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Matti Narkia

Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and h... - 0 views

www.pnas.org/...8749.full

2007 May PNAS study research in_vitro in_vivo animal_study rats vitamin C vitamin_C high-dose pharmacologic concentration IV intravenous cancer pharmacokinetics nutrition medline ascorbate_radical H2O2 hydrogen_peroxide

shared by Matti Narkia on 27 Feb 09 - Cached
  • Matti Narkia on 27 Feb 09
     
    Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo.\nChen Q, Espey MG, Sun AY, Lee JH, Krishna MC, Shacter E, Choyke PL, Pooput C, Kirk KL, Buettner GR, Levine M.\nProc Natl Acad Sci U S A. 2007 May 22;104(21):8749-54. Epub 2007 May 14.\nPMID: 17502596 \n doi: 10.1073/pnas.0702854104\n
Matti Narkia

Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a p... - 0 views

www.pnas.org/...13604.full

2005 September PNAS study rseaarch in_vitro vitamin C vitamin_C cancer pharmacologic concentration high-dose H2O2 hydrogen_peroxide cell_death ascorbate_radical nutrition medlinel

shared by Matti Narkia on 27 Feb 09 - Cached
  • Matti Narkia on 27 Feb 09
     
    Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues. Chen Q, Espey MG, Krishna MC, Mitchell JB, Corpe CP, Buettner GR, Shacter E, Levine M. Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13604-9. Epub 2005 Sep 12. PMID: 16157892
Matti Narkia

Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive ... - 0 views

www.pnas.org/...11105.full

2008 August PNAS study research in_vivo animal_study mice vitamin C vitamin_C cancer H2O2 hydrogen_peroxide oxidation free_radicals nutrition medline treatment therapy experimental prooxidant high-dose parenteral IV intravenous infusion

shared by Matti Narkia on 27 Feb 09 - Cached
  • Matti Narkia on 27 Feb 09
     
    Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice. Chen Q, Espey MG, Sun AY, Pooput C, Kirk KL, Krishna MC, Khosh DB, Drisko J, Levine M. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11105-9. Epub 2008 Aug 4. PMID: 18678913 doi: 10.1073/pnas.0804226105
Matti Narkia

Copper Deficiency Induced by Tetrathiomolybdate Suppresses Tumor Growth and Angiogenesi... - 0 views

cancerres.aacrjournals.org/...4854

Copper Deficiency Tetrathiomolybdate Suppresses Tumor cancer Growth Angiogenesis anti-copper anti-angiogenesis anti-angiogenic agent inhibition inhibitor inhibitors medicine medline oncology science study research peer-reviewed treatment therapy imported

shared by Matti Narkia on 24 Feb 09 - Cached
  • Matti Narkia on 24 Feb 09
     
    Q. Pan, C. G. Kleer, K. L. van Golen, J. Irani, K. M. Bottema, C. Bias, M. De Carvalho, E. A. Mesri, D. M. Robins, R. D. Dick, G. J. Brewer, and S. D. Merajver Copper Deficiency Induced by Tetrathiomolybdate Suppresses Tumor Growth and Angiogenesis Canc
Matti Narkia

Phase II Trial of Tetrathiomolybdate in Patients with Advanced Kidney Cancer -- Redman ... - 0 views

clincancerres.aacrjournals.org/...1666

Phase-II phaseII Trial Tetrathiomolybdate Advanced Kidney Cancer renal kidneycancer clinicaltrial anti-angiogenesis anti-angiogenic anti-copper agent angiogenesis copper inhibition inhibitor inhibitors reduction medicine medline oncology science study res

shared by Matti Narkia on 24 Feb 09 - Cached
  • Matti Narkia on 24 Feb 09
     
    B. G. Redman, P. Esper, Q. Pan, R. L. Dunn, H. K. Hussain, T. Chenevert, G. J. Brewer, and S. D. Merajver Phase II Trial of Tetrathiomolybdate in Patients with Advanced Kidney Cancer Clin. Cancer Res., May 1, 2003; 9(5): 1666 - 1672.
Matti Narkia

Antiangiogenic Tetrathiomolybdate Enhances the Efficacy of Doxorubicin against Breast C... - 0 views

mct.aacrjournals.org/...617

anti-angiogenic anti-angiogenesis anti-copper angiogenesis Tetrathiomolybdate Doxorubicin Breast Carcinoma cancer chemotherapy agent inhibition inhibitor inhibitors copper reduction science study research medicine medline peer-reviewed impor breast_cancer

shared by Matti Narkia on 24 Feb 09 - Cached
  • Matti Narkia on 24 Feb 09
     
    Pan Q, Bao LW, Kleer CG, Brewer GJ, Merajver SD. Antiangiogenic tetrathiomolybdate enhances the efficacy of doxorubicin against breast carcinoma. Mol Cancer Ther. 2003 Jul;2(7):617-22. PMID: 12883034 [PubMed - indexed for MEDLINE]
paijo9

Biological Therapies for Cancer: Q & A   | cancerlab.org - 0 views

cancerlab.org/or-cancer-q-a%c2%a0%c2%a0.html

cancer therapy cancer treatment chemotherapy biological therapy

shared by paijo9 on 31 Jul 11 - No Cached
  • paijo9 on 31 Jul 11
     
    Biological therapy is a type of treatment that works with your immune system. It can help fight cancer or help control side effects (how your body reacts to the drugs you are taking) from other cancer treatments like chemotherapy.
Matti Narkia

Frankincense oil derived from Boswellia carteri induces tumor cell specific cytotoxicit... - 0 views

www.biomedcentral.com/1472-6882/9/6/abstract (free full text PDF available)

2009 March study research in_vitro frankincense oil frankincense_oil Boswellia_carteri Boswellia trees herb herbs cam altmed boswellic acid boswellic_acid bladder cancer bladder_cancer anti-cancer anticancer medline

shared by Matti Narkia on 26 Mar 09 - No Cached
  • Matti Narkia on 26 Mar 09
     
    Frankincense oil derived from Boswellia carteri induces tumor cell specific cytotoxicity. Frank MB, Yang Q, Osban J, Azzarello JT, Saban MR, Saban R, Ashley RA, Welter JC, Fung KM, Lin HK. BMC Complement Altern Med. 2009 Mar 18;9(1):6. [Epub ahead of print] PMID: 19296830 doi:10.1186/1472-6882-9-6
Matti Narkia

Tetrathiomolybdate promotes tumor necrosis and prevents distant metastases by suppressi... - 0 views

mct.aacrjournals.org/...1039

Hassouneh B Islam M Nagel T Pan Q Merajver SD Teknos TN. Tetrathiomolybdate promotes tumor necrosis and prevents distant metastases by suppressing angiogenesis in head neck cancer. Mol Cancer Ther. 2007 Mar;6(3):1039-45. PMID: 17363496 [PubMed inhibi

shared by Matti Narkia on 24 Feb 09 - Cached
  • Matti Narkia on 24 Feb 09
     
    Tetrathiomolybdate promotes tumor necrosis and prevents distant metastases by suppressing angiogenesis in head and neck cancer -- Hassouneh et al. 6 (3): 1039 -- Molecular Cancer Therapeutics
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