water soluble formulation - 0 views
-
crystalpharmate on 26 Dec 24Bioavailability Enhancement for Insoluble Compounds & PROTAC & Oral Peptides Recent statistics indicate that approximately 40% of currently marketed drugs and nearly 90% of candidates in R&D pipeline belong to Biopharmaceutics Classification System (BCS) II or IV poorly water-soluble drugs. Consequently, enhancing drug solubility and improving bioavailability are pressing challenges in the realm of new drug development. Widely employed methods for solubility enhancement include: