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Matti Narkia

A 22-y prospective study of fish intake in relation to prostate cancer incidence and mo... - 0 views

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    A 22-y prospective study of fish intake in relation to prostate cancer incidence and mortality.
    Chavarro JE, Stampfer MJ, Hall MN, Sesso HD, Ma J.
    Am J Clin Nutr. 2008 Nov;88(5):1297-303.
    PMID: 18996866

    Conclusion: These results suggest that fish intake is unrelated to prostate cancer incidence but may improve prostate cancer survival.

Matti Narkia

Sham vs. Wham: The Health Insider: Omega 3 In the News Again - Lower Advanced Prostate ... - 0 views

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    new (March 24th) report in Clinical Cancer Research, a journal of the American Association for Cancer Research, shows that Omega-3 fatty acids appear protective against advanced prostate cancer.

    Dr. John S. Witte, Ph.D., professor of epidemiology and biostatistics at the University of California San Francisco, says that previous research has shown protection against prostate cancer, but that this is one of the first studies to show protection against advanced prostate cancer.
Matti Narkia

Dietary Omega-3 Fatty Acids, Cyclooxygenase-2 Genetic Variation, and Aggressive Prostat... - 0 views

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    Dietary Omega-3 Fatty Acids, Cyclooxygenase-2 Genetic Variation, and Aggressive Prostate Cancer Risk.
    Fradet V, Cheng I, Casey G, Witte JS.
    Clin Cancer Res. 2009 Mar 24. [Epub ahead of print]
    PMID: 19318492
    DOI: 10.1158/1078-0432.CCR-08-2503
Matti Narkia

Apoptotic effects of dietary and synthetic sphingolipids in androgen-independent (PC-3)... - 0 views

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    Apoptotic effects of dietary and synthetic sphingolipids in androgen-independent (PC-3) prostate cancer cells.
    Kent KD, Clubbs EA, Harper WJ, Bomser JA.
    Lipids. 2008 Feb;43(2):143-9. Epub 2008 Jan 10.
    PMID: 18188632
    DOI: 10.1007/s11745-007-3148-
Matti Narkia

Folic Acid Supplements Linked To Higher Risk Of Prostate Cancer, Study Shows - 0 views

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    ScienceDaily (Mar. 10, 2009) - A study led by researchers at the University of Southern California (USC) found that men who took a daily folic acid supplement of 1 mg daily had more than twice the risk of prostate cancer compared with men who took a placebo.
Matti Narkia

White button mushroom (Agaricus bisporus) exhibits...[Nutr Cancer. 2008] - PubMed Result - 0 views

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    White button mushroom (Agaricus bisporus) exhibits antiproliferative and proapoptotic properties and inhibits prostate tumor growth in athymic mice.
    Adams LS, Phung S, Wu X, Ki L, Chen S.
    Nutr Cancer. 2008;60(6):744-56.
    PMID: 19005974
Matti Narkia

Support ellagic acid therapy in patients with hormone refractory prostate cancer (HRPC)... - 0 views

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    Support ellagic acid therapy in patients with hormone refractory prostate cancer (HRPC) on standard chemotherapy using vinorelbine and estramustine phosphate.
    Falsaperla M, Morgia G, Tartarone A, Ardito R, Romano G.
    Eur Urol. 2005 Apr;47(4):449-54; discussion 454-5. Epub 2005 Jan 19.
    PMID: 15774240
    doi:10.1016/j.eururo.2004.12.001
Matti Narkia

Differential effects of selenium on benign and malignant prostate epithelial cells: sti... - 0 views

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    Differential effects of selenium on benign and malignant prostate epithelial cells: stimulation of LNCaP cell growth by noncytotoxic, low selenite concentrations.
    Kandaş NO, Randolph C, Bosland MC.
    Nutr Cancer. 2009;61(2):251-64.
    PMID: 19235042
Matti Narkia

Older Men Urged to Consider a Drug to Prevent Prostate Cancer - NYTimes.com - 0 views

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    For the first time, medical groups have issued guidelines that say healthy older men should consider taking a drug that may reduce their risk of developing prostate cancer, even if they're just among the worried well who go in for regular screenings.\n\nThe drug, finasteride, is already used to treat male pattern baldness and to shrink enlarged prostates. The new guidelines suggest that patients who are already taking finasteride for those conditions or who go for regular prostate cancer screening tests should discuss long-term treatment with the drug with their doctors.
Matti Narkia

The blueberry drink that can shrink tumours | Mail Online - 0 views

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    Blueberry Punch is an Australian product but is available for sale on the internet at £16 a bottle.\n\nIt also includes a host of other natural ingredients thought to boost health, including green tea, olive leaves, the herb tarragon and the spices turmeric and ginger.\n\nIt is thought the ingredients act together to cut inflammation and block a cancer gene.\n\nDr Jas Singh, who conducted the research on mice at Sydney University, said: "We have undertaken efficacy studies on individual components of Blueberry Punch in the same laboratory setting and found these effective in suppressing cell growth in culture.\n\n"We reasoned that synergistic or additive effects are likely to be achieved when they are combined."\n\nThe researchers looked at the effect of Blueberry Punch on both cancer cell cultures in the laboratory and genetically engineered mice with human prostate tumours. After only two weeks of having the syrupy solution added to their drinking water, their tumours had shrunk by
Matti Narkia

Dichloroacetate (DCA) sensitizes both wild-type and over expressing Bcl-2 prostate canc... - 0 views

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    Dichloroacetate (DCA) sensitizes both wild-type and over expressing Bcl-2 prostate cancer cells in vitro to radiation.
    Cao W, Yacoub S, Shiverick KT, Namiki K, Sakai Y, Porvasnik S, Urbanek C, Rosser CJ.
    Prostate. 2008 Aug 1;68(11):1223-31.
    PMID: 18465755
    DOI: 10.1002/pros.20788
Matti Narkia

ScienceDaily: Vitamin D Inhibits Progression Of Some Prostate Cancers - 0 views

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    ScienceDaily (Feb. 8, 2006) - Vitamin D can inhibit the spread of prostate cancer cells by limiting the activity of two specific enzymes, University of Rochester Medical Center scientists report. \n\nThe finding means that vitamin D could provide beneficial treatment to prostate cancer patients with high levels of the enzymes, the scientists said.\n
Matti Narkia

Vitamin D may inhibit prostate cancer growth - mechanism reported - 0 views

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    The in vitro study, reported in the journal Carcinogenesis (Vol. 27, pp. 32-42), showed that vitamin D, in the form of the highly active 1alpha, 25-dihydroxyvitamin D3 (1,25-VD), inhibited the function of protease enzymes that are involved in tumour invasion.

    "We found that 1,25-VD decreased matric metalloproteinases (MMP-9) and cathepsins (CPs), while it [also] increased the activity of their counterparts, tissue inhibitors of metalloproteinase-1 (TIMP-1) and cathepsin inhibitors," wrote lead author Bo-Ying Bao from the University of Rochester and Taipei Medical University.

    "Mechanistic studies showed that 1,25-VD did not suppress MMP-9 expression at the transcriptional level, but reduced its mRNA stability," said Bao.
Matti Narkia

Vitamin D boosts NSAID cancer-fighting power - 0 views

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    Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs act as a powerful combination to halt the growth of prostate cancer cells, say US scientists.
    Writing in Cancer Research, a team from Stanford University says it discovered that the amount of both activated vitamin D, or calcitriol, and NSAIDs could be reduced by half to one-tenth the dosage to thwart prostate cancer cell growth in cell lines and primary tissue culture
Matti Narkia

ScienceDaily: Vitamin D, NSAIDS Provide Double Whammy Against Prostate Cancer, Stanford... - 0 views

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    ScienceDaily (Sep. 1, 2005) - STANFORD, Calif. - The growth of prostate cancer cells can be halted by combining a form of vitamin D, available only by prescription, with low doses of an over-the-counter painkiller, researchers at the Stanford University School of Medicine have found. The combination reduced prostate cancer cell growth in a laboratory dish by up to 70 percent, according to the findings, published in the Sept. 1 issue of Cancer Research.
Matti Narkia

In-vitro effects of polyphenols from cocoa and beta-sitosterol on the growth of human p... - 0 views

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    Jourdain C, Tenca G, Deguercy A, Troplin P, Poelman D. In-vitro effects of polyphenols from cocoa and beta-sitosterol on the growth of human prostate cancer and normal cells.
    Eur J Cancer Prev. 2006 Aug;15(4):353-61.
    PMID: 16835506 [PubMed - indexed fo
Matti Narkia

Silibinin synergizes with mitoxantrone to inhibit cell growth and induce apoptosis in h... - 0 views

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    Flaig TW, Su LJ, Harrison G, Agarwal R, Glode LM.
    Silibinin synergizes with mitoxantrone to inhibit cell growth and induce apoptosis in human prostate cancer cells.
    Int J Cancer. 2007 Jan 17; [Epub ahead of print]
    PMID: 17230508 [PubMed - as supplied
Matti Narkia

A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients. -... - 0 views

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    Flaig TW, Gustafson DL, Su LJ, Zirrolli JA, Crighton F, Harrison GS, Pierson AS, Agarwal R, Glode LM.
    A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients.
    Invest New Drugs. 2007 Apr;25(2):139-46. Epub 2006 Nov 1.
    PMID
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