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Ellen Silbergeld keeps the price of gold posted on the door to her office at the Johns Hopkins Bloomberg School of Public Health in Baltimore. The price is now at a record high (better than $1,500 an ounce) and Silbergeld, professor at Hopkins and editor-in-chief of the journal Environmental Research knows that is really bad news for the Amazon.

A class of engineered nanoparticles -- gold-centered spheres smaller than viruses -- has been shown safe when administered by two alternative routes in a mouse study led by investigators at the Stanford University School of Medicine. This marks the first step up the ladder of toxicology studies that, within a year and a half, could yield to human trials of the tiny agents for detection of colorectal and possibly other cancers.