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Amanda Jara

Soap and Saponification - Chemistry - 4 views

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    We can relate this post on hydrolysis and what we just did this past chapter with solutions.
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    maybe we can also look at how different soaps utilize this technology
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    The chemistry behind soaps could be a really interesting topic. I know in AP Chemistry we were talking about how some soaps just remove the oils on your skin, but it is also really important for soaps to moisturize your skin as well as clean it so that your skin doesn't get really dry.
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    Sorry I just realized that that last comment wasn't totally related to the article but it is another aspect of soaps that we could look into. It could also be interesting to compare the ingredients of different soaps and see if the differences really affect their performance.
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    It's not related to this article but it is related to what we're learning in class/cosmetics - I smell a possible blog post.
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    Going off of what Katie said about soaps removing the oils on you skin, I know some people who have really sensitive skin and actually break out into rashes after using certain soaps. Maybe we can look why that happens, (is it the removal of oils, or the addition of chemicals that are supposed to help moisturize the skin). From there we can probably find the ingredient that leads to such effects.
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    That's a good idea - the "or." Perhaps it is actually both? And these ingredients that supposedly help moisturize your skin, how are they passing testing if they dry it out? Things to look into.
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    It looks like a this topic could really tie in with the last topic in advanced chem in terms of polar and non-polar molecules. Yay connections :)
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    Maybe we can go even further and see if it is the different combinations of ingredients that causes reactions. Perhaps it may be the case that one ingredient may be harmless if it is alone, but when combined with something else, it can change its properties.
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    I'm in the process of writing a blog post on soaps, and iin my research, I basically found that soaps are made from fats and salts, which make the non polar and polar, and so that lets them bind to non polar things like grease and polar things like water, and they lets them wash stuff away. Thats a way we can relate this to the stuff we're learning in class :)
Andrew Kang

Topical simvastatin shown to accelerate wound healing in diabetes - 3 views

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    maybe we should look at the chemistry behind simvastatin - how it can penetrate the skin? after that it's a lot of biology 
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    Really interesting article although this seems to be straying a little from cosmetics. It also might be hard to relate this back to what we are discussing in class. Looking at cosmetics that also help heal people's bodies could be a possible blog post.
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    Yeah that's what I was worried about. And good idea!
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    I like the idea of just looking at how it penetrates the skin, and I think we can relate it back to cosmetics through that because a lot of cosmetic products need to find effective ways to get their ingredients to penetrate the skin, because otherwise, they wouldn't really work. just an idea
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    Kind of going off of what Katie said about cosmetics healing the body, you can always find the foundation commercials advertising regenerating ingredients that "take years off your face." it can be a different angle to discuss instead of usual topic of how facial cosmetics cause premature aging.
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    People often forget that cosmetics also encompasses things that benefit your health as well. I made one blog post already about how anti-aging creams work but I never looked at foundation and other products.
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    That could be a really cool blog post Andrew- makeup that is actually beneficial to your skin. I know there are some concealers that not only cover acne but actually contain ingredients that help heal it! I'm sure there are lots of other products like that.
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    A lot of commercials say that their product will help clear skin, but how many actually do? And what do they use to do it?
Katie Rigdon

Cosmetic Chemistry Lab Uses New Pentapharm Peptide In Potent Anti-Aging Eye Serum - 0 views

    • Katie Rigdon
       
      Anticoagulants, antifibrinolytics and haemostatics are three more topics to pursue under teh larger topic of anti-aging cosmetics
  • anticoagulants, antifibrinolytics and haemostatics.
  • Syn-Coll,
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  • Syn-Coll stimulates the collagen synthesis in human fibroblasts. Skin aging and chronic UV exposure particularly, leads to degenerative changes in skin. The degenerative changes in skin are characterized by distinct alterations in the composition of the dermal extra cellular matrix.
  • Tissue growth factor is known as the key element in the synthesis of collagen and binds to a particular sequence in the TSP molecule. This sequence is known as ARG-PHE-LYS.
  • As a molecule able to activate TGF, Syn-Coll is considered to be an ideal aqueous based peptide. It contains a unique sequence designed to mimic the human body's own mechanism to product collagen via TGF. Accordingly, Syn-Coll actively compensates for any collagen deficit, thus making the skin look younger and rejuvenated.
  • The results of the Syn-Coll clinical studies are astounding. After 84 days of twice-daily application, a panel of 60 volunteers experienced 2.5% Syn-Coll parameters average relief (Rz) and maximum relief (Rt) significantly decreased by -12%: -22 μm and -36 μm respectively (p= 0.05) characterizing smoothing and anti wrinkle effects.
    • Katie Rigdon
       
      Looks like this ingredient actually works!
Jenny Mu

Skin Deep - Gold Face Cream - A Costly Leap of Faith - NYTimes.com - 1 views

  • People who sell creams with visible gold flecks talk about the ability of those flecks to warm the skin and make it conducive to other ingredients. People who sell gold in nano form — that is, in microscopic particles suspended in a liquid mixture known as a colloid — look down on this crowd, saying that gold can confer benefits only when it is broken down small enough to penetrate the skin.
  • But is it true that gold has therapeutic qualities? That depends if you ask someone who is selling it suspended in cream or someone who went to medical school. Dermatologists speak with one voice, saying that gold cannot help you, but it absolutely can hurt you, causing inflammatory reactions like contact dermatitis (which may be what happened to me). In high doses, gold can be toxic, but these products probably don’t contain enough of it to make that happen, doctors say.
  • At best, they do nothing, and at worst, they can give you irritation of the skin,”
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  • “intensive medical searches on this very ingredient” and found that “there are absolutely no scientific studies that show that gold has any effect in firming or revitalizing the skin, nor that it reduces wrinkles or gives skin a plumped, golden glow.”
  • “Colloidal gold does help to maintain your skin’s elasticity and firmness,” she said. “Gold itself is known to have very soothing benefits to it.”
  • a line of products that contain colloidal platinum — including a cream that costs $1,000 an ounce
  • outlined a number of benefits: gold, she said, is hypoallergenic, stimulates blood circulation, reduces sunspots and acts as an antioxidant.
  • “The gold actually acts like a small charger, because it’s metal and we have electricity in our bodies,” she said. “Whenever gold comes into contact with our bodies, it gives a boost of activity, which is good for restoring the lost elasticity properties of the tissue.”
  • Cosmetics makers also habitually cite the use of gold in medicine, where it is given to patients with rheumatoid arthritis and has been used — only experimentally — as a possible cancer treatment. Debabrata Mukhopadhyay, a professor and cancer researcher at the Mayo Clinic, said that while gold nanoparticles show promise, they are “highly toxic when injected in high doses in mice.” And the size of the nanoparticles matters a lot, he said, adding that it was unclear if the particles in the gold face creams were the right size to penetrate the skin.
  • “As a scientist, I am very skeptical unless I see research,”
  • Ms. Genovese pointed out that people keep buying her company’s gold line because they perceive that it works.
    • Jenny Mu
       
      Gold nanoparticles do have a lot of applications in research, but in skincare??
    • Jenny Mu
       
      Clearly, there are no benefits in gold face creams.
    • Jenny Mu
       
      This just goes to show that these cosmetic companies are just using whatever material is more expensive in their face creams so they can jack up the price. First gold, then platinum...
    • Jenny Mu
       
      This seems like a load of nonsense, but maybe this warrants further research.....
    • Jenny Mu
       
      placebo effect?
Jenny Mu

Nanomaterials and Hormone Disrupters in Sunscreens | EWG's Skin Deep® | 2012 ... - 1 views

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    This site gives a really good overview of the top ingredients in sunscreens, and their pros and cons. 
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    Katie - I think this would help with your blog post
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    So it seems that the biggest concerns with sunscreens and their components is that some of the components, like mineral formulations like zinc oxide and titanium dioxide, or oxybenzone, are small enough to penetrate the skin and be toxic!
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    Like you mentioned before, toxicity is something interesting we could look into. Toxicity with regard to both us as humans, and our environment, like the aquatic life that would come into contact with some of the chemicals in these sunscreens. Katie, maybe you should add this to your blog post :)
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    I definitely will add this! Looks like some really helpful information that people should know about.
Jenny Mu

INGREDIENTS: Figuring out what's "hypo-allergenic" and "non-comedogenic" - 0 views

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    This is an easy to read, interesting blog post about the usage of worlds like "hypo-allergenic" and "non-comedogenic" on cosmetics, and what it actually means chemically for products to be labelled with those words. This kind of addresses what we were talking about on the simvastatin article, about cosmetics that can help clear skin Things that are non-comedogenic do not necessarily clear skin, but they do not cause acne. We could start there, looking at chemical compounds in cosmetics that can cause acne and that don't cause acne and then look into how to treat it.  
Amanda Jara

Skin Deep - Gold Face Cream - A Costly Leap of Faith - NYTimes.com - 2 views

    • Amanda Jara
       
      we can look up other common ingredients that cause allergic reactions...ie arbutin
    • Katie Rigdon
       
      I think allergies could be a really interesting topic to add to our blog because, like Jenny said, we are kind of all over the place and I think we need some topics so skin allergies (to things in cosmetics) could be one of them!
    • Jenny Mu
       
      But we also have to keep the topic focused on chemistry, and allergies could really easily go into biology or something like that. but there is a chemistry side to allergies too, so maybe that could work
    • Andrew Kang
       
      The article kept stressing the benefits of colloidal gold as opposed to gold in flakes or just applied to the skin. Perhaps we could look at nanochemistry in cosmetics - it was nanoparticles that gave the colloidal cream its advantage and with anything you apply to your skin perhaps there is consideration given to the substance on the molecular scale for its efficacy.
    • Jenny Mu
       
      But we should also consider the element itself. Whether in nanoparticles or in flakes, what scientific evidence is there that gold is good for the skin? Or is it just one big, expensive scam...
Jenny Mu

snopes.com: Sodium Lauryl Sulfate and Shampoo - 4 views

shared by Jenny Mu on 15 Nov 12 - Cached
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    this is the article I talked about before about the email chain with the myth of sodium lauryl sulfate and cancer
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    Interesting on how certain aspects of a product can be made out to be much worse than they really are. While some ingredients may be fatal, there are others that seem to have exaggerated effects and aren't too bad.
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    yeah It's funny how some rumors start. this article mentions that people thought SLS would degrade into nitrosamines, which are carcinogenic, but that doesn't make any sense at all since there isn't even a nitrogen in SLS, but there are in nitrosamines... welp that reminds you that there are some really uneducated people in society
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    wow shampoo sham must be one among many other things blown up to be worse than they really are. everyone is so quick to be wary of a chemical just because it has a long name or strong properties outside of its use in cosmetics. i wonder what other kinds of products people are sensationalizing as dangerous like this.
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    So it looks like it's actually really important to check our sources and make sure that we are looking at information that is actually based on scientific experiment and not just hearsay. We should probably also cross check information to make sure that it appears in multiple places on the internet as opposed to using just one, non-reliable source.
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    I agree that we should double check where we are getting our information from. But it may also be a cool idea to compare what people think they know about a product and the actual data. We can see how far off people are from the truth and if the myths and rumors are even remotely close to what is really going on, chemically.
Amanda Jara

The Health (and Beauty) Dangers of Common Soap & A Top-Recommended Alternative - 1 views

  • These are some of the most common health symptoms that studies have linked to ingredients found in common commercial soaps and commercial personal care products:
  • Today, 75% of liquid soaps and over 30% of bar soaps in the US are antibacterial, all containing the synthetic chemical triclosan.
  • Has been shown to kill your skin cells
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  • Dries your skin
  • Can aggravate skin disorders such as eczema and psoriasis Does nothing to prevent most illnesses, since colds, flues and more are typically viral (and antibacterial only kills bacteria, not viruses) Dioxin, a highly carcinogenic may be formed during the manufacturing process of triclosan, making it a likely contaminant.
    • Jenny Mu
       
      It seems as though there was one of the email chains going around in the nineties that said that SLS was a carcinogen, Snopes did an article on it,where they found that the myth was false Even though SLS is not a carcinogen we can see if it has other health effects
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    I don't know if we could actually take anything from this site, but it's a really good place start looking into. It seems that triclosan and Sodium Lauryl Sulfate are big issues that can be further researched. They are very likely to be found in other body cleansing cosmetics.
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    I definitely agree that Sodium Lauryl Sulfate is a pretty big issue, you always see products boasting that they are "Sulfate free!" and what not. I believe I actually tweeted about SLES a while back, but never expanded upon it. But I think we should do more research into what makes that compound so dangerous and why its bad to be in personal products
Jenny Mu

Beauty Antioxidants: Facial Attraction | Nutritional Outlook - 0 views

  • And while these are all products that are topically applied—a concept consumers are familiar and comfortable with—more consumers are coming around to the idea that the same ingredients that are found in lotions and potions might also be able to influence outward appearance when incorporated in the diet.
    • Jenny Mu
       
      Which way is better? topical treatments or oral ingestion
  • “There is human clinical evidence that these yellow carotenoids act like internal sunscreen to protect and improve skin health,” he says, referring to a 2007 study that tested the oral and topical effects of lutein and zeaxanthin over 12 weeks. (P Palombo et al., “Beneficial long-term effects of combined oral/topical antioxidant treatment with the carotenoids lutein and zeaxanthin on human skin: a double-blind, placebo-controlled study,” Skin Pharmacology and Physiology, vol. 20, no. 4 (2007):199-210.) “Statistically significant, favorable effects were seen on three skin function outcomes, including hydration, photoprotection, and lipid damage,” says Bhattacharya. “Higher oral doses of zeaxanthin were shown to provide effective protection against sunburn, which could help reduce the risks of skin cancer, premature aging, and wrinkling.”
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    • Jenny Mu
       
      What inside them is acting like an internal sunscreen? Chemically, how does it work?
  • Pycnogenol is one of the few antioxidants shown to effectively neutralize all oxygen radical species. It says this is especially important to the skin, as even low-to-moderate UV exposure generates oxygen radicals in the dermis.
    • Jenny Mu
       
      Neutralization of oxygen radical species. Once again, we should look into the chemical process of how this happens. The transfer of electrons etc.
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