Contents contributed and discussions participated by Matti Narkia - Cancer

Cancer Journal: Latest cancer research WCRF: Major cancer prevention report | ecancerme... - 0 views

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2009 February news WCRF Policy Report Cancer Prevention Cancer_Prevention action nutrition lifestyle

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Matti Narkia on 27 Feb 09

World Cancer Research Fund launches new policy report: 'Policy and action for cancer prevention'\nOver 40 per cent of bowel and breast cancer cases in the UK are preventable through healthy patterns of diet, physical activity and weight maintenance, according to estimates in a landmark report that has set out recommendations for policies and actions to reduce the global number of cancer cases.\nThe report, Policy and Action for Cancer Prevention, has estimated that about 43 per cent of bowel cancer cases and 42 per cent of breast cancer cases in the UK could be prevented in this way.

<div class="cArrow"> </div><div class="cContentInner">World Cancer Research Fund launches new policy report: 'Policy and action for cancer prevention'\nOver 40 per cent of bowel and breast cancer cases in the UK are preventable through healthy patterns of diet, physical activity and weight maintenance, according to estimates in a landmark report that has set out recommendations for policies and actions to reduce the global number of cancer cases.\nThe report, Policy and Action for Cancer Prevention, has estimated that about 43 per cent of bowel cancer cases and 42 per cent of breast cancer cases in the UK could be prevented in this way.</div>

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The controversial place of vitamin C in cancer treatment - ScienceDirect - Biochemical ... - 0 views

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2008 December study review humans vitamin C vitamin_C high-dose IV intravenous cancer treatment therapy controversial experimental nutrition medline

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Matti Narkia on 27 Feb 09

The controversial place of vitamin C in cancer treatment. Verrax J, Calderon PB. Biochem Pharmacol. 2008 Dec 15;76(12):1644-52. Epub 2008 Sep 30. Review. PMID: 18938145 doi:10.1016/j.bcp.2008.09.024

<div class="cArrow"> </div><div class="cContentInner">The controversial place of vitamin C in cancer treatment. Verrax J, Calderon PB. Biochem Pharmacol. 2008 Dec 15;76(12):1644-52. Epub 2008 Sep 30. Review. PMID: 18938145 doi:10.1016/j.bcp.2008.09.024 </div>

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A pilot clinical study of continuous intravenous a...[P R Health Sci J. 2005] - PubMed ... - 0 views

Matti Narkia on 27 Feb 09

A pilot clinical study of continuous intravenous ascorbate in terminal cancer patients. Riordan HD, Casciari JJ, González MJ, Riordan NH, Miranda-Massari JR, Taylor P, Jackson JA. P R Health Sci J. 2005 Dec;24(4):269-76. PMID: 16570523

<div class="cArrow"> </div><div class="cContentInner">A pilot clinical study of continuous intravenous ascorbate in terminal cancer patients. Riordan HD, Casciari JJ, González MJ, Riordan NH, Miranda-Massari JR, Taylor P, Jackson JA. P R Health Sci J. 2005 Dec;24(4):269-76. PMID: 16570523</div>

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Changes of terminal cancer patients' health-related quality of life after high dose vit... - 0 views

Matti Narkia on 27 Feb 09

Changes of terminal cancer patients' health-related quality of life after high dose vitamin C administration.\nYeom CH, Jung GC, Song KJ.\nJ Korean Med Sci. 2007 Feb;22(1):7-11.\nPMID: 17297243

<div class="cArrow"> </div><div class="cContentInner">Changes of terminal cancer patients' health-related quality of life after high dose vitamin C administration.\nYeom CH, Jung GC, Song KJ.\nJ Korean Med Sci. 2007 Feb;22(1):7-11.\nPMID: 17297243</div>

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Technology Review: Implant Makes Cells Kill Cancer - 0 views

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2009 January news implant biomaterial cancer immunotherapy polymer therapy immune system treatment experimental new

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Matti Narkia on 27 Feb 09

A new approach to cancer treatment called immunotherapy could spare patients at least some of the grueling battery of chemotherapy treatments by retraining the body's own defenders--the cells of the immune system--to recognize and destroy tumors. Now researchers at Harvard University have developed a simple way to do this inside the body: a polymer implant attracts and trains immune-system cells to go after cancer. The experimental approach has shown great success in animal studies, increasing the survival rate of mice with a deadly melanoma from 0 to 90 percent. The implant could also be used to treat diseases of the immune system such as arthritis and diabetes, and, potentially, to train other kinds of cells, including stem cells used to repair damage to the body.

<div class="cArrow"> </div><div class="cContentInner">A new approach to cancer treatment called immunotherapy could spare patients at least some of the grueling battery of chemotherapy treatments by retraining the body's own defenders--the cells of the immune system--to recognize and destroy tumors. Now researchers at Harvard University have developed a simple way to do this inside the body: a polymer implant attracts and trains immune-system cells to go after cancer. The experimental approach has shown great success in animal studies, increasing the survival rate of mice with a deadly melanoma from 0 to 90 percent. The implant could also be used to treat diseases of the immune system such as arthritis and diabetes, and, potentially, to train other kinds of cells, including stem cells used to repair damage to the body.</div>

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Intravenous vitamin C as a chemotherapy agent: a r...[P R Health Sci J. 2004] - PubMed ... - 0 views

Matti Narkia on 27 Feb 09

Intravenous vitamin C as a chemotherapy agent: a report on clinical cases.\nRiordan HD, Riordan NH, Jackson JA, Casciari JJ, Hunninghake R, González MJ, Mora EM, Miranda-Massari JR, Rosario N, Rivera A.\nP R Health Sci J. 2004 Jun;23(2):115-8.\nPMID: 15377059

<div class="cArrow"> </div><div class="cContentInner">Intravenous vitamin C as a chemotherapy agent: a report on clinical cases.\nRiordan HD, Riordan NH, Jackson JA, Casciari JJ, Hunninghake R, González MJ, Mora EM, Miranda-Massari JR, Rosario N, Rivera A.\nP R Health Sci J. 2004 Jun;23(2):115-8.\nPMID: 15377059</div>

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Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and h... - 0 views

Matti Narkia on 27 Feb 09

Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo.\nChen Q, Espey MG, Sun AY, Lee JH, Krishna MC, Shacter E, Choyke PL, Pooput C, Kirk KL, Buettner GR, Levine M.\nProc Natl Acad Sci U S A. 2007 May 22;104(21):8749-54. Epub 2007 May 14.\nPMID: 17502596 \n doi: 10.1073/pnas.0702854104\n

<div class="cArrow"> </div><div class="cContentInner">Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo.\nChen Q, Espey MG, Sun AY, Lee JH, Krishna MC, Shacter E, Choyke PL, Pooput C, Kirk KL, Buettner GR, Levine M.\nProc Natl Acad Sci U S A. 2007 May 22;104(21):8749-54. Epub 2007 May 14.\nPMID: 17502596 \n doi: 10.1073/pnas.0702854104\n</div>

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Intravenously administered vitamin C as cancer therapy: three cases. - CMAJ. 2006 Mar 28 - 0 views

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Matti Narkia on 27 Feb 09

Intravenously administered vitamin C as cancer therapy: three cases.\nPadayatty SJ, Riordan HD, Hewitt SM, Katz A, Hoffer LJ, Levine M.\nCMAJ. 2006 Mar 28;174(7):937-42.\nPMID: 16567755 \ndoi:10.1503/cmaj.050346.

<div class="cArrow"> </div><div class="cContentInner">Intravenously administered vitamin C as cancer therapy: three cases.\nPadayatty SJ, Riordan HD, Hewitt SM, Katz A, Hoffer LJ, Levine M.\nCMAJ. 2006 Mar 28;174(7):937-42.\nPMID: 16567755 \ndoi:10.1503/cmaj.050346.</div>

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Phase I clinical trial of i.v. ascorbic acid in advanced malignancy. - Ann Oncol. 2008 ... - 0 views

Matti Narkia on 27 Feb 09

Phase I clinical trial of i.v. ascorbic acid in advanced malignancy. Hoffer LJ, Levine M, Assouline S, Melnychuk D, Padayatty SJ, Rosadiuk K, Rousseau C, Robitaille L, Miller WH Jr. Ann Oncol. 2008 Nov;19(11):1969-74. Epub 2008 Jun 9. Erratum in: Ann Oncol. 2008 Dec;19(12):2095. PMID: 18544557 doi:10.1093/annonc/mdn377

<div class="cArrow"> </div><div class="cContentInner">Phase I clinical trial of i.v. ascorbic acid in advanced malignancy. Hoffer LJ, Levine M, Assouline S, Melnychuk D, Padayatty SJ, Rosadiuk K, Rousseau C, Robitaille L, Miller WH Jr. Ann Oncol. 2008 Nov;19(11):1969-74. Epub 2008 Jun 9. Erratum in: Ann Oncol. 2008 Dec;19(12):2095. PMID: 18544557 doi:10.1093/annonc/mdn377 </div>

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Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a p... - 0 views

Matti Narkia on 27 Feb 09

Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues. Chen Q, Espey MG, Krishna MC, Mitchell JB, Corpe CP, Buettner GR, Shacter E, Levine M. Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13604-9. Epub 2005 Sep 12. PMID: 16157892

<div class="cArrow"> </div><div class="cContentInner">Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues. Chen Q, Espey MG, Krishna MC, Mitchell JB, Corpe CP, Buettner GR, Shacter E, Levine M. Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13604-9. Epub 2005 Sep 12. PMID: 16157892</div>

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Vitamin C and cancer revisited - PNAS - 0 views

Matti Narkia on 27 Feb 09

Vitamin C and cancer revisited. Frei B, Lawson S. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11037-8. Epub 2008 Aug 5. PMID: 18682554

<div class="cArrow"> </div><div class="cContentInner">Vitamin C and cancer revisited. Frei B, Lawson S. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11037-8. Epub 2008 Aug 5. PMID: 18682554</div>

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Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive ... - 0 views

Matti Narkia on 27 Feb 09

Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice. Chen Q, Espey MG, Sun AY, Pooput C, Kirk KL, Krishna MC, Khosh DB, Drisko J, Levine M. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11105-9. Epub 2008 Aug 4. PMID: 18678913 doi: 10.1073/pnas.0804226105

<div class="cArrow"> </div><div class="cContentInner">Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice. Chen Q, Espey MG, Sun AY, Pooput C, Kirk KL, Krishna MC, Khosh DB, Drisko J, Levine M. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11105-9. Epub 2008 Aug 4. PMID: 18678913 doi: 10.1073/pnas.0804226105 </div>

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Differential effects of selenium on benign and malignant prostate epithelial cells: sti... - 0 views

Matti Narkia on 27 Feb 09

Differential effects of selenium on benign and malignant prostate epithelial cells: stimulation of LNCaP cell growth by noncytotoxic, low selenite concentrations. Kandaş NO, Randolph C, Bosland MC. Nutr Cancer. 2009;61(2):251-64. PMID: 19235042

<div class="cArrow"> </div><div class="cContentInner">Differential effects of selenium on benign and malignant prostate epithelial cells: stimulation of LNCaP cell growth by noncytotoxic, low selenite concentrations. Kandaş NO, Randolph C, Bosland MC. Nutr Cancer. 2009;61(2):251-64. PMID: 19235042 </div>

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AICR: Second Expert Report: Food, Nutrition, Physical Activity, and the Prevention of C... - 0 views

Matti Narkia on 26 Feb 09

Second Expert Report\n\nFood, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective\n\nIt began in 2001 with AICR and its international affiliate, WCRF-UK committing themselves to systematically review and analyze the total body of scientific evidence on the relationship of diet, physical activity and weight management to cancer risk. After a rigorous five-year process, Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective does just that.

<div class="cArrow"> </div><div class="cContentInner">Second Expert Report\n\nFood, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective\n\nIt began in 2001 with AICR and its international affiliate, WCRF-UK committing themselves to systematically review and analyze the total body of scientific evidence on the relationship of diet, physical activity and weight management to cancer risk. After a rigorous five-year process, Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective does just that.</div>

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AICR: Policy Report: Policy and Action for Cancer Prevention - 0 views

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AICR: Policy Report WCRF Cancer Prevention Cancer_Prevention info portal directory action video viseos presentations

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Matti Narkia on 26 Feb 09

Policy Report\n\nLearn more about the new WCRF/AICR report, Policy and Action for Cancer Prevention, which was launched at an international press briefing in London at 10 a.m. GMT (5 a.m. US Eastern Time), and presented to US lawmakers at a Congressional Briefing at 10 a.m. US Eastern Time, on February 26th, 2009.

<div class="cArrow"> </div><div class="cContentInner">Policy Report\n\nLearn more about the new WCRF/AICR report, Policy and Action for Cancer Prevention, which was launched at an international press briefing in London at 10 a.m. GMT (5 a.m. US Eastern Time), and presented to US lawmakers at a Congressional Briefing at 10 a.m. US Eastern Time, on February 26th, 2009.</div>

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Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective -... - 0 views

Matti Narkia on 26 Feb 09

Welcome to dietandcancerreport.org where you can find the WCRF/AICR Expert Report, Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective as well as the companion report, Policy and Action for Cancer Prevention. The most up to date reference and resource materials associated with both reports are available from this site

<div class="cArrow"> </div><div class="cContentInner">Welcome to dietandcancerreport.org where you can find the WCRF/AICR Expert Report, Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective as well as the companion report, Policy and Action for Cancer Prevention. The most up to date reference and resource materials associated with both reports are available from this site</div>

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Indole-3-Carbinol: A Powerful Compound That Can Prevent And Treat Cancer - 0 views

Matti Narkia on 26 Feb 09

Broccoli, cabbage, cauliflower, brussels sprouts, kale and kohlrabi - this family of cruciferous vegetables is naturally rich in indole-3-carbinol (I3C), a compound that is quickly becoming recognized as one of the most powerful cancer-fighting compounds that we know of.

<div class="cArrow"> </div><div class="cContentInner">Broccoli, cabbage, cauliflower, brussels sprouts, kale and kohlrabi - this family of cruciferous vegetables is naturally rich in indole-3-carbinol (I3C), a compound that is quickly becoming recognized as one of the most powerful cancer-fighting compounds that we know of.</div>

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Older Men Urged to Consider a Drug to Prevent Prostate Cancer - NYTimes.com - 0 views

Matti Narkia on 26 Feb 09

For the first time, medical groups have issued guidelines that say healthy older men should consider taking a drug that may reduce their risk of developing prostate cancer, even if they're just among the worried well who go in for regular screenings.\n\nThe drug, finasteride, is already used to treat male pattern baldness and to shrink enlarged prostates. The new guidelines suggest that patients who are already taking finasteride for those conditions or who go for regular prostate cancer screening tests should discuss long-term treatment with the drug with their doctors.

<div class="cArrow"> </div><div class="cContentInner">For the first time, medical groups have issued guidelines that say healthy older men should consider taking a drug that may reduce their risk of developing prostate cancer, even if they're just among the worried well who go in for regular screenings.\n\nThe drug, finasteride, is already used to treat male pattern baldness and to shrink enlarged prostates. The new guidelines suggest that patients who are already taking finasteride for those conditions or who go for regular prostate cancer screening tests should discuss long-term treatment with the drug with their doctors.</div>

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Green tea may negate the effects of a common cancer therapy - 0 views

Matti Narkia on 26 Feb 09

(WASHINGTON, February 3, 2009) - Green tea products have become regarded as a valuable health supplement, as studies have shown evidence of its benefit against a variety of diseases, including cancer. However, a new study suggests that some components of green tea may counteract the anticancer effects of one cancer therapy, bortezomib (Velcade®), and may be contraindicated for patients taking this medicine to ensure its maximum therapeutic benefit. This study is being prepublished online today in Blood, the official journal of the American Society of Hematology.

<div class="cArrow"> </div><div class="cContentInner">(WASHINGTON, February 3, 2009) - Green tea products have become regarded as a valuable health supplement, as studies have shown evidence of its benefit against a variety of diseases, including cancer. However, a new study suggests that some components of green tea may counteract the anticancer effects of one cancer therapy, bortezomib (Velcade®), and may be contraindicated for patients taking this medicine to ensure its maximum therapeutic benefit. This study is being prepublished online today in Blood, the official journal of the American Society of Hematology.</div>

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Black Raspberries Kill Esophageal Cancer Cells - 0 views

Matti Narkia on 25 Feb 09

Research just published in the American Association for Cancer Research's Cancer Prevention Research identifies a class of flavonoids called anthocyanins in black raspberries that's been shown to inhibit cancer cell growth and stimulate apoptosis (the death of cancer cells) in the esophagus of rats treated with an esophageal carcinogen

<div class="cArrow"> </div><div class="cContentInner">Research just published in the American Association for Cancer Research's Cancer Prevention Research identifies a class of flavonoids called anthocyanins in black raspberries that's been shown to inhibit cancer cell growth and stimulate apoptosis (the death of cancer cells) in the esophagus of rats treated with an esophageal carcinogen</div>

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