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jmlloren

Tiny octopus-like microorganisms named after science fiction monsters: Cthulhu - 2 views

shared by jmlloren on 05 Apr 13 - No Cached
LeopoldS liked it
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    Follow the link to PLoS and watch the video.
fichbio

Bacteria's Social Media - 2 views

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    Perhaps when you think of bacterial communities you think of a flask full of rapidly dividing E. coli. But in non-lab conditions, bacteria grow in complex, heterogeneous communities composed of diverse microscopic organisms. In these communities, bacteria need a means to communicate with their kin, and they do this through a language known as quorum sensing (QS), where bugs secrete and detect factors that tell them whether they're surrounded by kin (and if so, how many there are).
Luís F. Simões

Seminar: You and Your Research, Dr. Richard W. Hamming (March 7, 1986) - 10 views

  • This talk centered on Hamming's observations and research on the question "Why do so few scientists make significant contributions and so many are forgotten in the long run?" From his more than forty years of experience, thirty of which were at Bell Laboratories, he has made a number of direct observations, asked very pointed questions of scientists about what, how, and why they did things, studied the lives of great scientists and great contributions, and has done introspection and studied theories of creativity. The talk is about what he has learned in terms of the properties of the individual scientists, their abilities, traits, working habits, attitudes, and philosophy.
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    Here's the link related to one of the lunch time discussions. I recommend it to every single one of you. I promise it will be worth your time. If you're lazy, you have a summary here (good stuff also in the references, have a look at them):      Erren TC, Cullen P, Erren M, Bourne PE (2007) Ten Simple Rules for Doing Your Best Research, According to Hamming. PLoS Comput Biol 3(10): e213.
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    I'm also pretty sure that the ones who are remembered are not the ones who tried to be... so why all these rules !? I think it's bullshit...
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    The seminar is not a manual on how to achieve fame, but rather an analysis on how others were able to perform very significant work. The two things are in some cases related, but the seminar's focus is on the second.
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    Then read a good book on the life of Copernic, it's the anti-manual of Hamming... he breaks all the rules !
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    honestly I think that some of these rules actually make sense indeed ... but I am always curious to get a good book recommendation (which book of Copernic would you recommend?) btw Pacome: we are in Paris ... in case you have some time ...
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    I warmly recommend this book, a bit old but fascinating: The sleepwalkers from Arthur Koestler. It shows that progress in science is not straight and do not obey any rule... It is not as rational as most of people seem to believe today. http://www.amazon.com/Sleepwalkers-History-Changing-Universe-Compass/dp/0140192468/ref=sr_1_1?ie=UTF8&qid=1294835558&sr=8-1 Otherwise yes I have some time ! my phone number: 0699428926 We live around Denfert-Rochereau and Montparnasse. We could go for a beer this evening ?
Ma Ru

PLOS Computational Biology: Ten Simple Rules for Organizing an Unconference - 1 views

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    For future reference... At the same time, a crowdsourced article: "We began the crowdsourcing by collecting a list of possible rules for the article via a git-controlled repository" SVN would be so 2000-ish...
LeopoldS

PLOS ONE: Galactic Cosmic Radiation Leads to Cognitive Impairment and Increas... - 1 views

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    Galactic Cosmic Radiation consisting of high-energy, high-charged (HZE) particles poses a significant threat to future astronauts in deep space. Aside from cancer, concerns have been raised about late degenerative risks, including effects on the brain. In this study we examined the effects of 56Fe particle irradiation in an APP/PS1 mouse model of Alzheimer's disease (AD). We demonstrated 6 months after exposure to 10 and 100 cGy 56Fe radiation at 1 GeV/µ, that APP/PS1 mice show decreased cognitive abilities measured by contextual fear conditioning and novel object recognition tests. Furthermore, in male mice we saw acceleration of Aβ plaque pathology using Congo red and 6E10 staining, which was further confirmed by ELISA measures of Aβ isoforms. Increases were not due to higher levels of amyloid precursor protein (APP) or increased cleavage as measured by levels of the β C-terminal fragment of APP. Additionally, we saw no change in microglial activation levels judging by CD68 and Iba-1 immunoreactivities in and around Aβ plaques or insulin degrading enzyme, which has been shown to degrade Aβ. However, immunohistochemical analysis of ICAM-1 showed evidence of endothelial activation after 100 cGy irradiation in male mice, suggesting possible alterations in Aβ trafficking through the blood brain barrier as a possible cause of plaque increase. Overall, our results show for the first time that HZE particle radiation can increase Aβ plaque pathology in an APP/PS1 mouse model of AD.
Ma Ru

Ten Simple Rules for Starting a Company (PLOSCB) - 2 views

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    For those of you thinking of spin-offs.
Thijs Versloot

Counting whales from space #plos - 1 views

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    The WorldView2 satellite has a maximum 50 cm resolution and a water penetrating coastal band in the far-blue part of the spectrum that allows it to see deeper into the water column. Using an image covering 113 km2, we identified 55 probable whales and 23 other features that are possibly whales, with a further 13 objects that are only detected by the coastal band.
Alexander Wittig

Picture This: NVIDIA GPUs Sort Through Tens of Millions of Flickr Photos - 2 views

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    Strange and exotic cityscapes. Desolate wilderness areas. Dogs that look like wookies. Flickr, one of the world's largest photo sharing services, sees it all. And, now, Flickr's image recognition technology can categorize more than 11 billion photos like these. And it does it automatically. It's called "Magic View." Magical deep learning! Buzzword attack!
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    and here comes my standard question: how can we use this for space? fast detection of natural disasters onboard?
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    Even on ground. You could for example teach it what nuclear reactors or missiles or other weapons you don't want look like on satellite pictures and automatically scan the world for them (basically replacing intelligence analysts).
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    In fact, I think this could make a nice ACT project: counting seals from satellite imagery is an actual (and quite recent) thing: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092613 In this publication they did it manually from a GeoEye 1 b/w image, which sounds quite tedious. Maybe one can train one of those image recognition algorithms to do it automatically. Or maybe it's a bit easier to count larger things, like elephants (also a thing).
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    In HiPEAC (High Performance, embedded architecture and computation) conference I attended in the beginning of this year there was a big trend of CUDA GPU vs FPGA for hardware accelerated image processing. Most of it orbitting around discussing who was faster and cheaper with people from NVIDIA in one side and people from Xilinx and Intel in the other. I remember of talking with an IBM scientist working on hardware accelerated data processing working together with the Radio telescope institute in Netherlands about the solution where they working on (GPU CUDA). I gathered that NVIDIA GPU suits best in applications that somehow do not rely in hardware, having the advantage of being programmed in a 'easy' way accessible to a scientist. FPGA's are highly reliable components with the advantage of being available in radhard versions, but requiring specific knowledge of physical circuit design and tailored 'harsh' programming languages. I don't know what is the level of rad hardness in NVIDIA's GPUs... Therefore FPGAs are indeed the standard choice for image processing in space missions (a talk with the microelectronics department guys could expand on this), whereas GPUs are currently used in some ground based (radio astronomy or other types of telescopes). I think that on for a specific purpose as the one you mentioned, this FPGA vs GPU should be assessed first before going further.
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    You're forgetting power usage. GPUs need 1000 hamster wheels worth of power while FPGAs can run on a potato. Since space applications are highly power limited, putting any kind of GPU monster in orbit or on a rover is failed idea from the start. Also in FPGAs if a gate burns out from radiation you can just reprogram around it. Looking for seals offline in high res images is indeed definitely a GPU task.... for now.
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    The discussion of how to make FPGA hardware acceleration solutions easier to use for the 'layman' is starting btw http://reconfigurablecomputing4themasses.net/.
LeopoldS

PLoS Biology: Extreme Endurance Migration: What Is the Limit to Non-Stop Flight? - 1 views

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    the Alaskan bar-tailed godwit (Limosa lapponica baueri) (Figure 1), makes its eight-day, 11,000-km autumn migration from Alaska to New Zealand in one step, with no stopovers to rest or refuel. This roughly doubles the previous maximum direct flight distance in birds, challenging experts to square this remarkable marathon migration with our understanding of aerodynamic theory and endurance physiology.
LeopoldS

PLoS ONE: HAMLET Interacts with Lipid Membranes and Perturbs Their Structure and Integrity - 1 views

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    does not taste good but ....
LeopoldS

PLoS ONE: Dominance, Politics, and Physiology: Voters' Testosterone Changes on the Nigh... - 1 views

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    what does this tell about male behaviour ?? :-)
ESA ACT

PLoS ONE: Order in Spontaneous Behavior - 0 views

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    Free will in (stupid) fruit flies - that will make swarm behaviour even more difficult...
ESA ACT

PLoS Computational Biology - Machine Learning and Its Applications to Biology - 0 views

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    A Tutorial on machine learning. Esp. the unsupervised learning could be interesting.
ESA ACT

PLoS ONE: Order in Spontaneous Behavior - 0 views

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    Behavioral variations in fruit fly are not due to randomness but rather to decisions taken by the animal. Seems like free will.... also: http://brembs.net/spontaneous/
ESA ACT

PLoS ONE: Three-Dimensional Imaging of Drosophila melanogaster - 0 views

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    A new 3D microscope with amazing capabilities.
ESA ACT

PLoS ONE: The Fastest Flights in Nature: High-Speed Spore Discharge Mechanisms among Fungi - 0 views

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    Tobias have a look at this! 180 000 g acceleration!! LS
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