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nehaha00

Man Ravaging Lyme Disease Eludes Doctors For a Year - 0 views

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    This article didn't necessary discuss what caused Lyme disease, but rather it talked about how the modern Lyme disease test is inefficient in determining whether a patient truly has Lyme disease. See, the concept is that the Lyme disease is caused by the bacterium Borrelia burgdorferi. So, natuarally the Lyme disease test is designed to only look for said bacterium, but the problem is that in Europe Lyme disease is commonly caused by the bacterium Borrelia garinii which means that if one were to contract Lyme disease from the bacterium Borrelia garinii and get tested for Lyme disease in America they would get a negative result despite actually having the disease. European screening for Lyme disease is called the c-6 based ELISA test and it can detect approximetly 18 different species of Borrelia, but the CDC reports that this test isn't used in America, and this neglect can prove detrimental for many who have Lyme disease. As a result of America's dreadful Lyme disease test many companies have developed their own tests, but none of those have shown to be any more reliable than the one recommended by the CDC. Thusly showing that America should improve its Lyme disease test.
Nicholas Scholz

Parkinsons DIsease - NIH - 0 views

  • Parkinson's disease (PD) belongs to a group of conditions called motor system disorders, which are the result of the loss of dopamine-producing brain cells
  • symptoms of PD are tremor, or trembling in hands
  • bradykinesia, or slowness of movemen
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  • As these symptoms become more pronounced, patients may have difficulty walking, talking, or completing other simple tasks
  • difficulty in swallowing
  • At present, there is no cure for PD
  • and progressive
  • A therapy called deep brain stimulation (DBS) has now been approved by the U.S. Food and Drug Administration
  • Usually, patients are given levodopa
  • movements called dyskinesias that are a common side effect of levodopa
  • PD is both chronic
  • In some cases, surgery may be appropriate if the disease doesn't respond to drugs
  • No one can predict which symptoms will affect an individual patient, and the intensity of the symptoms also varies from person to person.
  • PD research in laboratories at the National Institutes of Health (NIH)
  • Scientists looking for the cause of PD
  • develop new protective drugs that can delay, prevent, or reverse the disease.
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    This article pertains to the neurological disorder, Parkinson's Disease (PD). PD is known to reduce motor system function due to the loss of dopamine-producing brain cells. Most symptoms related to PD include tremors, trembling, and slowness of movement (bradykinesia). As the disease progresses these tremors begin to effect daily activities like chewing and speaking. Unfortunately there is no cure for Parkinson's Disease. The most common treatment for PD is the use of medications such as levodopa. Due to complications with current medications other treatments like deep brain stimulation and surgery are commonly used. Parkinson's Disease is both chronic and progressive. Tremors and other symptoms will occur for long periods of time and possibly grow worse. Patients with PD experience varying symptoms and intensities. Current research being done in response to Parkinson's is being conducted at the National Institute of Health (NIH) and elsewhere. Current topics of research include discovering the cause of PD, and the development of protective drugs needed to delay, prevent, and even reverse the disease.
Nicholas Scholz

Multiple Sclerosis - 0 views

  • Multiple sclerosis (or MS) is a chronic, often disabling disease that attacks the central nervous system (CNS)
  • MS is a disease that involves an immune system attack against the central nervous system (brain, spinal cord, and optic nerves)
  • Although MS is thought by some scientists to be an autoimmine disease, others disagree strongly because the specific target of the immune attack in MS has not yet been identified. For this reason, MS is referred to as an immune-mediated disease.
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  • As part of the immune attack on the central nervous system, myelin (the fatty substance that surrounds and protects the nerve fibers in the central nervous system) is damaged, as well as the nerve fibers themselves
  • The damaged myelin forms scar tissue (sclerosis
  • Relapsing-Remitting MS
  • People with this type of MS experience clearly defined attacks of worsening neurologic function. These attacks—which are called relapses, flare-ups, or exacerbations —are followed by partial or complete recovery periods (remissions
  • Primary-Progressive MS
  • This disease course is characterized by slowly worsening neurologic function from the beginning—with no distinct relapses or remissions
  • Secondary-Progressive MS
  • Following an initial period of relapsing-remitting MS, many people develop a secondary-progressive disease course in which the disease worsens more steadily, with or without occasional flare-ups, minor recoveries (remissions), or plateaus
  • Progressive-Relapsing MS
  • In this relatively rare course of MS (5%), people experience steadily worsening disease from the beginning, but with clear attacks of worsening neurologic function along the way
  • but the disease continues to progress without remissions.
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    Multiple sclerosis has been associated with attacks against the central nervous system. The immune system has been identified to targeting organs such as the brain, spinal cord, and optic nerves. It is known as an immune - mediated disease because there is no specific target that has been identified. The attacks by the immune system often damage myelin and create scarred tissue (sclerosis). Patients with multiple sclerosis could experience one of four courses identified with the disease. One course is the Relapsing-Remitting MS. In this course the patient experiences a severe attack on the CNS followed by remissions. The second course is known as the Primary-Progressive MS. In this course the central nervous system slowly deteriorates without any relapses or remissions. Another course of MS is the Secondary-Progressive MS. This form of MS generally follows the relapsing-remitting form of MS and progressively worsens the CNS with or without remissions and plateaus. The most rare form of MS is perhaps the Progressive-Relapsing MS. In this course of MS, patients generally experience a progressive worsening of neurological function, without any remissions.  
Melissa Menghini

Vaccination Statistics - 0 views

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    Although popularized by the media as "healthy," vaccinations bring more harm to the human body then they do health. Multiple studies have found that those children injected with vaccinations actually caught more disease than those not vaccinated. Vaccinations are not guaranteed to work, and can actually cause severe complications. Few vaccinations have been successful; these effective immunizations protect against one disease, but increase risk of other viruses. Vaccines contain harmful ingredients that can cause cancers and leukemia, and are even linked to AIDS. Vaccines are also connected to brain damage, lowered IQ, ADD, learning disabilities, and autism. Vaccinations are composed of harmful ingredients, are illogically produced, and cause more diseases than they prevent.
Elizabeth Bundschuh

Introduction to Cancer Immunotherapy - 0 views

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    There is no "magic bullet" in the fight against cancer, but one step towards curing cancer is Immunotherapy. The generally accepted hypothesis is that the immune system is the best tool humans have for fighting disease. Immunotherapy is thought to be less toxic than current treatments, however it is rarely used by itself to treat cancer. There are limitations to the effectiveness of Immunotherapy; the normal immune system cannot sense tumor cells, the response from the immune system is not strong enough when the body does recognize tumor cells, and tumors can defend themselves. There are three types of Immunotherapy Passive, components of the immune system are engineered outside of the body to attack cancer cells; Active, stimulates the body's own immune system to fight cancer; and Combination, uses both passive and active activity. Passive Immunotherapy's use antibodies created outside of the body to provide immunity or help fight off a disease. One type of passive immunotherapy is Monoclonal antibody therapy (mAb), the most widely used form of immunotherapy. Active Immunotherapy work by stimulating the immune system to 'actively' respond to the disease. One type of active immunotherapy is Provenge, a therapeutic prostate cancer vaccine. Therapeutic cancer vaccines are given to patients with cancer to help stimulate the immune system to fight the cancer. Combination Therapy is still in clinical studies but is thought to have a greater potential than active or passive immunotherapy because it combines the activity of both therapies. Immunotherapy may not be the magic bullet to fighting cancer, but when used early and with other treatments it has proven effective.
Dakota Declue

Why don't we all get Alzheimer's disease? - 0 views

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    Alzheimer's disease is present in all humans but not everyone will develop the disease. A critical separation between a protein an d an enzyme that when combined triggers AD. There are two tell-tale signs of AD one being beta-amyloid or clumps of protein. Then there is tangles of proteins inside the neurons. Both proteins if aloud to combine we would say have AD. This findings are the base of the steps needed to further are research on AD.
Nicholas Scholz

Treatments and Medications Used for Patients with MS - 0 views

  • Corticosteroids are mainly used to reduce the inflammation that spikes during a relapse
  • Beta interferons. These types of drugs — such as Avonex, Betaseron, Extavia and Rebif — appear to slow the progress of multiple sclerosis, reduce the number of attacks and lessen the severity of attacks
  • (Copaxone). This medication may reduce the number of MS attacks
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  • (Tysabri). This medication may reduce the number of MS attacks by interfering with the movement of potentially damaging immune cells from your bloodstream to your brain and spinal cord.
  • Teriflunomide (Aubagio). This oral medication reduces attacks and lesions in people with MS.
  • Medications such as amantadine may help reduce fatigue due to multiple sclerosis.
  • Dalfampridine (Ampyra). This oral medication may improve walking speed in some people. The major side effect is seizures.
  • Muscle relaxants. If you have multiple sclerosis, you may experience painful or uncontrollable muscle stiffness or spasms, particularly in your legs. Muscle relaxants such as baclofen (Lioresal) and tizanidine (Zanaflex) may improve muscle spasticity
  • A physical or occupational therapist can teach you stretching and strengthening exercises and show you how to use devices that can make it easier to perform daily tasks.
  • For example, stem cell transplantation is being studied. In a stem cell transplant, doctors inject healthy stem cells into your body to replace diseased stem cells.
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    Though MS obviously has no cure there are plenty of procedures and medications that can be used to lessen the effects of the disease. Treating specific attacks reduces the damage to the myelin sheath. Two methods for controlling the attacks are plasma exchanges and corticosteroids. Another way to control the effects of MS is by slowing the progression of the disease. There are many different drugs that slow the rate of relapses some of which include Beta Interferons, Copaxone, Gilenya, and Tysabri. In addition to these medications, other strategies can be used to treat the symptoms, which include physical therapy and muscle relaxants. 
Elizabeth Bundschuh

Do we know what causes childhood leukemia? - 0 views

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    The cause of most cases of pediatric leukemia is not known, as most sufferers do not display any risk factors for the disease. However scientists have begun to understand how certain changes in DNA can cause leukemia. Cancer can be caused by mutation oncogenes, the genes that control when cells divide. A translocation between chromosomes 2 and 22 causes almost all cases of childhood chronic myeloid leukemia and childhood acute lymphocytic leukemia. Other genetic mutations can be inherited, however most of the mutations that cause leukemia develop after birth. Environmental factors, when combined with a genetic predisposition for leukemia, may trigger the disease. However the cause of most pediatric leukemia remains unknown.
Nicholas Scholz

Alzheimer's - Alzheimer's Association - 0 views

  • Alzheimer's is a type of dementia that causes problems with memory, thinking and behavior.
  • Alzheimer's disease accounts for 50 to 80 percent of dementia cases.
  • Up to 5 percent of people with the disease have early onset Alzheimer's
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  • Each nerve cell connects with many others to form communication networks
  • However, serious memory loss, confusion and other major changes in the way our minds work may be a sign that brain cells are failing.
  • Those with Alzheimer's live an average of eight years after their symptoms become noticeable
  • Keeping everything running requires coordination as well as large amounts of fuel and oxygen
  • Plaques are deposits of a protein fragment called beta-amyloid (BAY-tuh AM-uh-loyd) that build up in the spaces between nerve cells.
  • Tangles are twisted fibers of another protein called tau (rhymes with “wow”) that build up inside cells.
  • It's the destruction and death of nerve cells that causes memory failure, personality changes, problems carrying out daily activities and other symptoms of Alzheimer'
  • Ninety percent of what we know about Alzheimer's has been discovered in the last 15 years
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    Alzheimer's is actually a common form of dementia. Roughly 50-80 percent of patients with dementia are associated with Alzheimer's. Alzheimer's is considered a neurological disorder with loss of memory, thinking and behavioral function. Alzheimer's is common diagnosed in patients 65 and older with the exception of patients with Early-Onset Alzheimer's. Alzheimer's progressively worsens over time and commonly culminates in death 8 years after symptoms start to arrive. Again no cure has been found for alzheimer's, but certain medications are used to treat symptoms. A build-up of plaques and tangles in the brain is suspected to kill nerve cells and cause a loss of brain function. The loss of nerve cells causes gaps in the communication network and eventually causes a loss of function in those areas of the brain. Although scientists do not know their exact role in Alzheimer's, patients have been associated with an abundant amount of these abnormal structures.
Nicholas Scholz

Predicting the Spread of Brain Tumors Using Modern Day Biotechnology - 0 views

  • ISOpure uses a set of tumor expression profiles and a panel of healthy tissue expression profiles to generate a purified cancer profile for each tumor sample, and an estimate of the proportion of RNA originating from cancerous cells
  • samples pre-selected to have a high cancerous cell content using pathological estimates [20-23], thereby introducing variability into expression profiles that cannot be removed by current computational pre-processing methods
  • he challenge of computational purification is to decompose each tumor profile tn (a vector of length G) into its component cancer profile (the vector cn), and normal profile
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  • Computational purification of tumor expression profiles by ISOpure improves the accuracy of subsequent prognostic models for lung and prostate cancer by reducing inter-sample variation in the amount and type of gene expression signal in the tumor profile that is due to normal tissue contamination.
  • Our analysis demonstrated approximately 10% improvement in prediction of EPE when using ISOpure cancer profiles compared with the unpurified profiles.
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    Using the ISOpure computational purification tool, scientists and medical professionals can develop a prognosis and treatment plan for a certain cancer patients at a much quicker rate. The tool used in this process can help identify the cancerous tissue located in the organs and provide medical professionals further notice of the proportion of RNA originating from cancer cells allowing them to develop treatment plans ahead of time. ISOpure uses an algorithm which determines the proportion of RNA in the organ(s). The real challenges of developing these treatments is of course extracting a portion of tissue with both a normal profile and a cancer profile to predict the spread of the disease. After this portion of tissue has been extracted the ISOpure modeling can process the data using simple MATLAB software. The success of this computational tool is noted to improve the prediction of extra-prostatic-extension (EPE) by 10% in cancer profiles compared to the unpurified models. 
Dakota Declue

New plan of attack in cancer fight: Two-drug combination, under certain circumstances, ... - 0 views

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    Big new break through in the steps to curing cancer. Harvard Scientist have found a new drug combination that stops the growth of cancer and could be the answer to curing all cancer. Although the research isn't the cure from cancer its the start that is needed to find cancer. In order for the two drugs to work they must be given together. The two drug combination could possible cure most types of cancer but for some it could spell disaster.
nehaha00

A Sense of Time Requires a Sense of Space - 0 views

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    This article introduces an interesting notion, that in order to gauge time one must be aware of space.. After initially introducing the concept the author then describes a disease called left hemispatial neglect, which is when one is not able to remember the left half of something. The author cites how researchers then proceeded to test how people with left hemispatial neglect perceive time. The premise of the experiment is that in languages that write from left to right people visualize the past as being on the left of a timeline and the future on the right. So, in order to test the theory researchers had three groups of people one group spoke French and had left hemispatial neglect, the second group was composed of people who had had strokes but didn't have left hemi-spatial neglect, and the third group was composed of normal healthy people. In the experiment all three groups were given facts about a 40 year old man. Some of the facts were from 10 years ago when the man was 30 and some facts were from the future when the man would be 50. After each group was given this information they were quizzed on whether certain facts were from the past or the future, and the results showed that the group of people with left hemispatial neglect did worse than the other groups when remembering facts from 10 years ago (meaning the left side). Which lead researchers to the conclusion that time and space indeed are related.
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