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Tero Toivanen

Autism Research Blog: Translating Autism: Amygdala, autism and clinical impairment: Whe... - 0 views

www.translatingautism.com/...m-and-clinical-impairment.html

amygdala autism high functioning autism Asperger's Disorder asperger

shared by Tero Toivanen on 03 Mar 09 - No Cached
  • The amygala serves a critical function in emotion recognition and processing, and thus it has been implicated in the neurophysiology of autism. For example, individuals with autism have been found to display atypical amygdala growth processes from childhood into adolescence (see for example Nacewiz et al., 2006. Archives of General Psychiatry, 63,12).
  • The Amygdale's bilateral biochemical functioning was obtained via magnetic resonance spectroscopy. Four metabolites were measured: N-acetyl aspartate (NAA), creatine/Phosphocreatine (Cre), choline (Cho), and myoinositol (ml).
  • The authors did not find any differences in the concentrations of any of the metabolites when comparing the HFA and the control groups
  • ...4 more annotations...
  • However, among the individuals with HFA, NAA was significantly associated with communication impairments, as measured by the ADI. In addition, Cre and NAA were associated with restrictive interests, and Cre alone was associated with social difficulties. The results therefore, indicate that those with the lowest concentrations of these metabolites tended to have more severe clinical symptoms as reported by the ADI.
  • The results of this study provide support for the need to conduct examinations that go beyond simple group comparisons.
  • key metabolites, while observed at normative levels, play a key role in the clinical presentation of the disorder.
  • presence of normative functioning in a particular domain or brain process (when compared to typical peers) does not necessarily indicate that such domain is not implicated in the phenomenology of the condition.
  • Tero Toivanen on 03 Mar 09
     
    Amygdala, autism and clinical impairment: When group comparisons are not enough. The results of this study provide support for the need to conduct examinations that go beyond simple group comparisons. In this case, the authors found no differences in any of the metabolites between the two groups, which could easily lead one to conclude that such metabolites may not play a role in autism. Yet, the results were strong in indicating that key metabolites, while observed at normative levels, play a key role in the clinical presentation of the disorder.
Tero Toivanen

Early intervention for toddlers with autism highly effective, study finds - 1 views

www.physorg.com/news178781035.html

autism toddlers study IQ language ability social interaction

shared by Tero Toivanen on 17 Dec 09 - Cached
  • The study, published online today in the journal Pediatrics, examined an intervention called the Early Start Denver Model, which combines applied behavioral analysis (ABA) teaching methods with developmental 'relationship-based' approaches.
  • The five-year study took place at the University of Washington (UW) in Seattle and was led by Dawson, then a professor of psychology and director of the university's Autism Center, in partnership with Rogers. It involved therapy for 48 diverse, 18- to 30-month-old children with autism and no other health problems.
  • At the conclusion of the study, the IQs of the children in the intervention group had improved by an average of approximately 18 points, compared to a little more than four points in the comparison group. The intervention group also had a nearly 18-point improvement in receptive language (listening and understanding) compared to approximately 10 points in the comparison group. Seven of the children in the intervention group had enough improvement in overall skills to warrant a change in diagnosis from autism to the milder condition known as 'pervasive developmental disorder not otherwise specified,' or PDD-NOS. Only one child in the community-based intervention group had an improved diagnosis.
  • ...2 more annotations...
  • In this study, the intervention was provided in a toddler's natural environment (their home) and delivered by trained therapists and parents who received instruction and training as part of the model.
  • Parents are taught strategies for capturing their children's attention and promoting communication. By using these strategies throughout the day, the children were offered many opportunities to learn to interact with others.
  • Tero Toivanen on 17 Dec 09
     
    A novel early intervention program for very young children with autism - some as young as 18 months - is effective for improving IQ, language ability, and social interaction, a comprehensive new study has found.
Graeme Wadlow

Cultural Confusions Show that Facial Expressions Are Not Universal - 0 views

www.cell.com/...S0960982209014778

Adult; Confusion; Cross-Cultural Comparison; Cultural Characteristics; Culture; Emotions; Eye Movements; universal

shared by Graeme Wadlow on 04 Jan 12 - No Cached
  • Graeme Wadlow on 04 Jan 12
     
    Current Biology - Cultural Confusions Show that Facial Expressions Are Not Universal
Tero Toivanen

Asperger Square 8: Judging a Book by its Cover - 0 views

aspergersquare8.blogspot.com/...judging-book-by-its-cover.html

asperger

shared by Tero Toivanen on 08 Mar 09 - Cached
  • I've heard too many cracks from "helpful" people, telling people not to call us autistics, or autistic people, but "people with autism," with the reasoning that "You don't call somebody a cancer patient, you call them a person with cancer." It makes me a little more sad and angry every time I see that comparison, and this... is the worst thing so far, in that vein.
    • Tero Toivanen
      Tero Toivanen on 08 Mar 09
       
      How to call this people?
  • Tero Toivanen on 08 Mar 09
     
    Judging a Book by its Cover
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