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Casey Finnerty

Eggs, Too, May Provoke Bacteria to Raise Heart Risk - NYTimes.com - 0 views

  • The lecithin study, published Wednesday in The New England Journal of Medicine, is part of a growing appreciation of the role the body’s bacteria play in health and disease. With heart disease, investigators have long focused on the role of diet and heart disease, but expanding the scrutiny to bacteria adds a new dimension.
  • “Heart disease perhaps involves microbes in our gut,”
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    First carnitine and meat, now lecithin and eggs! Darn it! All things in moderation, I guess.
anonymous

Gut bugs are implicated in heart attacks and stroke - 0 views

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    Gut bacteria turns lecithin, which is within egg yolks, liver, beef, pork and wheat into TMAO causing heart disease. Stroke and heart attack can be caused by the potent TMAO, which hardens the artery by cholesterol build up on the artery walls. A nutrient within red meat and dairy, carnitine, can be transformed to TMAO by gut bugs. However, this is usually only in frequent meat eater. People that infrequently each meat reducing the amount of gut bacteria to transform the carnitine into TMAO.
Jenna Veldhuizen

Scientists build a living patch for damaged hearts - 0 views

  • the patch conducts electricity at about the same speed as natural heart cells and it "squeezes" appropriately
  • closest man-made approximation of native human heart tissue to date
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    very cool!
Katelyn Madigan

Viral reactivation a likely link between stress and heart disease - 1 views

    • Katelyn Madigan
       
      It is important not to exaggerate your findings, so I think it is good that they are honest with areas of the research that are still not definitive.
  • enhanced levels of proinflammatory proteins in the blood of patients with acute coronary events and detectable levels of the EBV-related protein
  • having more of one of these proteins in the blood was linked to the presence of antibodies that signal a latent Epstein-Barr virus
  • ...4 more annotations...
  • looked for antibodies against a protein that can be produced even when only partial or incomplete reactivation of Epstein-Barr EBV occurs
  • EBV, a human herpes virus that causes infectious mononucleosis and several different types of tumors
  • Stress is a known predictor of reactivation of EBV, meaning virus reactivation could be a mechanism by which stress leads to chronic inflammation and eventually cardiovascular diseases.
  • viral proteins can induce inflammation, affecting the lining of blood vessels, so that inflammation is in the right place to function as a significant risk factor for heart disease
Casey Finnerty

Molecule in meat may increase heart disease risk | Genes & Cells | Science News - 3 views

  • Hazen’s group also found that blood levels of TMAO and L-carnitine could predict heart disease risk, which they learned by collecting blood samples from 2,595 patients and tracking their health for three years.
    • Casey Finnerty
       
      That is a fairly large sample size and long term study.
  • Molecules proposed as biomarkers for heart disease often look promising in initial studies but fizzle out clinically. “We’ve been down this road so many times before.”
    • Casey Finnerty
       
      Very true.
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    This is an interesting story on how the microbiota of our gut may play an indirect role in cardiovascular disease.
Casey Finnerty

Study Points to New Culprit in Heart Disease - NYTimes.com - 0 views

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    NYTimes report on Nathan's post about carnitine and it's conversion to TMAO by gut bacteria.
Casey Finnerty

A New Germ Theory - 99.02 - 0 views

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    The recent papers from the Cleveland Clinic on the role of microbiome in heart disease jogged my memory of Paul Ewald's work on this subject. In a way, he predicted the papers that appeared this week over 15 years ago. Put succinctly, "big, old, diseases are infectious." If they weren't, natural selection would have reduced their incidence. Fascinating theory, worth a read.
Charles Bach

Gut bacteria byproduct predicts heart attack and stroke - 0 views

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    Looking at the micro flora in the gut researchers are showing that this correlates to heart disease. Another story of the great importance of bacteria in our bodies.
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