouline S, Melnychuk D, Padayatty SJ, Rosadiuk K, Rousseau C, Robitaille L, Miller WH Jr. Ann Oncol. 2008 Nov;19(11):1969-74. Epub 2008 Jun 9. Erratum in: Ann Oncol. 2008 Dec;19(12):2095. PMID: 18544557 doi:10.1093/annonc/mdn377 </div>

...

Cancel

Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive ... - 0 views

Matti Narkia on 27 Feb 09

Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice. Chen Q, Espey MG, Sun AY, Pooput C, Kirk KL, Krishna MC, Khosh DB, Drisko J, Levine M. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11105-9. Epub 2008 Aug 4. PMID: 18678913 doi: 10.1073/pnas.0804226105

<div class="cArrow"> </div><div class="cContentInner">Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice. Chen Q, Espey MG, Sun AY, Pooput C, Kirk KL, Krishna MC, Khosh DB, Drisko J, Levine M. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11105-9. Epub 2008 Aug 4. PMID: 18678913 doi: 10.1073/pnas.0804226105 </div>

...

Cancel

Vitamin C and cancer revisited - PNAS - 0 views

Matti Narkia on 27 Feb 09

Vitamin C and cancer revisited. Frei B, Lawson S. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11037-8. Epub 2008 Aug 5. PMID: 18682554

<div class="cArrow"> </div><div class="cContentInner">Vitamin C and cancer revisited. Frei B, Lawson S. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11037-8. Epub 2008 Aug 5. PMID: 18682554</div>

...

Cancel

Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a p... - 0 views

Matti Narkia on 27 Feb 09

Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues. Chen Q, Espey MG, Krishna MC, Mitchell JB, Corpe CP, Buettner GR, Shacter E, Levine M. Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13604-9. Epub 2005 Sep 12. PMID: 16157892

<div class="cArrow"> </div><div class="cContentInner">Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues. Chen Q, Espey MG, Krishna MC, Mitchell JB, Corpe CP, Buettner GR, Shacter E, Levine M. Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13604-9. Epub 2005 Sep 12. PMID: 16157892</div>

...

Cancel

Differential effects of selenium on benign and malignant prostate epithelial cells: sti... - 0 views

Matti Narkia on 27 Feb 09

Differential effects of selenium on benign and malignant prostate epithelial cells: stimulation of LNCaP cell growth by noncytotoxic, low selenite concentrations. Kandaş NO, Randolph C, Bosland MC. Nutr Cancer. 2009;61(2):251-64. PMID: 19235042

<div class="cArrow"> </div><div class="cContentInner">Differential effects of selenium on benign and malignant prostate epithelial cells: stimulation of LNCaP cell growth by noncytotoxic, low selenite concentrations. Kandaş NO, Randolph C, Bosland MC. Nutr Cancer. 2009;61(2):251-64. PMID: 19235042 </div>

...

Cancel

Vitamin D may inhibit prostate cancer growth - mechanism reported - 0 views

www.nutraingredients.com/...ng.asp

2006 february news prostate cancer prostate_cancer PCa vitamin_D vitamin D growth-inhibitory mechanism mechanisms

shared by Matti Narkia on 24 Feb 09 - Cached

Matti Narkia on 24 Feb 09

The in vitro study, reported in the journal Carcinogenesis (Vol. 27, pp. 32-42), showed that vitamin D, in the form of the highly active 1alpha, 25-dihydroxyvitamin D3 (1,25-VD), inhibited the function of protease enzymes that are involved in tumour invasion. "We found that 1,25-VD decreased matric metalloproteinases (MMP-9) and cathepsins (CPs), while it [also] increased the activity of their counterparts, tissue inhibitors of metalloproteinase-1 (TIMP-1) and cathepsin inhibitors," wrote lead author Bo-Ying Bao from the University of Rochester and Taipei Medical University. "Mechanistic studies showed that 1,25-VD did not suppress MMP-9 expression at the transcriptional level, but reduced its mRNA stability," said Bao.

<div class="cArrow"> </div><div class="cContentInner">The in vitro study, reported in the journal Carcinogenesis (Vol. 27, pp. 32-42), showed that vitamin D, in the form of the highly active 1alpha, 25-dihydroxyvitamin D3 (1,25-VD), inhibited the function of protease enzymes that are involved in tumour invasion. "We found that 1,25-VD decreased matric metalloproteinases (MMP-9) and cathepsins (CPs), while it [also] increased the activity of their counterparts, tissue inhibitors of metalloproteinase-1 (TIMP-1) and cathepsin inhibitors," wrote lead author Bo-Ying Bao from the University of Rochester and Taipei Medical University. "Mechanistic studies showed that 1,25-VD did not suppress MMP-9 expression at the transcriptional level, but reduced its mRNA stability," said Bao.</div>

...

Cancel

ScienceDaily: Vitamin D, NSAIDS Provide Double Whammy Against Prostate Cancer, Stanford... - 0 views

www.sciencedaily.com/...050901071930.htm

2005 September sciencedaily news prostate cancer NSAID NSAIDS vitamin D vitamin_D prostate_cancer PCa growth-inhibitory calcitriol

shared by Matti Narkia on 24 Feb 09 - Cached

Matti Narkia on 24 Feb 09

ScienceDaily (Sep. 1, 2005) - STANFORD, Calif. - The growth of prostate cancer cells can be halted by combining a form of vitamin D, available only by prescription, with low doses of an over-the-counter painkiller, researchers at the Stanford University School of Medicine have found. The combination reduced prostate cancer cell growth in a laboratory dish by up to 70 percent, according to the findings, published in the Sept. 1 issue of Cancer Research.

<div class="cArrow"> </div><div class="cContentInner">ScienceDaily (Sep. 1, 2005) - STANFORD, Calif. - The growth of prostate cancer cells can be halted by combining a form of vitamin D, available only by prescription, with low doses of an over-the-counter painkiller, researchers at the Stanford University School of Medicine have found. The combination reduced prostate cancer cell growth in a laboratory dish by up to 70 percent, according to the findings, published in the Sept. 1 issue of Cancer Research.</div>

...

Cancel

Vitamin D boosts NSAID cancer-fighting power - 0 views

www.nutraingredients.com/...ng.asp

2005 September news sunshine sun prostate cancer prostate_cancer PCa NSAID NSAIDs growth-inhibitory calcitriol vitamin D vitamin_D

shared by Matti Narkia on 24 Feb 09 - Cached

Matti Narkia on 24 Feb 09

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs act as a powerful combination to halt the growth of prostate cancer cells, say US scientists. Writing in Cancer Research, a team from Stanford University says it discovered that the amount of both activated vitamin D, or calcitriol, and NSAIDs could be reduced by half to one-tenth the dosage to thwart prostate cancer cell growth in cell lines and primary tissue culture

<div class="cArrow"> </div><div class="cContentInner">Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs act as a powerful combination to halt the growth of prostate cancer cells, say US scientists. Writing in Cancer Research, a team from Stanford University says it discovered that the amount of both activated vitamin D, or calcitriol, and NSAIDs could be reduced by half to one-tenth the dosage to thwart prostate cancer cell growth in cell lines and primary tissue culture</div>

...

Cancel

Vitamin D May Cut Pancreatic Cancer - 0 views

www.webmd.com/...116673.htm

2006 September WebMD cancer nutrition pancreatic pancreatic_cancer prevention sunshine sun vitamin D vitamin_D

shared by Matti Narkia on 24 Feb 09 - Cached

Matti Narkia on 24 Feb 09

Sept. 12, 2006 -- Getting the recommended intake of vitamin D from diet, supplements, or even the sun may cut your risk of pancreatic cancer. The results of two large, long-term surveys show that adults who got 300 IU to 449 IU (international units) per day had a 43% lower risk of pancreatic cancer. The recommended intake of vitamin D for adults aged 51-70 is 400 IU per day.

<div class="cArrow"> </div><div class="cContentInner">Sept. 12, 2006 -- Getting the recommended intake of vitamin D from diet, supplements, or even the sun may cut your risk of pancreatic cancer. The results of two large, long-term surveys show that adults who got 300 IU to 449 IU (international units) per day had a 43% lower risk of pancreatic cancer. The recommended intake of vitamin D for adults aged 51-70 is 400 IU per day.</div>

...

Cancel

ScienceDaily: Vitamin D Inhibits Progression Of Some Prostate Cancers - 0 views

Matti Narkia on 24 Feb 09

ScienceDaily (Feb. 8, 2006) - Vitamin D can inhibit the spread of prostate cancer cells by limiting the activity of two specific enzymes, University of Rochester Medical Center scientists report. \n\nThe finding means that vitamin D could provide beneficial treatment to prostate cancer patients with high levels of the enzymes, the scientists said.\n

<div class="cArrow"> </div><div class="cContentInner">ScienceDaily (Feb. 8, 2006) - Vitamin D can inhibit the spread of prostate cancer cells by limiting the activity of two specific enzymes, University of Rochester Medical Center scientists report. \n\nThe finding means that vitamin D could provide beneficial treatment to prostate cancer patients with high levels of the enzymes, the scientists said.\n</div>

...

Cancel

High-dose vitamin C therapy: Renewed hope or false promise? -- Assouline and Miller 174... - 0 views

www.cmaj.ca/...956

2006 March CMAJ study review High-dose vitamin C vitamin_C cancer therapy intravenous IV treatment medline experimental

shared by Matti Narkia on 24 Feb 09 - Cached

Matti Narkia on 24 Feb 09

High-dose vitamin C therapy: renewed hope or false promise?\nAssouline S, Miller WH.\nCMAJ. 2006 Mar 28;174(7):956-7. \nPMID: 16567756

<div class="cArrow"> </div><div class="cContentInner">High-dose vitamin C therapy: renewed hope or false promise?\nAssouline S, Miller WH.\nCMAJ. 2006 Mar 28;174(7):956-7. \nPMID: 16567756</div>

...

Cancel

Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health o... - 0 views

Matti Narkia on 25 Feb 09

Bischoff-Ferrari HA, Giovannucci E, Willett WC, Dietrich T, Dawson-Hughes B. Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes. Am J Clin Nutr. 2006 Jul;84(1):18-28. Review. PMID: 16825677

<div class="cArrow"> </div><div class="cContentInner">Bischoff-Ferrari HA, Giovannucci E, Willett WC, Dietrich T, Dawson-Hughes B. Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes. Am J Clin Nutr. 2006 Jul;84(1):18-28. Review. PMID: 16825677</div>

...

Cancel

DCA, Dichloroacetate for Cancer - Dr. Weil - 0 views

www.drweil.com/...DCA-Hope-or-Hype.html

2008 January drweil DCA cancer Dichloroacetate info question answer qa

shared by Matti Narkia on 24 Feb 09 - Cached

Matti Narkia on 24 Feb 09

DCA is an organic compound, and a byproduct of TCE (trichloroethylene), a chemical that has been a concern in the development of cancer. In January 2007, researchers at the University of Alberta published a study in the journal Cancer Cell suggesting that DCA showed promise in shrinking tumors in lab rats as well as inhibiting growth of cultured human cancer cells. They hypothesized that DCA may be able to change cancer cells back to normal ones by switching them from the aberrant energy pathways they rely on to those used by normal cells.

<div class="cArrow"> </div><div class="cContentInner">DCA is an organic compound, and a byproduct of TCE (trichloroethylene), a chemical that has been a concern in the development of cancer. In January 2007, researchers at the University of Alberta published a study in the journal Cancer Cell suggesting that DCA showed promise in shrinking tumors in lab rats as well as inhibiting growth of cultured human cancer cells. They hypothesized that DCA may be able to change cancer cells back to normal ones by switching them from the aberrant energy pathways they rely on to those used by normal cells.</div>

...

Cancel

Dichloroacetate (DCA) Promising for Endometrial Cancer - Cancer Treatments / Therapy R... - 0 views

www.cancermonthly.com/...view.asp

2008 July news DCA cancer Endometrial_Cancer Endometrial Dichloroacetate

shared by Matti Narkia on 24 Feb 09 - Cached

Matti Narkia on 24 Feb 09

Dichloroacetate (DCA), a drug that has been used for many years in patients with metabolic disorders, has recently been gaining attention for its cancer-fighting capabilities. Studies in the lab have already shown its potential against lung, breast and glioblastoma cancer cells. Now a new study in the journal Gynecoogic Oncology finds that DCA might also be a promising therapy for endometrial cancer.

<div class="cArrow"> </div><div class="cContentInner">Dichloroacetate (DCA), a drug that has been used for many years in patients with metabolic disorders, has recently been gaining attention for its cancer-fighting capabilities. Studies in the lab have already shown its potential against lung, breast and glioblastoma cancer cells. Now a new study in the journal Gynecoogic Oncology finds that DCA might also be a promising therapy for endometrial cancer.</div>

...

Cancel

Cancer

Green tea may negate the effects of a common cancer therapy - 0 views

Older Men Urged to Consider a Drug to Prevent Prostate Cancer - NYTimes.com - 0 views

Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective -... - 0 views

AICR: Second Expert Report: Food, Nutrition, Physical Activity, and the Prevention of C... - 0 views

AICR: Policy Report: Policy and Action for Cancer Prevention - 0 views

Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and h... - 0 views

Phase I clinical trial of i.v. ascorbic acid in advanced malignancy. - Ann Oncol. 2008 ... - 0 views

Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive ... - 0 views

Vitamin C and cancer revisited - PNAS - 0 views

Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a p... - 0 views

Differential effects of selenium on benign and malignant prostate epithelial cells: sti... - 0 views

Vitamin D may inhibit prostate cancer growth - mechanism reported - 0 views

ScienceDaily: Vitamin D, NSAIDS Provide Double Whammy Against Prostate Cancer, Stanford... - 0 views

Vitamin D boosts NSAID cancer-fighting power - 0 views

Vitamin D May Cut Pancreatic Cancer - 0 views

ScienceDaily: Vitamin D Inhibits Progression Of Some Prostate Cancers - 0 views

High-dose vitamin C therapy: Renewed hope or false promise? -- Assouline and Miller 174... - 0 views

Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health o... - 0 views

DCA, Dichloroacetate for Cancer - Dr. Weil - 0 views

Dichloroacetate (DCA) Promising for Endometrial Cancer - Cancer Treatments / Therapy R... - 0 views

View AllMost Active Members

View AllTop 10 Tags