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Katelyn Madigan

'Quadruple helix' DNA discovered in human cells - 0 views

  • our-stranded 'quadruple helix' DNA structures -- known as G-quadruplexes
  • rich in the building block guanine
  • over 10 years investigation by scientists to show these complex structures in vivo -- in living human cells
  • ...2 more annotations...
  • quadruplexes are more likely to occur in genes of cells that are rapidly dividing, such as cancer cells.
  • quadruplex DNA is found fairly consistently throughout the genome of human cells and their division cycles
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    A better understanding of DNA structure, as well as other factors at the molecular level, have tremendous clinical implications. A personalized inhibitory mechanism for proliferating cancer cells looks like a promising approach for cancer treatments.
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