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Melissa Menghini

Scientists grow teeth using stem cells from urine: study  - NY Daily News - 0 views

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    Chinese researches have discovered an ability to transform the cells found in urine into stem cells. Driving these scientists was the remarkable ability that stem cells possess: the ability to transform into other cells. These scientists actually transformed the cells from urine into stem cells, and used those stem cells to create human teeth in mice jawbones. This experiment did suffer several flaws, however. These teeth-like structures did contain a number of components that real teeth are composed of: enamel, dentin, and pulp. Even so, these teeth were only one-third as hard as human teeth. Additionally, this experiment resulted in 70% of the mice absent of teeth-like structures. Despite the flaws through the experiment, this discovery comes close to the regrowth of human features and gives hope to a possible future of regenerated human teeth. Better methods of obtaining cells with the ability to become stem cells exist, further giving the world of science hope in human body repair and regrowth. 
Melissa Menghini

Retina stem cell transplants restore sight to blind mice: study - NY Daily News - 0 views

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    British scientists have recently restored sight to blind mice by the use of stem cells from mice embryos. These stem cells were put into a lab dish; there, they separated into immature photo-receptors. These were then injected into the mice's retinas, and actually brought sight back into some of the blind. This successful experiment makes scientists hopeful that they can restore sight to blind humans in the future. Although these cells can become very beneficial, they can also turn cancerous. New scientific advancements have bettered the stem cell procedure, but problems with the process are still arising. 
Melissa Menghini

Scientists Use Stem Cells to Grow Mouse Inner Ears - 0 views

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    Recent stem cell research has enabled scientists to develop mice inner ears. This new discovery has high hopes to lead to future hearing restoration for humans, and reasoning on hear loss. This astonishing breakthrough is the result of the transformation of embryonic stem cells from mice into sensory epithelia. These epithelia contain hair cells, fragile cells that allow organisms to hear. This discovery is even more shocking through the impossibility for hair cells to grow once they have been destroyed. This exciting accomplishment allows for researchers to study hair cells, and their connection to hearing.
Melissa Menghini

Return of the mammoth? Dolly scientist says beast should be cloned | Fox News - 0 views

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    After the successful cloning of Dolly the sheep, scientists are hopeful to clone/bring back the mammoth from extinction. Notably well preserved blood in a recent finding of mammoth remains could lead to mammoth stem cells. With these stem cells and the use of elephant eggs to grow an embryo, a baby mammoth could be born. The stem cells could also form gametes, which, if from a female, could lead to both breeding and cloning mammoths. The method of cloning could be fairly similar to the process used to create Dolly the sheep. Although bringing back the mammoth would be beneficial for science, a debate exists arguing the issues. 
Melissa Menghini

Finger Regeneration: Stem Cells In Fingernails May Be Key To Regrowing Limbs, Scientist... - 0 views

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    A groundbreaking discovery in the mice ability to regenerate the tips of their digits leaves scientists hopeful for human regeneration in the future. Researches have found that as long as enough of the nail remains, any amputated digit tip has the capability to regrow. This process can be performed because of the colony of stem cells present under the nail base; however, this process can only proceed if enough of the nail epithelium remains on the amputated digit. The process that occurs after amputation starts with the activation of the Wnt pathway in the epithelium located underneath the remaining nail. After the nerves are attracted to the area, FGF2 (protein) directs the nerves into growing mesenchymal cells, cells used for regrowth. However, if too much of the digit is amputated, too much epithelium is lost, the Wnt pathway is never activated, and there is no regeneration. On another note, humans and mice are somewhat related to amphibians in their regeneration abilities; this further gives scientists hope for human regeneration in the future. The opposing side argues why humans differ from salamanders, and points out the flaws in this scientific discovery. 
Nicholas Scholz

Treatments and Medications Used for Patients with MS - 0 views

  • Corticosteroids are mainly used to reduce the inflammation that spikes during a relapse
  • Beta interferons. These types of drugs — such as Avonex, Betaseron, Extavia and Rebif — appear to slow the progress of multiple sclerosis, reduce the number of attacks and lessen the severity of attacks
  • (Copaxone). This medication may reduce the number of MS attacks
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  • (Tysabri). This medication may reduce the number of MS attacks by interfering with the movement of potentially damaging immune cells from your bloodstream to your brain and spinal cord.
  • Teriflunomide (Aubagio). This oral medication reduces attacks and lesions in people with MS.
  • Medications such as amantadine may help reduce fatigue due to multiple sclerosis.
  • Dalfampridine (Ampyra). This oral medication may improve walking speed in some people. The major side effect is seizures.
  • Muscle relaxants. If you have multiple sclerosis, you may experience painful or uncontrollable muscle stiffness or spasms, particularly in your legs. Muscle relaxants such as baclofen (Lioresal) and tizanidine (Zanaflex) may improve muscle spasticity
  • A physical or occupational therapist can teach you stretching and strengthening exercises and show you how to use devices that can make it easier to perform daily tasks.
  • For example, stem cell transplantation is being studied. In a stem cell transplant, doctors inject healthy stem cells into your body to replace diseased stem cells.
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    Though MS obviously has no cure there are plenty of procedures and medications that can be used to lessen the effects of the disease. Treating specific attacks reduces the damage to the myelin sheath. Two methods for controlling the attacks are plasma exchanges and corticosteroids. Another way to control the effects of MS is by slowing the progression of the disease. There are many different drugs that slow the rate of relapses some of which include Beta Interferons, Copaxone, Gilenya, and Tysabri. In addition to these medications, other strategies can be used to treat the symptoms, which include physical therapy and muscle relaxants. 
sami99

A Squirt of Stem Cell Gel Heals Brain Injuries | Popular Science - 0 views

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    Dr. Zhang's has created a liquid gel to insert into damaged parts of the brain from traumatic brain injuries. There has been little success on humans, but testing has been done on rats and there has been very positive results. On humans there has also been other techniques such as inserting donor cells into the damaged area but the cells end up dying off. Human success in the experiment is estimated to take up to 3 years. 
Nicholas Scholz

The effects of the brain in reproduction - 1 views

  • Properly functioning FSH (Follicle Stimulating Hormone) is needed to ensure fertility
  • Recently, the group of researchers at the University of Muenster (Germany) has analysed genetic variants in both the FSH gene and in the FSH receptor, which affect fertility in both males and females.
  • The group found that a distinct single nucleotide change in the DNA structure of FSHB gene (the FSH molecule has 2 subunits -- FSHB is the B subunit) caused significant effects in the functioning of the hormone in both men and women
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  • They found that males with the FSHB variation had significant drops in FSH levels and in testicular volume
  • However, the number of women with the combined variation so far studied was not high enough to draw significant conclusions.
  • We estimate that around 45% of infertile men would respond to FSH therapy
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    Reproduction is obviously a vital aspect of the human development. With a non-functioning fertility system future generations would be at a loss. Many problems could arise with infertility and ground-breaking research is finally being conducted. One of the important aspects of human reproduction is the use of hormones specifically FSH (Follicle Stimulating Hormone). This hormone is produced at the base of the brain stem and non-existing levels of FSH were recently associated with infertility. In order to regenerate these hormones a change has to be made in the FSHB subunit of the nucleotide. Infertility usually occurs after certain changes are made in the hormone levels and by redirecting the levels of hormones we may be able to alter the problems that arise during reproduction. It should also be noted that increases and decreases in the levels of FSH may have different effects depending on the gender of the patient. Current research estimates that the response of males to this therapy could positively effect nearly 45% of infertile men. Estimates could not be made for females as a result of insufficient research. 
aburbridge017

Stress can make the brain more susceptible to mental illness - Medical News Today - 0 views

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    The brain has a balance between "gray matter" and "white matter." People suffering from chronic stress tend to have more white matter, which is white tissue with a  myelin coating. Studies have shown that the stem cells in people with chronic stress mature into oligodendrocytes, which produce myelin. As a result, their learning and memory skills are affected because more oligodendrocytes are being produced instead of neurons. It is also believed that stress causes the hippocampus to become strongly connected to the amygdala, weakening the connection to the prefrontal cortex. This means that people with stress disorders have faster fear responses and have bigger responses to stressful situations than they normally would. 
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