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Facebook Exchange retargeting ads that appear within News Feed deliver an average increase in ROI of 197 percent compared to FBX ads on the right hand side of Facebook.com, according to an early study by Nanigans.

Sponsored Stories and Page Post Ads in the feed can have 10 to 20 times higher clickthrough rates than sidebar ads.

an average 17.1 times higher CTRs and 51 percent lower CPCs for FBX in News Feed versus in sidebar. As mentioned, ROI was 197 percent higher as a result.

Facebook recently announced that it will be extending Facebook Exchange (FBX) Retargeting into the News Feed, bringing the placement of these targeted ads beyond the network’s right-hand panel

Known as one of the strongest forms of targeting available in digital media, FBX helps marketers reach users on Facebook who have demonstrated interest through browsing behavior. By targeting users in a timely and contextually relevant manner, FBX can effectively drive sales, improve customer engagement, and promote brand awareness.

Ads in the News Feed have historically resulted in some of the strongest metrics compared with other locations.

BuzzSpice found that 72 percent of the pages it studied exhibited what it called “manic-depression behavior,” not posting content in a consistent manner, but adding posts in flurries, then going silent for more than two weeks, in some cases.

Pages that do not stay in constant touch with their fans get decreasing score on the Facebook EdgeRank algorithm, lose visibility, and eventually disappear from their fans’ News Feeds.

Twitter has confirmed our scoop with the announcement of Tailored Audiences - its name for retargeted ads. Available globally to all advertisers via a slew of adtech startup partners, advertisers will be able to target recent visitors to their websites with retargeted Promoted Tweets and Promoted Accounts.

Twitter’s users are on mobile. Seventy percent of its ad revenue already comes from the small screens, and it likely follows that a majority of engagement is on mobile, too.

retargeting happens like this. You visit a website, say a travel booking site, and look at a page for buying a flight to Hawaii. You chicken out at the last minute, don’t buy, and navigate away, but the site has dropped a cookie for that Hawaii flight page on your browser. Then, when you visit other sites or social networks that run retargeted ads, they detect that cookie, and the travel site can show you an ad saying “It’s cold in SF. Wouldn’t a vacation to Hawaii be nice?” to try to get you to pull the trigger and buy the flight it knows you were already interested in. But without cookies on mobile, you can’t retarget there… …unless you can tie the identity of a mobile user to what they do on the computer. And Twitter can. It’s one of the few hugely popular services that individuals access from multiple types of devices.