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Contents contributed and discussions participated by Marie-Lise Pagé

Marie-Lise Pagé

Clues to addiction | Harvard Gazette - 0 views

  • neurons in the brain interact to reinforce behaviors ranging from learning to drug use
  • prediction error has long been considered the product of dopamine neurons firing in response to an unexpected “reward,
  • reward prediction error is actually the product of a complex interplay between two classes of neuron
    • Marie-Lise Pagé
       
      Dopamine is not the only hormone having a role in the addiction.
  • ...9 more annotations...
  • one that relies on dopamine
  • an inhibitory class of neurons that uses the neurotransmitter GABA.
  • GABA neurons
  • are inhibiting the dopamine neurons
    • Marie-Lise Pagé
       
      Both are working together to provoque the addiction.
  • GABA neurons help dopamine neurons calculate reward prediction error.
    • Marie-Lise Pagé
       
      ** Research more about the reward prediction error
  • it sheds new light on how behaviors can be reinforced,
  • many drugs, such as opioids and cannabinoids, target the GABA neurons,”
  • by inhibiting those GABA neurons, you can lose this feedback cycle, so you keep getting reinforcing signals from the dopamine neurons.
  • new theories or treatments for addiction.”
    • Marie-Lise Pagé
       
      Good to cure addiction and help many people but at the same time should we play with their body to get rid of their addiction?
  •  
    The article talks about the reactions of neurons to addiction and a cure can be found.
Marie-Lise Pagé

Addicts' Brains May Be Wired At Birth For Less Self-Control : Shots - Health Blog : NPR - 2 views

  • inherit a brain that has trouble
  • ocaine addicts have abnormalities in areas of the brain involved in self-control.
    • Marie-Lise Pagé
       
      It's the part in the brain that controls self-control that causes addiction.
  • predate
  • ...13 more annotations...
  • both siblings had brains unlike those of typical people
  • longer for a "stop" message to get through.
    • Marie-Lise Pagé
       
      Maybe that's why it takes time for people to get over their addiction or they easily give in to peer pressure.
  • different parts of the brain were less efficient in both,"
  • took longer than a typical person to respond to a signal telling them to stop performing a task.
  • less self-control.
  • siblings without drug problems also had impaired self-control offers strong evidence that these brain abnormalities are inherited,
  • "How do they manage with an abnormal brain without taking drugs?"
    • Marie-Lise Pagé
       
      That's the part i don't understand to the study... try research more on this.
  • Self-control and the ability to regulate your emotions
  • allows us to succeed,
  • the part of the brain that decides whether to take a drug is also the part that helps us decide whether to speed through a yellow light or drop out of school,
    • Marie-Lise Pagé
       
      Maybe that's the answer to the question in green, instead of being drugs it's minor decisions like that.
  • mpulse control is also central to behaviors like compulsive gambling and compulsive eating, she says.
    • Marie-Lise Pagé
       
      Other examples of addiction behaviours.
  • help researchers figure out how to help susceptible people strengthen their self-control,
  • Predetermination is not predestination,
    • Marie-Lise Pagé
       
      ** Research the meaning of this quote.
  •  
    This site explains what the brain looks like when someone is addicted.
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