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Tero Toivanen

Research Unearths New Treatments for Autism - 2 views

www.apa.org/...pi4.html

autism research TEACCH Young Autism Project Lovaas DIR ABA PRT Pivotal Response Training social engagement system middle ear music intensity

shared by Tero Toivanen on 01 Jul 09 - Cached
  • The Utah researchers found that children receiving a combination of the two treatments (Lovaas-type training at school and TEACCH methods at home) showed three to four times greater progress on all outcome tests than did children who received only the school-based treatment. That study was reported in the Journal of Autism and Developmental Disorders (Vol. 28, No. 1, p. 2532).
  • Researchers in Washington, D.C., are comparing a discrete trial training approach with a "developmental, individual-difference, relationship based" (DIR) approach, says child psychiatrist Stanley Greenspan, MD, professor of psychiatry at George Washington University Medical School.
  • Psychologist Robert Koegel, PhD, at the University of California, Santa Barbara, and his colleagues are attempting to tailor a standard treatment to the specific needs of an autistic child and family. The standard treatment is called pivotal response training
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  • An initial retrospective study is comparing two groups of 20 children initially diagnosed with autism who were functioning well after two or more years of treatment, either with a discrete trial training approach or the DIR approach. The study aims to determine if treatment differences lead to subtle differences in outcome, for example, in terms of flexibility, emotional range, creativity and richness of the child's inner life. Investigators are planning to follow this research with a prospective, randomized, more rigorous study of the two approaches.
  • "In our previous studies we found out that it looks like you can't just deliver a standard treatment to autistic kids, that there's so much variability among the children that what works for one child doesn't work for another child," he says. "Our hypothesis is that...unless you individualize treatment, you're not going to get the best effect."
  • Researchers at the University of Maryland are testing an intervention to trigger children's "social engagement system," which includes behaviors such as listening, looking, facial expressions and vocalizations that support social interaction, says psychologist Stephen Porges, PhD. The treatment is designed to improve autistic children's ability to interact with others, thereby making them more receptive to traditional therapies.
  • The intervention is based on the theory that tensing the middle ear muscles enables people to pick out the human voice from lower frequency sounds in the environment, Porges says. Treatment involves exercising middle ear muscles by playing music that has been altered to include only frequencies associated with the human voice, which improves one's ability to listen to human voices. This, in turn, stimulates the entire social engagement system, Porges says. About 80 percent of 50 children with autism or other behavioral problems receiving this treatment via five 45-minute sessions in a double blind, randomized controlled study showed marked improvements in listening, language and other communication skills.
  • In a report last year in the Journal of Autism and Developmental Disorders (Vol. 28, No. 1, p. 15-23) evaluating an intensive home-based discrete trial training intervention, Stephen Sheinkopf, PhD, of the University of Miami and Bryna Siegel, PhD, of the University of California, San Francisco, noted that children receiving an average of only 21 hours per week of treatment showed gains in IQ comparable to those achieved by children receiving 32 hours per week. The intensity question remains an issue of importance for the autism community. "If we need 40 hours a week, fine," says psychologist Geraldine Dawson, PhD, of the University of Washington. "But if you only need 25, you have to realize that 40 hours is a tremendous burden not only financially, but on families and on the child."
  • Tero Toivanen on 01 Jul 09
     
    Several treatments, and combinations of treatments, are under intense study.
Tero Toivanen

Facilitated communication: Facts, Discussion Forum, and Encyclopedia Article - 1 views

www.absoluteastronomy.com/...Facilitated_communication

autism Facilitated Communication FC facilitator dyspraxia mental retardation research Independent Typing

shared by Tero Toivanen on 14 Mar 10 - Cached
  • The procedure is controversial, since a majority of peer reviewPeer reviewPeer review is the process of subjecting an author's scholarly work, research, or ideas to the scrutiny of others who are experts in the same field. Peer review requires a community of experts in a given field, who are qualified and able to perform impartial review...ed scientific studies conclude that the typed language output attributed to the clients is directed or systematically determined by the therapists who provide facilitated assistance. Some peer-reviewed scientific studies have indicated instances of valid FC, and some FC users have reportedly gone on to type independently.
  • Harvard UniversityHarvard UniversityHarvard University is a private university located in Cambridge, Massachusetts and a member of the Ivy League. Founded in 1636 by the colonial Massachusetts legislature, Harvard is the oldest institution of higher learning in the United States and currently comprises ten separate academic units... psychologist Daniel WegnerDaniel WegnerDaniel M. Wegner is an American social psychologist. He is a professor of psychology at Harvard University and a fellow of the American Association for the Advancement of Science. He is known for his work on mental control and conscious will, and for originating the study of transactive memory and... has argued that facilitated communication is a striking example of the ideomotor effectIdeomotor effectThe ideomotor effect is a psychological phenomenon wherein a subject makes motions unconsciously. As in reflexive responses to pain, the body sometimes reacts reflexively to ideas alone without the person consciously deciding to take action..., the well-known phenomenon whereby individuals' expectations exert unconscious influence over their motor actions. Even FC users and proponents do acknowledge the possibility of facilitators at times "guiding" users, consciously or unconsciously. Other theorists (Donnellan and Leary, 1995) argue that autism is in significant part characterized by dyspraxia (a movement disorder), and that there exists a synchronistic "dance" to communication in all mammalian social interaction which accounts for the mixed results in validation studies.
  • Stephen von Tetzchner, the author of another leading textbook on Augmentative and Alternative CommunicationAugmentative and alternative communicationAugmentative and alternative communication is communication for those with impairments or restrictions on the production or comprehension of spoken or written language.-Definition :... has done theoretical research about facilitated communication. In his opinion "The existing evidence clearly demonstrates that facilitating techniques usually led to automatic writingAutomatic writingAutomatic writing is the process or production of writing material that does not come from the conscious thoughts of the writer. Practitioners say that the writer's hand forms the message, with the person being unaware of what will be written...., displaying the thoughts and the attitudes of the facilitators."
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  • Mark Mostert (2001) says: "Previous reviews of Facilitated Communication (FC) studies have clearly established that proponents' claims are largely unsubstantiated and that using FC as an intervention for communicatively impaired or noncommunicative individuals is not recommended." In March 2007, Scott Lilienfeld included facilitated communication on a list of treatments that have the potential to cause harm in clients, published in the APSAssociation for Psychological ScienceThe Association for Psychological Science , previously the American Psychological Society, is a non-profit organization whose mission is to promote, protect, and advance the interests of scientifically oriented psychology in research, application, teaching, and the improvement of human welfare... journal Perspectives on Psychological Science.
  • The phrase "independent typing" is defined by supporters of FC as "typing without physical support", i.e., without being touched by another person. Skeptics of FC do not agree that this definition of independence suffices because of the possibility of influence by the facilitator. For example, Sue RubinSue RubinSue Rubin is a functionally non-verbal published autistic author who was the subject of the Oscar-nominated documentary Autism Is A World in which she communicated via the controversial communication technique of facilitated communication...., an FC user featured in the autobiographical documentary Autism Is A World, reportedly types without anyone touching her; however, she reports that she requires a facilitator to hold the keyboard and offer other assistance.
  • Tero Toivanen on 14 Mar 10
     
    The procedure is controversial, since a majority of peer reviewed scientific studies conclude that the typed language output attributed to the clients is directed or systematically determined by the therapists who provide facilitated assistance. Some peer-reviewed scientific studies have indicated instances of valid FC, and some FC users have reportedly gone on to type independently.
Tero Toivanen

Autism-like behaviors reversed in mice: New hope for understanding autism - 3 views

www.sciencedaily.com/...121121145402.htm

autism research

shared by Tero Toivanen on 22 Nov 12 - No Cached
  • Tero Toivanen on 22 Nov 12
     
    "Researchers from McGill University and the University of Montreal have identified a crucial link between protein synthesis and autism spectrum disorders (ASD), which can bolster new therapeutic avenues."
Graeme Wadlow

Cultural Confusions Show that Facial Expressions Are Not Universal - 0 views

www.cell.com/...S0960982209014778

Adult; Confusion; Cross-Cultural Comparison; Cultural Characteristics; Culture; Emotions; Eye Movements; universal

shared by Graeme Wadlow on 04 Jan 12 - No Cached
  • Graeme Wadlow on 04 Jan 12
     
    Current Biology - Cultural Confusions Show that Facial Expressions Are Not Universal
Amanda Kenuam

Online Special Education Resources from FDLRS/TECH - 0 views

www.mangomon.com/...tion-Resources-from-FDLRS-TECH

special education Florida Department of Education Universal Design for Learning Assistive Tech Simple Tech Reading Writing Math Science Creativity

shared by Amanda Kenuam on 08 Mar 10 - Cached
  • Amanda Kenuam on 08 Mar 10
     
    " special education, Florida Department of Education, Universal Design for Learning, Assistive Tech, Simple Tech, Reading, Writing, Math, Science, Creativity"
Tero Toivanen

Autism disorders might be reversible. | - I Teach Autism.com - - 0 views

www.iteachautism.com/...-or-disorder-may-be-reversible

autism fever epigenetics locus coeruleus brain neurobiology LC-NA system theory Albert Einstein College

shared by Tero Toivanen on 08 Jun 09 - Cached
  • Scientists at Albert Einstein College of Medicine of Yeshiva University have proposed a sweeping new theory of autism that suggests that the brains of people with autism are structurally normal but dysregulated, meaning symptoms of the disorder might be reversible.
  • The central tenet of the theory, published in the March issue of Brain Research Reviews, is that autism is a developmental disorder caused by impaired regulation of the locus coeruleus, a bundle of neurons in the brain stem that processes sensory signals from all areas of the body.
  • The new theory stems from decades of anecdotal observations that some autistic children seem to improve when they have a fever, only to regress when the fever ebbs.
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  • Einstein researchers contend that scientific evidence directly points to the locus coeruleus–noradrenergic (LC-NA) system as being involved in autism. “The LC-NA system is the only brain system involved both in producing fever and controlling behavior,” says co-author Dominick P. Purpura, M.D., dean emeritus and distinguished professor of neuroscience at Einstein.
  • The locus coeruleus has widespread connections to brain regions that process sensory information.
  • It is also involved in a variety of complex behaviors, such as attentional focusing (the ability to concentrate attention on environmental cues relevant to the task in hand, or to switch attention from one task to another).
  • “What is unique about the locus coeruleus is that it activates almost all higher-order brain centers that are involved in complex cognitive tasks,” says Dr. Mehler.
  • Drs. Purpura and Mehler hypothesize that in autism, the LC-NA system is dysregulated by the interplay of environment, genetic, and epigenetic factors (chemical substances both within as well as outside the genome that regulate the expression of genes). They believe that stress plays a central role in dysregulation of the LC-NA system, especially in the latter stages of prenatal development when the fetal brain is particularly vulnerable.
  • Drs. Purpura and Mehler believe that, in autistic children, fever stimulates the LC-NA system, temporarily restoring its normal regulatory function.
  • the future of autism treatment probably lies in drugs that selectively target certain types of noradrenergic brain receptors or, more likely, in epigenetic therapies targeting genes of the LC-NA system.
  • “You can’t take a complex neuropsychiatric disease that has escaped our understanding for 50 years and in one fell swoop have a therapy that is going to reverse it — that’s folly. On the other hand, we now have clues to the neurobiology, the genetics, and the epigenetics of autism. To move forward, we need to invest more money in basic science to look at the genome and the epigenome in a more focused way.”
  • Tero Toivanen on 08 Jun 09
     
    Scientists at Albert Einstein College of Medicine of Yeshiva University have proposed a sweeping new theory of autism that suggests that the brains of people with autism are structurally normal but dysregulated, meaning symptoms of the disorder might be reversible.
Tero Toivanen

How to unleash your brain's inner genius - life - 03 June 2009 - New Scientist - 0 views

www.newscientist.com/...-your-brains-inner-genius.html

savant autism brain genius talent

shared by Tero Toivanen on 04 Jun 09 - Cached
  • A flurry of research published earlier this year in the journal Philosophical Transactions of the Royal Society B paints a very different picture. It turns out that these skills are far more common than previously thought. They may even arise from traits found in the general population, implying that savants are not fundamentally different from the rest of us. What's more, these skills may only blossom after years of obsessive practice, raising the question of whether many more people might cultivate similar skills, if only they had the motivation.
  • One of the biggest clues to the origins of savant talent lies in the fact that savants are far more common within the autistic population than among people with other mental difficulties.
  • Previously, about 1 in 10 people with autism were thought to have a special ability but in April, Patricia Howlin at the Institute of Psychiatry at King's College London found a much higher figure in the autistic adults she surveyed for savant skills or an exceptional cognitive ability.
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  • Savant skills included more fully developed talents, such as being able to name the elevation of both the sun and the moon at any time of day, on any specified date; being able to name the day of the week for any date in the distant past or future (a talent known as calendrical calculation) and perfect pitch. Importantly, the abilities and the skills had to be exceptional by the standards of the general population, but also well above the individual's overall level of ability. In total, roughly 30 per cent had some kind of special ability (Philosophical Transactions of the Royal Society B, vol 364, p 1359).
  • For musical savants like Paravicini, Happé suggests that a bias towards small details might have led their developing brains to focus more on the exact notes than the overall melody, leading to perfect pitch and an exceptional musical memory. In art, a focus on small regions of a picture could lead to accurate perspective drawing.
  • Most people find this harder when they are shown an unsegmented version of the pattern versus a segmented one, but people with autism don't have this preference, demonstrating their skill at seeing a whole in terms of its parts even if there are no obvious dividing lines (see diagram). "It shows they are able to do the segmentation in their minds," says Winner. The precocious realists did not have this preference either, indicating a talent for realistic drawing may arise from this isolated trait commonly found in autism (Philosophical Transactions of the Royal Society B, vol 364, p 1449).
  • Although these results help to pinpoint exactly what it is about autism that predisposes people to talent, it's still not clear why an eye for detail is more common in autistic people in the first place. Clues might lie in the work of Simon Baron-Cohen from the University of Cambridge, which suggests that people with autism are "hypersensitive" to sensory information
  • Daniel Tammet, a prodigious savant who has memorised pi to 22,514 digits, believes his own talents have arisen from a special ability to connect different pieces of information together. "Savant abilities are linked to a highly associative type of thinking, an extreme form of a kind that everyone does - examples would include daydreaming, puns and the use of metaphors," he says.
  • The few studies of savant brains certainly suggest they are physically different from the average brain. For example, when Happé and Wallace studied the brain of a savant gifted at art, calendrical calculation and memory, they found his cortex was thicker in the areas associated with visuospatial processing and calculation and thinner in other regions associated with social cognition, compared with people who were neither savants nor autistic. But whether these differences were innate or grew with lifelong practice was still unclear.
  • The answer to that question may come from an unlikely source - a study of London taxi drivers who have acquired an encyclopedic memory of the streets of London known as "the Knowledge". Given that taxi drivers must remember the layout of 25,000 streets and the location of thousands of places of interest, and retrieve the information instantaneously, some researchers like Happé believe the Knowledge qualifies as a savant-like skill.
  • Eleanor Maguire and colleagues at the Institute of Neurology at University College London and colleagues found that drivers with the Knowledge have a bigger rear hippocampus than bus drivers and adults who do not drive taxis. In addition, the hippocampus appears to be larger the longer a taxi driver has been working, and shrinks once they retire (Philosophical Transactions of the Royal Society B, DOI: 10.1098/rstb.2008.0288).
  • In fact, it seems the remaining mystery is not so much how savants achieve their talents, but what drives them in the first place. "Motivation is a big unknown," says Wallace. "It's an enormous driving force in giftedness and in savants, but we don't know a lot about it."
  • One person who has something of an inside view on what contributes to savant ability is Paravicini's mentor, Adam Ockelford, a professor of music at Roehampton University in London who has watched Paravicini's talent blossom since the age of 4. When they first met, Paravicini was entirely self-taught and bashed at his plastic keyboard with his fists and elbows to reproduce the sounds he was hearing. It was only after years of practice that his technical skills developed.
  • But as researchers like Wallace have suggested, Paravicini seemed motivated way beyond the average music student. In fact, he seemed to be playing as if his life depended on it, and Ockelford thinks it's this that truly sets savants apart from their peers. "The survival instinct gets turned with extraordinary force into something else - in Derek's case music," says Ockelford. "When people see Derek, they think it is amazing, almost religious. But to me, it's mainly just hard work."
  • Tero Toivanen on 04 Jun 09
     
    But now researchers are beginning to unearth clues as to how savants' formidable brains work, and that in turn is changing our view of what it means to be a savant.
Patti Porto

National Professional Development Center on ASD - 0 views

autismpdc.fpg.unc.edu

asd autism

shared by Patti Porto on 18 Oct 12 - Cached
  • Patti Porto on 18 Oct 12
     
    "The National Professional Development Center on Autism Spectrum Disorders is a multi-university center to promote the use of evidence-based practice for children and adolescents with autism spectrum disorders."
Tero Toivanen

Neuronal Circuits In Autism Can Be Reversed - 0 views

www.medicalnewstoday.com/...250295.php

autism research

shared by Tero Toivanen on 17 Sep 12 - No Cached
  • When the production of neuroligin-3 in the mice was reactivated, the nerve cells reduced the production of the glutamate receptors to a normal level and the structural defects in the brain typical for autism were gone. Consequently, these glutamate receptors could be targeted in the development of drugs that could stop autism from developing or even reverse it.
  • Tero Toivanen on 17 Sep 12
     
    "A specific dysfunction in neuronal circuits has been identified, by Professors Peter Scheiffele and Kaspar Vogt at the Biozentrum of the University of Basel, that results from autism. The researchers also discovered a way to reverse these neuronal changes. They believe that their findings, published in the journal Science, will have a great effect in drug development for treating autism."
Tero Toivanen

Interactive Multimedia Technology: Interactive Visual Supports for Children with Autism... - 2 views

interactivemultimediatechnology.blogspot.com/...ctive-visual-supports-for.html

autism Technology support autism spectrum disorders interactive technology

shared by Tero Toivanen on 07 Feb 10 - Cached
  • Tero Toivanen on 07 Feb 10
     
    Here is an update about the work of Gillian Hayes, an assistant professor at the School of Informatics at the University of California at Irvine. Much of her work focuses on technology that supports young people with autism spectrum disorders.
Tero Toivanen

The Mirror Neuron Revolution: Explaining What Makes Humans Social: Scientific American - 0 views

www.sciam.com/article.cfm

autism mirror neuron social cognition mental disorder

shared by Tero Toivanen on 18 Apr 09 - Cached
  • In recent years, Iacoboni has shown that mirror neurons may be an important element of social cognition and that defects in the mirror neuron system may underlie a variety of mental disorders, such as autism.
  • Mirror neurons are the only brain cells we know of that seem specialized to code the actions of other people and also our own actions. They are obviously essential brain cells for social interactions. Without them, we would likely be blind to the actions, intentions and emotions of other people.
  • The way mirror neurons likely let us understand others is by providing some kind of inner imitation of the actions of other people, which in turn leads us to “simulate” the intentions and emotions associated with those actions. When I see you smiling, my mirror neurons for smiling fire up, too, initiating a cascade of neural activity that evokes the feeling we typically associate with a smile.
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  • In 2006 your lab published a paper in Nature Neuroscience linking a mirror neuron dysfunction to autism. How might reduced mirror neuron activity explain the symptoms of autism?
  • Reduced mirror neuron activity obviously weakens the ability of these patients to experience immediately and effortlessly what other people are experiencing, thus making social interactions particularly difficult for these patients. Patients with autism have also often motor problems and language problems. It turns out that a deficit in mirror neurons can in principle explain also these other major symptoms. The motor deficits in autism can be easily explained because mirror neurons are just special types of premotor neurons, brain cells essential for planning and selecting actions. It has been also hypothesized that mirror neurons may be important in language evolution and language acquisition.
  • Thus, a deficit in mirror neurons can in principle account for three major symptoms of autism, the social, motor and language problems.
  • There is convincing behavioral evidence linking media violence with imitative violence. Mirror neurons provide a plausible neurobiological mechanism that explains why being exposed to media violence leads to imitative violence.
  • I think there are two key points to keep in mind. The first one is the one we started with: mirror neurons are brain cells specialized for actions. They are obviously critical cells for social interactions but they can’t explain non-social cognition. The second point to keep in mind is that every brain cell and every neural system does not operate in a vacuum. Everything in the brain is interconnected, so that the activity of each cell reflects the dynamic interactions with other brain cells and other neural systems.
  • Tero Toivanen on 18 Apr 09
     
    In recent years, Marco Iacoboni, a neuroscientist at the University of California at Los Angeles, has shown that mirror neurons may be an important element of social cognition and that defects in the mirror neuron system may underlie a variety of mental disorders, such as autism.
Tero Toivanen

facilitated communication - The Skeptic's Dictionary - Skepdic.com - 0 views

skepdic.com/facilcom.html

skepdic facilitated communication autism FC

shared by Tero Toivanen on 26 Mar 09 - Cached
  • The American Psychological Association has issued a position paper on FC, stating that "Studies have repeatedly demonstrated that facilitated communication is not a scientifically valid technique for individuals with autism or mental retardation" and describing FC as "a controversial and unproved communicative procedure with no scientifically demonstrated support for its efficacy."
  • Frontline Program on facilitated communication:
    • Tero Toivanen
      Tero Toivanen on 26 Mar 09
       
      Here is the video about Facilitated Communication (FC). If you have something to do with FC, I think you should watch it.
  • Parents are grateful to discover that their child is not hopelessly retarded but is either normal or above normal in intelligence. FC allows their children to demonstrate their intelligence; it provides them with a vehicle heretofore denied them.
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  • Facilitated Communication therapy began in Australia with Rosemary Crossley. The center for FC in the United States is Syracuse University, which houses the Facilitated Communication Institute (FCI) in their School of Education.
  • A very damaging, detailed criticism was presented on PBS's "Frontline", October 19, 1993. The program was repeated December 17, 1996, and added that since the first showing, Syracuse University has claimed to have done three studies which verify the reality and effectiveness of FC, while thirty other studies done elsewhere have concluded just the opposite.
  • Furthermore, FC clients routinely use a flat board or keyboard, over which the facilitator holds their pointing finger. Even the most expert typist could not routinely hit correct letters without some reference as a starting point.
  • Facilitators routinely look at the keyboard; clients do not. The messages' basic coherence indicates that they most probably are produced by someone who is looking at the keyboard.
  • Anyone familiar with Helen Keller, Stephen Hawking or Christy Brown knows that blindness, deafness, cerebral palsy, multiple sclerosis, amyotrophic lateral sclerosis (ALS), or physical or neurological disorders, do not necessarily affect the intellect. There is no necessary connection between a physical handicap and a mental handicap. We also know that such people often require an assistant to facilitate their communication. But what facilitators do to help the likes of a Hawking or a Brown is a far cry from what those in the facilitated communication business are doing.
  • But the vast majority of FC clients apparently are mentally retarded or autistic. Their facilitators appear to be reporting their own thoughts, not their patient's thoughts. Interestingly, the facilitators are genuinely shocked when they discover that they are not really communicating their patient's thoughts. Their reaction is similar to that of dowsers and others with "special powers" who, when tested under controlled conditions, find they don't have any special powers at all.
  • It is interesting that the parents and other loved ones who have been bonding with the patient for years are unable to be facilitators with their own children.
  • And when the kind strangers and their patients are put to the test, they generally fail. We are told that is because the conditions made them nervous. These ad hoc excuses sound familiar; they sound like the complaints of parapsychologists.
  • Skeptics think the evidence is in and FC is a delusion for the most part. It is also a dangerous delusion. Critics have noted a similarity between FC therapy and repressed memory therapy: patients are accusing their parents and others of having sexually abused them. Facilitators are taught that something like 13% of their clients have been sexually abused. This information may unconsciously influence their work.
  • Tero Toivanen on 26 Mar 09
     
    You find here a very about Important Video about Facilitated Communication (FC). The American Psychological Association has issued a position paper on FC, stating that "Studies have repeatedly demonstrated that facilitated communication is not a scientifically valid technique for individuals with autism or mental retardation" and describing FC as "a controversial and unproved communicative procedure with no scientifically demonstrated support for its efficacy."
Tero Toivanen

Toddler brain difference linked to autism - CNN.com - 0 views

edition.cnn.com/...autism.brain.amygdala

autism research amygdala

shared by Tero Toivanen on 09 May 09 - Cached
  • Tero Toivanen on 09 May 09
     
    The size of a specific part of the brain may help experts pinpoint when autism could first develop, University of North Carolina researchers report.
J B

British DVD Takes Aim At Autism: Cartoons Focus on Facial Expressions - washingtonpost.com - 0 views

www.washingtonpost.com/...AR2009033002144.html

autism emotions

shared by J B on 04 Apr 09 - Cached
  • J B on 04 Apr 09
     
    Happy, worried, surprised, ashamed: Children with autism can find it difficult to discern from facial expressions how another person is feeling. A team of researchers at Britain's Cambridge University has created an animated DVD called "The Transporters" to help children with autism learn this...
Tero Toivanen

An Apple for the Students | By Marcia Kaye | University of Toronto Magazine - 3 views

www.magazine.utoronto.ca/...ildren-autism-ipad-marcia-kaye

autism students special needs ipad ipads

shared by Tero Toivanen on 30 Apr 12 - No Cached
  • The two-year study, which ended last December, found that within six weeks the devices boosted kids’ attention spans, raised their ability to identify pictured objects by 45 to 60 per cent, and improved communication skills in these mostly nonverbal children by 20 per cent.
  • A surprising bonus: students who had never been sociable were suddenly requesting an iPad to initiate an activity with another student.
  • McEwen suggests that the devices’ appeal may lie in their multisensory nature, with images and sound – and vibration (thanks to the addition of a downloadable app). She adds that the device’s voice app, which is always calm and unemotional, appeals to those who thrive on consistency, including many children with ASD.
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  • One boy in kindergarten who had always ignored green “yes” and red “no” boxes on paper responded instantly to the identical boxes on the screen.
  • The iPad’s larger screen is better suited to children with vision or fine-motor challenges, such as the blind six-year-old in a wheelchair who delights in moving his arm across the tablet to create his own music.
  • Tero Toivanen on 30 Apr 12
     
    Autistic children develop better communications skills when using iPads, researcher finds
Tero Toivanen

Autism finding could lead to simple urine test for the condition - 0 views

www.physorg.com/news194764448.html

autism urine test research bacteria guts gut bacteria gastrointestinal

shared by Tero Toivanen on 03 Jun 10 - Cached
  • The researchers behind the study, from Imperial College London and the University of South Australia, suggest that their findings could ultimately lead to a simple urine test to determine whether or not a young child has autism.
  • People with autism are also known to suffer from gastrointestinal disorders and they have a different makeup of bacteria in their guts from non-autistic people.
  • Today's research shows that it is possible to distinguish between autistic and non-autistic children by looking at the by-products of gut bacteria and the body's metabolic processes in the children's urine. The exact biological significance of gastrointestinal disorders in the development of autism is unknown.
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  • The distinctive urinary metabolic fingerprint for autism identified in today's study could form the basis of a non-invasive test that might help diagnose autism earlier. This would enable autistic children to receive assistance, such as advanced behavioural therapy, earlier in their development than is currently possible.
  • The researchers suggest that their new understanding of the makeup of bacteria in autistic children's guts could also help scientists to develop treatments to tackle autistic people's gastrointestinal problems.
  • Professor Jeremy Nicholson, the corresponding author of the study, who is the Head of the Department of Surgery and Cancer at Imperial College London, said: "Autism is a condition that affects a person's social skills, so at first it might seem strange that there's a relationship between autism and what's happening in someone's gut. However, your metabolism and the makeup of your gut bacteria reflect all sorts of things, including your lifestyle and your genes. Autism affects many different parts of a person's system and our study shows that you can see how it disrupts their system by looking at their metabolism and their gut bacteria.
  • We hope our findings might be the first step towards creating a simple urine test to diagnose autism at a really young age
  • A urine test might enable professionals to quickly identify children with autism and help them early on," he added.
  • The researchers reached their conclusions by using H NMR Spectroscopy to analyse the urine of three groups of children aged between 3 and 9: 39 children who had previously been diagnosed with autism, 28 non-autistic siblings of children with autism, and 34 children who did not have autism who did not have an autistic sibling. They found that each of the three groups had a distinct chemical fingerprint. Non-autistic children with autistic siblings had a different chemical fingerprint than those without any autistic siblings, and autistic children had a different chemical fingerprint than the other two groups.
  • Tero Toivanen on 03 Jun 10
     
    This is interesting finding. Hope it will give results!
Tero Toivanen

Non-Verbal Autistics: Why No Words? - 1 views

autism.about.com/...bal-autistics-why-no-words.htm

autism non-verbal autistics Lisa Jo Rudy speak words apraxia echolalia

shared by Tero Toivanen on 10 May 10 - Cached
  • To be honest, I had assumed that those people who do not speak - but DO communicate - have physical issues with forming words.  After all, I reasoned, if a person wants to communicate but doesn't speak, it must be because speech is just too difficult. But it turns out that I may be wrong.  In fact, according to a top researcher in autism and communication (Dr. Helen Tager-Flusberg, PhD of Boston University), "...the short answer is that we really don't know why some children with ASD don't learn to speak at all."
    • Tero Toivanen
      Tero Toivanen on 10 May 10
       
      This is the big question!
Tero Toivanen

Autism and early oxygen deprivation | On the Brain by Dr. Mike Merzenich,Ph.D. - 0 views

merzenich.positscience.com/?p=181

autism umbilical cord oxygen deprivation

shared by Tero Toivanen on 04 Jun 09 - Cached
  • we had dismissed perinatal anoxia as a likely factor contributing to autism’s apparent rise because we could not see how ITS incidence could be growing over the past several decades.
  • it has recently been argued that the especially high susceptibility of the highly metabolically active auditory brainstem to brief periods of anoxia that we and others have documented comes into play in the few to many tens of seconds of oxygen starvation that can stem from very rapid umbilical cord clamping— practices for which have changed (more rapid clamping has been adopted) over the past several decades.
  • earlier clamping of the umbilical cord became the standard of care world-wide beginning in the mid 1980’s, i.e., corresponding to the epoch in which scientists and educators began to first recognize an increase in autism incidence.
  • ...3 more annotations...
  • Why change an age-old practice invited by Mother Nature or the Creator of the Universe, when it is so obviously a product of 80 million years of natural selection?! Why race to get that clamp on the umbilical cord well before blood flow in the cord stopped on its own?
  • Interestingly, the obstetrics profession itself seems to be questioning the adoption of use of early-clamping procedures, as several important meta-analyses have now shown that late cord clamping (after the umbilical flow has stopped on its own = Nature’s Way) is (big surprise) beneficial to the newborn, with significant positive benefits for late (more natural) cord clamping recorded (in ferritin, which translates to hemoglobin which translates to oxygenation) up to 6 months later (e.g., see Hutton & Hassan, JAMA 297:1241).
  • It shall be interesting to see whether or not changes in these practices back to the “old way” results in a reduction in autism incidence. Stay tuned — because it looks like the experiment is now underway!
  • Tero Toivanen on 04 Jun 09
     
    Earlier clamping of the umbilical cord became the standard of care world-wide beginning in the mid 1980's, i.e., corresponding to the epoch in which scientists and educators began to first recognize an increase in autism incidence.
Tero Toivanen

News from the Associated Press - newsjournalonline.com - 0 views

hosted.ap.org/...US_MED_AUTISM_RECOVERY

autism research behavioral therapy recover

shared by Tero Toivanen on 09 May 09 - Cached
  • Leo Lytel was diagnosed with autism as a toddler. But by age 9 he had overcome the disorder. His progress is part of a growing body of research that suggests at least 10 percent of children with autism can "recover" from it - most of them after undergoing years of intensive behavioral therapy.
  • She presented research this week at an autism conference in Chicago that included 20 children who, according to rigorous analysis, got a correct diagnosis but years later were no longer considered autistic.
  • Skeptics question the phenomenon, but University of Connecticut psychology professor Deborah Fein is among those convinced it's real.
  • ...10 more annotations...
  • Previous studies have suggested between 3 percent and 25 percent of autistic kids recover. Fein says her studies have shown the range is 10 percent to 20 percent.
  • But even after lots of therapy - often carefully designed educational and social activities with rewards - most autistic children remain autistic. Recovery is "not a realistic expectation for the majority of kids," but parents should know it can happen, Fein said.
  • The children in Fein's study, which is still ongoing, were diagnosed by an autism specialist before age 5 but no longer meet diagnostic criteria for autism. The initial diagnoses were verified through early medical records.
  • The researchers are also doing imaging tests to see if the recovered kids' brains look more like those of autistic or nonautistic children.
  • Imaging scans also are being done to examine brain function in formerly autistic kids.
  • Results from those tests are still being analyzed.
  • Most of the formerly autistic kids got long-term behavior treatment soon after diagnosis, in some cases for 30 or 40 hours weekly.
  • Many also have above-average IQs and had been diagnosed with relatively mild cases of autism. At age 2, many were within the normal range for motor development, able to walk, climb and hold a pencil.
  • Significant improvement suggesting recovery was evident by around age 7 in most cases, Fein said.
  • None of the children has shown any sign of relapse. But nearly three-fourths of the formerly autistic kids have had other disorders, including attention-deficit problems, tics and phobias; eight still are affected.
  • Tero Toivanen on 09 May 09
     
    Leo Lytel was diagnosed with autism as a toddler. But by age 9 he had overcome the disorder. His progress is part of a growing body of research that suggests at least 10 percent of children with autism can "recover" from it - most of them after undergoing years of intensive behavioral therapy.
Tero Toivanen

NeuroLogica Blog » The Genetics of Autism - 0 views

www.theness.com/neurologicablog

autism genetics

shared by Tero Toivanen on 03 May 09 - Cached
  • What this means is that there is likely to be a complex set of many factors that contribute to ASD - not one single cause.
  • The same exact situation is true for other entities, like schizophrenia and attention deficit disorder (ADD).
  • One difference, however, is that schizophrenia and ADD likely represent changes to particular parts of the brain, while autism is likely due to changes in the global architecture of the brain.
  • ...5 more annotations...
  • Getting back to the genetics of autism, current models are therefore consistent with what is being found when the genetics of autism is researched - researchers are finding many genes that predispose to autism in a subset of cases but no single or simple universal cause. At present, 133 different gene variants have been linked to autism.
  • This new research, conducted by Dr. Hakon Hakonarson of the Children’s Hospital of Philadelphia, is a genome wide analysis involving about 10,000 individuals.
  • The results are especially significant because the variants lie between two genes, called CDH9 and CDH10, which are known to play an important role in forming nerve connections in the brain.
  • The gene variants that correlated with ASD are for proteins that are involved in the process of neurons forming connections with each other. There is already other lines of evidence that suggest what is different in ASD brains is a decrease in the amount of interconnectedness and communication among neurons. It is therefore likely no coincidence that this study found genetic correlations for proteins involved with neuronal connections.
  • This also is compatible with the finding that many separate genes are potentially involved with ASD - for there are many separate genes and processes involved with forming and maintaining neuronal connections.
  • Tero Toivanen on 03 May 09
     
    A new genome-wide analysis of families with autism has found significant gene associations, adding to the growing evidence for strong genetic contribution to autism.
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