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Contents contributed and discussions participated by Marie-Lise Pagé

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Clues to addiction | Harvard Gazette - 0 views

news.harvard.edu/...clues-to-addiction addiction science
shared by Marie-Lise Pagé on 05 Mar 12 - No Cached
  • neurons in the brain interact to reinforce behaviors ranging from learning to drug use
  • prediction error has long been considered the product of dopamine neurons firing in response to an unexpected “reward,
  • reward prediction error is actually the product of a complex interplay between two classes of neuron
    • Marie-Lise Pagé
      Marie-Lise Pagé on 05 Mar 12
       
      Dopamine is not the only hormone having a role in the addiction.
  • ...9 more annotations...
  • one that relies on dopamine
  • an inhibitory class of neurons that uses the neurotransmitter GABA.
  • GABA neurons
  • are inhibiting the dopamine neurons
    • Marie-Lise Pagé
      Marie-Lise Pagé on 05 Mar 12
       
      Both are working together to provoque the addiction.
  • GABA neurons help dopamine neurons calculate reward prediction error.
    • Marie-Lise Pagé
      Marie-Lise Pagé on 05 Mar 12
       
      ** Research more about the reward prediction error
  • it sheds new light on how behaviors can be reinforced,
  • many drugs, such as opioids and cannabinoids, target the GABA neurons,”
  • by inhibiting those GABA neurons, you can lose this feedback cycle, so you keep getting reinforcing signals from the dopamine neurons.
  • new theories or treatments for addiction.”
    • Marie-Lise Pagé
      Marie-Lise Pagé on 05 Mar 12
       
      Good to cure addiction and help many people but at the same time should we play with their body to get rid of their addiction?
  • Marie-Lise Pagé on 05 Mar 12
     
    The article talks about the reactions of neurons to addiction and a cure can be found.
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Addicts' Brains May Be Wired At Birth For Less Self-Control : Shots - Health Blog : NPR - 2 views

www.npr.org/...at-birth-for-less-self-control addiction brains
shared by Marie-Lise Pagé on 05 Mar 12 - No Cached
  • inherit a brain that has trouble
  • ocaine addicts have abnormalities in areas of the brain involved in self-control.
    • Marie-Lise Pagé
      Marie-Lise Pagé on 05 Mar 12
       
      It's the part in the brain that controls self-control that causes addiction.
  • predate
  • ...13 more annotations...
  • both siblings had brains unlike those of typical people
  • longer for a "stop" message to get through.
    • Marie-Lise Pagé
      Marie-Lise Pagé on 05 Mar 12
       
      Maybe that's why it takes time for people to get over their addiction or they easily give in to peer pressure.
  • different parts of the brain were less efficient in both,"
  • took longer than a typical person to respond to a signal telling them to stop performing a task.
  • less self-control.
  • siblings without drug problems also had impaired self-control offers strong evidence that these brain abnormalities are inherited,
  • "How do they manage with an abnormal brain without taking drugs?"
    • Marie-Lise Pagé
      Marie-Lise Pagé on 05 Mar 12
       
      That's the part i don't understand to the study... try research more on this.
  • Self-control and the ability to regulate your emotions
  • allows us to succeed,
  • the part of the brain that decides whether to take a drug is also the part that helps us decide whether to speed through a yellow light or drop out of school,
    • Marie-Lise Pagé
      Marie-Lise Pagé on 05 Mar 12
       
      Maybe that's the answer to the question in green, instead of being drugs it's minor decisions like that.
  • mpulse control is also central to behaviors like compulsive gambling and compulsive eating, she says.
    • Marie-Lise Pagé
      Marie-Lise Pagé on 05 Mar 12
       
      Other examples of addiction behaviours.
  • help researchers figure out how to help susceptible people strengthen their self-control,
  • Predetermination is not predestination,
    • Marie-Lise Pagé
      Marie-Lise Pagé on 05 Mar 12
       
      ** Research the meaning of this quote.
  • Marie-Lise Pagé on 05 Mar 12
     
    This site explains what the brain looks like when someone is addicted.
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