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sdahlseng10

Improved lentiviral vectors for Wiskott-Aldrich syndrome gene therapy mimic... - 0 views

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    Supplemental Article to Lesch et al. (2011): This article talks about one of the disorders that is treatable by gene therapy: a relatively rare x-linked chromosomal abnormality that causes immunodeficiency as a result of hematopoietic cell damage causing inefficient T-cell receptor binding. Lentiviruses appear to be good vectors for the gene therapy treatment of this disorder as a highly regulated therapy is required for a beneficial outcome.
Casey Finnerty

'Binding, bending and bonding': polypurine tract-primed initiation of plus-strand DNA s... - 0 views

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    This review describes nicely HIV replication and the role of the PPTs.
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